Ovarian cancer: from risks to prevention. See genetic factors, hormones, age and reproductive history, symptoms, screening limits, lifestyle changes, and care options in our web story.

RISKS AND PREVENTION

WHAT CAUSES OVARIAN CANCER

OVARIAN CANCER OVERVIEW

Ovarian cancer is heterogeneous: epithelial, germ cell, and stromal types. Early awareness and prompt care improve outcomes.

HOW IT DEVELOPS: MUTATIONS AND DNA DAMAGE

Cellular mutations and DNA damage drive uncontrolled growth. When repair pathways fail, cancer risk rises.

ROLE OF HORMONES

Estrogen exposure and reproductive history influence risk. Fewer lifetime ovulations may be protective.

GENETIC RISK: BRCA AND LYNCH

BRCA1/2 and Lynch syndrome markedly raise risk. Genetic counseling and testing are advised with family history.

DOES IT RUN IN FAMILIES?

Yes. Families with breast/ovarian cancer may carry inherited mutations. Screening and prevention are personalized.

AGE, PREGNANCY, AND MENOPAUSE

Risk increases with age; most cases postmenopausal. Pregnancy and parity generally lower risk.

HRT, ENDOMETRIOSIS, AND PCOS

Prolonged HRT may raise risk. Endometriosis is associated. PCOS link appears modest; evidence is mixed.

BIRTH CONTROL AND LIFESTYLE

Oral contraceptives can reduce risk. Healthy weight, diet, avoiding smoking, and activity are protective.

PREVENTION AND GENETIC TESTING

Lifestyle changes, oral contraceptives, risk reducing surgery in high risk, and regular surveillance help.

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