Assoc. Prof. MD. Halil Can

Advanced Neurosurgical Care: Precision and Innovation in Brain and Spine Surgery at Istinye University Liv Hospital Topkapı

Halil Can provides advanced neurosurgical care at İstinye University Liv Hospital Topkapı, delivering specialized surgical treatment for complex disorders of the brain, spine, and nervous system. His clinical practice is founded on precision, safety, and evidence-based neurosurgical techniques aimed at optimizing patient outcomes.

Specializing in neurosurgery, Can works within a multidisciplinary medical framework to ensure accurate diagnosis, comprehensive surgical planning, and effective postoperative management. He utilizes modern surgical technologies and minimally invasive approaches when appropriate to support functional recovery and improve quality of life.

Committed to clinical excellence and continuous professional development, Halil Can aligns his practice with contemporary neurosurgical standards and international guidelines. His patient-centered approach emphasizes careful evaluation, clear communication, and individualized treatment strategies, ensuring high-quality neurosurgical care tailored to each patient’s condition and needs.

• 1- Clinical Study of Decompressive Craniectomy in Children. Goker B, Guclu DG,      Dolas I, Ozgen U, Altunrende ME, Akinci AT, Sencan F, Aydoseli A, Can H, Sencer A. Turk Neurosurg. 2020;30(2):225-230.
• 2- Kyphoplasty in the Early Oncologic Diagnosis and Treatment of Vertebral Fractures: A Clinical Study. Akyuva Y, Baysoy B, Savrunlu EC, Sezen GB, Boyali O, Can H, Civelek E, Kabatas S. Turk Neurosurg. 2020;30(4):588-594.
• 3-  Subacute Traumatic Ascending Myelopathy in a 28-Year-Old Man: A Rare Case. Aydoseli A, Özgen U, Akgül T, Orhan EK, Adıyaman AE, Can H, Karadağ C. World Neurosurg. 2019 Aug;128:143-148.
• 4- Anatomical Features of Neural Foramen at T12-L1 Level for Endoscopic Transforaminal Approach of Paramedian and Foraminal Disc Herniations: An Anatomical Study on Fresh Human Cadavers. Can H, Gomleksiz C, Diren F, Civelek E, Kircelli A, Aydoseli AN, Sencer A. Turk Neurosurg. 2020;30(1):78-82.
• 5- Morphometric Analysis of Lumbar Arteries and Relationship with Intervertebral Discs: A study of Surgical Anatomy on Human Fresh Cadavers. Can H, Diren F, Peker B, Gomleksiz C, Guclu DG, Kucuk C, Civelek E, Aydoseli A, Sencer A. Turk Neurosurg. 2020;30(4):577-582.
• 6- Comprehensive Anatomic and Morphometric Analyses of Triangular Working Zone for Transforaminal Endoscopic Approach in Lumbar Spine: A Fresh Cadaveric Study. Can H, Unal TC, Dolas I, Guclu G, Diren F, Dolen D, Gomleksiz C, Aydoseli A, Civelek E, Sencer A. World Neurosurg. 2020 Jun;138:e486-e491.
• 7- A new lumbar fixation device alternative to pedicle-based stabilization for lumbar spine: In vitro cadaver investigation. Gomleksiz C, Erbulut DU, Can H, Kodigudla MK, Kelkar AV, Kasapoglu E, Ozer AF, Goel VK. J Spinal Cord Med. 2020 Jan;43(1):98-105.
• 8- Anatomic Assessment of Variations in Kambin's Triangle: A Surgical and Cadaver Study. Ozer AF, Suzer T, Can H, Falsafi M, Aydin M, Sasani M, Oktenoglu T. World Neurosurg. 2017 Apr;100:498-503.
• 9-   Lumbosacral Conjoined Root Anomaly: Anatomical Considerations of Exiting Angles and Root   Thickness. Can H, Kircelli A, Kavadar G, Civelek E, Cansever T, Aydoseli A, Onal, MB, Yilmaz C. Turk Neurosurg. 2017;27(4):617-622.
• 10-  Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury. Can H, Aydoseli A, Gömleksiz C, Göker B, Altunrende ME, Dolgun M, Sencer A. Ulus Travma Acil Cerrahi Derg. 2017;23(6):452-458.
• 11-  Memantine and Q-VD-OPh Treatments in Experimental Spinal Cord Injury: Combined Inhibition of Necrosis and Apoptosis. Aydoseli A, Can H, Aras Y, Sabanci PA, Akcakaya MO, Unal OF. Turk Neurosurg. 2016;26(5):783-9.
• 12-  The clinical factors associated with benefit finding of complementary medicine use in patients with back pain: A cross-sectional study with cluster analysis. Kavadar G, Demircioğlu DT, Can H, Emre TY, Civelek E, Senyigit A. J Back Musculoskelet Rehabil. 2017;30(2):271-277.
• 13-  Is the presence of linear fracture a predictor of delayed posterior fossa epidural hematoma? Kırcelli A, Özel Ö, Can H, Sarı R, Cansever T, Elmacı İ. Ulus Travma Acil Cerrahi Derg. 2016 Jul;22(4):355-60.
• 14-  Effects of combined and individual use of N-methyl-D aspartate receptor antagonist magnesium sulphate and caspase-9 inhibitor z-LEDH-fmk in experimental spinal cord injury. Sencer A, Aydoseli A, Aras Y, Akçakaya MO, Gömleksiz C, Can H, Canbolat A. Ulus Travma Acil Cerrahi Derg. 2013 Jul;19(4):313-9.
• 15-  Spinal cavernous malformations: a report of 5 cases. Cansever T, Civelek E, Sencer A,  Karasu A, Kiriş T, Hepgül K, Can H, Canbolat A. Surg Neurol. 2008 Jun;69(6):602-7; discussion 607.
• 16-  KABATAŞ SERDAR,CİVELEK ERDİNÇ,KAPLAN NECATİ,Savrunlu Eyüp Can,Sezen Gülseli Berivan,Chasan Mourat, CAN HALİL, AKYUVA YENER,BOYALI OSMAN,DİREN FURKAN,KARAÖZ ERDAL (2021). Phase I study on the safety and preliminary efficacy of allogeneic mesenchymal stem cells in hypoxic-ischemic encephalopathy. World J Exp Med, 11(2), 17-29., Doi: 10.5493/wjem.v11.i2.17. (Yayın No: 9692827)
• 17-  GÜÇLÜ DOĞAN GÜÇLÜHAN,ÖZTÜRK ONUR, ÇIRAK MUSA, CAN HALİL, ÜNAL TUĞRUL CEM, DOLAŞ İLYAS,ÖZGEN UTKU,AYDOSELİ AYDIN,SENCER ALTAY (2022). A series of post-traumatic midline epidural hematoma and review of the literature. Ulus Travma Acil Cerrahi Derg, 28(6), 805-811., Doi: 10.14744/tjtes.2020.28182 (Yayın No: 9756957)
• 18-  DOLAŞ İLYAS,ÜNAL TUĞRUL CEM,GÜLSEVER CAFER İKBAL,Huseynov Heydar,BARBUROĞLU MEHMET,ÖZTÜRK ONUR, CAN HALİL, ADIYAMAN ALİ EKREM,Dağdeviren Hüseyin Emre,SABANCI PULAT AKIN,AYDOSELİ AYDIN,ARAS YAVUZ,SENCER ALTAY,SENCER NEBİYE SERRA (2023). Endovascular treatment of posterior circulation aneurysms: Results from a single-team experience of 81 cases including 13 flow diversion treatment. Neurocirugia (Engl Ed), 34(4), 168-176., Doi: 10.1016/j.neucie.2022.11.022 (Yayın No: 9756363)
• 19-  CAN HALİL, ÖZTÜRK ONUR,CİVELEK ERDİNÇ,DOĞU HÜSEYİN,BOYALI OSMAN,KÜÇÜK CEYHUN,AYDOSELİ AYDIN,SENCER ALTAY (2024). A Morphometric Study of Cadavers for the Anterior Approach to the Lower Lumbar Spine. Turkish Neurosurgery, 34(4), 640-646.Doi: 10.5137/1019- 5149.JTN.43447-23.2 (Yayın No: 9608434)
• 20-  KABATAŞ SERDAR,CİVELEK ERDİNÇ,Savrunlu Eyüp Can,KAPLAN NECATİ,BOYALI OSMAN,DİREN FURKAN, CAN HALİL, AKKOÇ TUNÇ,KARAÖZ ERDAL (2025). Feasibility of allogeneic mesenchymal stem cells in pediatric hypoxic-ischemic encephalopathy: Phase I study. World J Stem Cells, Doi: 10.4252/wjsc.v13.i5.470 (Yayın No: 9756414)
• 21-  KAPLAN NECATİ,KABATAŞ SERDAR,CİVELEK ERDİNÇ,Savrunlu Eyüp Can, AKKOÇ TOLGA,BOYALI OSMAN,ÖZTÜRK EREK, CAN HALİL, KARAÖZ ERDAL (2025). Multiroute administration of Wharton’s jelly mesenchymal stem cells in chronic complete spinal cord injury: A phase I safety and feasibility study. . World journal of stem cells, 5(17), 1-19., Doi: 10.4252/wjsc.v17.i5.101675,10.4252/wjsc.v17.i5.101675] (Yayın No: 9756074)

Articles published in other international refereed journals:

• 1- The rate of spondylodiscitis in patients with lomber discectomy using single dose prophylactic antibiotics. Diren Furkan; Can Halil; Onal Mehmet Bülent; Kırcelli Atilla. Journal of Academic Research in Medicine . Dec2019, Vol. 9 Issue 3, p1-18. 18p.
• 2-  Posterolateral Transcambın Approach For Surgıcal Treatment Of Thoracolomber Dısc Hernıatıons/Torakolomber Bıleske Dısk Hernıasyonlarının Cerrahı Tedavısınde Posterolateral Transkambın Yaklasım. Can Halil and Furkan Diren. J Ist Faculty Med 2020;83(3):227-33.
• 3- Lateral Mıcrosurgıcal Approach Performed Wıth Medıan Incısıon Wıthout Openıng Intertransverse Fascıa For Patıents Wıth L5-S1 Far Lateral Dısc Hernıatıon: A Retrospectıve Evaluatıon Of 12 Patıents. : Can H, Gomleksiz C. J Ist Faculty Med 2020;83(1):42-8.
• 4- Mınımal Superıor Artıcular Process Removal Of Facet Joınt In Lateral Interpedıcular Approach Could Provıde A Better Exposure In Far Lateral Dısc Hernıatıon Treatment: A Technıcal Report. Halil CAN, Atilla KIRCELLİ. J Turk Spinal Surg 2020;31(1):18-23.
• 5- Recurrent Laryngeal Nerve Palsy After Cervıcal Spıne Surgery Can Be Prevented. Hüseyin DOĞU, Halil CAN. J Turk Spinal Surg 2020;31(1):32-5.
• 6- Examination of Pons-Cerebellum Cisterna Anatomy by Endoscopic Retrosigmoid Suboccxipital Approach: Cadaveric Study.  Diren F, Gayretli Ö, Can H, Gürses İA, Barlas O. JAREM 2019; 9(3): 140-7.
• 7- The Motıon Range Of The Conus Medullarıs Movement Wıth Serıal Magnetıc Resonance Imagıng In Supıne And Prone Posıtıons: Results Of Fourty Healthy Subjects.  Gömleksiz C, Yaka U, Can H, Yörükoğlu HC, Göker B, Aydoseli A, et al. J Ist Faculty Med 2019;82(1):12-7.
• 8- Microsurgery Results in Vestibular Schwannoma Patients: Retrospective Clinical Study.  Can H, Dolgun M, Özgen U, Gömleksiz C, Diren F, Aydoseli A, et al. JAREM 2019; 9(2): 80-5.
• 9- İntrakranyal Hemanjiyoblastomlar: 32 Hastanın Klinik Değerlendirilmesi.  Tufan CANSEVER, Aykut KARASU, Kemal HEPGÜL, Halil CAN, Altay SENCER. Türk Nöroşirürji Dergisi, 2007, Cilt: 17, Sayı: 1, 8-14.

• APPROACH TO HEAD TRAUMA, Chapter Name: (COMA SCALES IN HEAD TRAUMA) (2019)., CAN HALİL, KARİNA Publishing House, Editor: Serdar Kabataş, Erdinç Civelek, Cem Yılmaz, Number of Editions: 1, Number of Pages: 204, ISBN: 978-605-7603-97-5, Turkish (Scientific Book) (Publication Number: 6117085)
• INTERVERTEBRAL DISC REGENERATION FROM DEGENERATIVE CASCADE TO MOLECULAR THERAPY, Chapter Name: (INTERVERTEBRAL DISC PATHOPHATHOLOGY) (2019)., CAN HALİL, SAGE PUBLISHING, Editor: DUYGU YAŞAR ŞİRİN, NUMAN KARAARSLAN, İBRAHİM YILMAZ, NECATİ KAPLAN, Number of Editions: 1, Number of Pages: 295, ISBN: 978-605-184-181-6, Turkish (Scientific Book) (Publication Number: 6118881)
• OSTEOPOROTIC SPINE, Chapter Name: (JUVENILE OSTEOPOROSIS - OSTEOGENESIS IMPERFECTA AND ITS SURGICAL TREATMENT) (2016)., ÖZTÜRK HATİCE, CAN HALİL, CİVELEK ERDİNÇ, REKMAY PUBLISHING, Editors: SERDAR KAHRAMAN, İ.TEOMAN BENLİ, Number of Editions: 1, ISBN: 978-975-6813-97-3, Turkish (Scientific Book) (Publication Number: 6062675)

• CAN HALİL,DÖLEN DUYGU (2019). PSÖDO TÜMÖR SEREBRİ TANISIYLA UNİLATERAL ENDOSKOPİK OPTİK  SİNİR DEKOMPRESYONU YAPILAN HASTALARIN RETROSPEKTİF DEĞERLENDİRİLMESİ: 11VAKA. Kafa Tabanı Derneği 4. Bilimsel Kongresi (Özet Bildiri/Sözlü Sunum) (Yayın No: 6071947)
• CAN HALİL (2019). TORAKOLOMBER DİSK HERNİASYONLARININ CERRAHİ TEDAVİSİNDE  POSTEROLATERAL TRANSKAMBİN YAKLAŞIM. 15. SİNİR SİSTEMİ CERRAHİSİ DERNEĞİ, 1(107) (Özet Bildiri/Sözlü Sunum) (Yayın No: 6072041)
• CAN HALİL,AYDOSELİ AYDIN (2019). PONS KAVERNOMLARININ SUBOKSİPİTAL KRANİYEKTOMİYLE  REZEKSİYONU. 33.TÜRK NÖROŞİRÜRJİ DERNEĞİ, 29(2), 1-477. (Özet Bildiri/Sözlü Sunum) (Yayın No:  6072068)
• CAN HALİL, KIRCELLİ ATİLLA (2018). Anterior Lomber Omurga Cerrahisinde Nörovasküler Risk: Anatomik  Çalışma. 32. Türk Nöroşirürji Derneği Kongresi, 28(1), 1-392. (Özet Bildiri/Sözlü Sunum) (Yayın No:  6071881)
• 5. KIRCELLİ ATİLLA,YILMAZ CEM ERİM,CANSEVER TUFAN,ÖZEL ÖMER, CAN HALİL, CİVELEK ERDİNÇ (2016).  Lomber Disk Hernilerinde Kaudal ve Transforaminal Epidural Steroid Enjeksiyonlarının Birlikte  Kullanımının Kısa ve Uzun Dönem Tedavi Sonuçlarına Etkisi. Türk Nöroşirürji Derneği 30. Bilimsel  Kongresi, 26(2), 1-421. (Özet Bildiri/Sözlü Sunum) (Yayın No: 6071964)

Other publications:

• 1. Case Report, AYDOSELİ AYDIN, ÖZGEN UTKU, AKGÜL TURGUT, KOCASOY ORHAN ELİF, ADIYAMAN ALI EKREM, CAN HALİL, KARADAĞ CIHAT (2019). Subacute Traumatic Ascending Myelopathy in a 28-Year-Old Man: A Rare Case. World Neurosurgery, 128, 143-148. (Publication No: 6070485)