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Last Updated on November 25, 2025 by
Peyronie’s disease is a condition where hard scar tissue forms in the penis, causing curvature. The exact cause remains unclear, but effective treatments are now available.
We are witnessing a significant advancement with the introduction of Xiaflex injections, a non-surgical alternative. Xiaflex, or collagenase clostridium histolyticum (CCH), targets the fibrous plaque causing penile curvature, giving patients new hope.
At Liv Hospital, we deliver world-class healthcare with full international patient support. Our goal is to use the most advanced therapies for Peyronie’s disease. This helps patients regain both function and confidence.
Peyronie’s disease is a condition that affects men. It causes scar tissue, or fibrous plaque, in the penis. This leads to symptoms like penile curvature, erectile dysfunction, and pain. Healthcare providers focus on understanding causes and symptoms to offer the right care.
The exact cause of Peyronie’s disease is not known. But, it’s thought to start from penis trauma or injury. This trauma leads to fibrous plaque, causing the penis to curve or bend. This plaque is a key factor in Peyronie’s disease and is vital for finding effective treatments.
Symptoms of Peyronie’s disease vary but often include penile curvature, erectile dysfunction, and pain during erection. The curvature can make sexual intercourse difficult or impossible. Some men also experience a shortening or narrowing of the penis. These symptoms can affect a man’s self-esteem and relationships.
Men with Peyronie’s disease symptoms should seek medical help. Early treatment can help manage symptoms and improve outcomes. We advise men to see a healthcare provider if symptoms persist or worsen. Advanced treatments like Xiaflex injections can help improve curvature and symptoms.
Understanding Peyronie’s disease causes and symptoms is the first step towards effective treatment. This can greatly improve a man’s quality of life.
Xiaflex ® is a big step forward in treating Peyronie’s disease without surgery. It helps patients get better results. This new treatment goes straight to the heart of the problem, giving people a choice other than surgery.
Collagenase Clostridium Histolyticum (CCH), known as Xiaflex ®, is a special enzymatic treatment. It breaks down the collagen that causes Peyronie’s disease. By injecting CCH into the plaque, we can lessen the bend and boost penile function.
Studies have shown that CCH is safe and works well. Xiaflex ® is a non-surgical option for men who don’t want surgery.
Xiaflex ® breaks down collagen in the plaque, reducing penile bend. It involves injections into the plaque and a procedure to fix the shape. This helps restore the penis to its normal shape.
Our clinical experience shows Xiaflex ® not only fixes the bend but also makes patients happier and more satisfied with their lives. It tackles the root cause of the problem, making it a more complete solution.
Xiaflex ® has FDA approval for treating Peyronie’s disease. This shows it’s safe and effective. The FDA based its approval on trials that showed big improvements in bend for treated patients.
More research supports Xiaflex ® as a top choice for Peyronie’s disease. We’re always looking for the latest in medical science to give our patients the best care.
With Xiaflex ®, patients can see up to 60% less bend when used with penile traction therapy. This makes it a strong alternative to surgery.
The modern Xiaflex treatment has changed how we manage Peyronie’s disease. It combines advanced medicine with special exercises. This has greatly improved how well patients do.
Our treatment includes a 4-cycle injection process. Each cycle is followed by exercises and stretching at home. This method helps Xiaflex work better by breaking down plaque and straightening the penis.
The first part of the treatment involves three visits, each 24 to 72 hours apart. Studies show adding penile traction and stretching can greatly improve penis shape.
Penile traction therapy is key in our treatment. It helps straighten the penis and makes Xiaflex injections more effective. We teach patients how to use the device for the best results.
Using penile traction with Xiaflex injections improves treatment results. This method helps correct more curvature and makes patients happier with their treatment.
Patients will get injections, do exercises, and have therapy sessions. We help them understand each step and how to get the best results.
Following the treatment plan closely is important for the best results. Our team supports patients, helping them overcome any challenges and recover well.
For those looking to fix curvature at home, our treatment includes exercises to do at home. This helps patients be more involved in their recovery.
Xiaflex is a game-changer for Peyronie’s disease, backed by solid evidence. It has greatly helped patients, often when used with other treatments.
Research shows a 20 to 60 degree curvature drop. This depends on the disease’s severity and treatment. Such a reduction can significantly enhance a patient’s life quality.
Studies reveal a 50% to 60% curvature improvement with Xiaflex and penile traction. This combo therapy is showing great promise in trials.
Choosing the right patient for Xiaflex is key. We look at each patient’s condition and health to decide if Xiaflex is right for them.
Though Xiaflex is the only FDA-approved injectable for Peyronie’s, we explore other options too. These alternatives offer hope for those not suited for Xiaflex.
Best candidates for Xiaflex have curvatures between 30 and 90 degrees. We evaluate each patient to find the best treatment plan for them.
Our experience shows that the right treatment can lead to big improvements. We’re dedicated to top-notch care and support for those with Peyronie’s disease.
We are committed to improving care for Peyronie’s disease patients. At Liv Hospital, we aim to make a difference in our patients’ lives. We offer top-notch healthcare and support every step of the way.
A disease expert stresses the need to share all treatment options with patients. This includes new therapies like Xiaflex ®. For more details, visit the National Center for Biotechnology Information resources.
We focus on the latest treatments and patient-centered care. Our goal is to enhance the lives of those with Peyronie’s disease. We want to give our patients the knowledge and support they need, ensuring they get the best care possible.
Peyronie’s disease is a condition where fibrous plaque forms in the penis. This leads to curvature and other symptoms. It can greatly affect a person’s quality of life.
The exact cause of Peyronie’s disease is not known. But it’s thought to come from injury or trauma to the penis. This injury leads to the formation of fibrous plaque.
Symptoms include penile curvature, pain, and trouble with erections. The curvature can be severe. It causes distress and affects sexual function.
Peyronie’s disease is treated in several ways. These include Xiaflex injections, penile traction therapy, and surgery. Xiaflex is a non-surgical option that has shown good results in studies.
Xiaflex is an injectable treatment for Peyronie’s disease. It targets the fibrous plaque causing curvature. It breaks down the plaque, helping to straighten the penis.
The Xiaflex treatment involves a 4-cycle injection process. Each cycle is followed by penile traction therapy and stretching exercises at home. This maximizes the treatment’s effectiveness.
Xiaflex significantly improves penile curvature. Patients can see up to 60% improvement when used with penile traction therapy.
Yes, Xiaflex is the only FDA-approved injectable treatment for Peyronie’s disease. This shows it is both effective and safe.
Yes, there are other treatment options for those not suited for Xiaflex. These are chosen on a case-by-case basis.
Your suitability for Xiaflex is determined by a careful evaluation. This considers the severity of curvature and your overall health.
During Xiaflex treatment, you’ll undergo injections, followed by penile traction therapy and stretching exercises at home. Our healthcare team will guide you. They’ll help you understand what to expect and how to get the best results.
Levine, L. A., Cuzin, B., Mark, S., et al. (2015). Clinical safety and effectiveness of collagenase clostridium histolyticum injection in patients with Peyronie’s disease: A phase iii open-label study. The Journal of Sexual Medicine, 12(1), 248-258. https://doi.org/10.1111/jsm.12790
Mefford, A. T., & Colleagues. (2021). Peyronie’s disease “ outcomes of collagenase clostridium histolyticum treatment: Results from a real-world registry study. Translational Andrology and Urology, 10(3), 1276-1284. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451611/
