Research
1. Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to to Diabetic Macular Edema (RESTORE); Randomized, double-masked, multicenter, laser-controlled Phase III study, Assignment: Principal Investigator, 2009-2011; Principal Investigator: 2011-2012.
2. A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment duration study evaluating the efficacy and safety of Siponimod (BAF312) in patients with secondary progressive multiple sclerosis (EXPAND). Duties: Researcher Specialist Dr, 2013-2015.
International Study Participant Expert Dr:1. The European Vitreo-Retinal Society Retinal Detachment Study (2011)
A. Strategy for the Management of Uncomplicated Retinal Detachments;
B. Strategy for the Management of Complex Retinal Detachments.
2. The European Vitreo-Retinal Society Endophthalmitis Study (2018)
3. The European Vitreoretinal Society central serous chorioretinopathy study (2019)
4. Turkish ERM Study Group. Relation of anatomy with function following the surgical treatment of idiopathic epiretinal membrane: a multicenter retrospective study (2021)
A1. E. Toker, H. Kazokoğlu ve N. Acar, “High dose intravenous steroid therapy for severe posterior segment uveitis in Behçet's disease”, Br J Ophthalmol, 86(5):521-3 (2002).
A2. N. Acar, E. Toker ve H. Kazokoğlu, “Tear and serum eosinophil cationic protein levels in seasonal allergic conjunctivitis”, Eur J Ophthalmol, 13(8):671-5 (2003).
A3. Bayraktar, Z., Kapran, Z., Bayraktar, S., Acar, N., Unver, YB. ve Gök, K. “Delayed-onset streptococcus pyogenes endophthalmitis following Ahmed glaucoma valve implantation”, Jpn J Ophthalmol, 49(4):315-7 (2005).
A4. Kapran, Z., Utine, CA., Gungel, H., Acar, N., ve Perente, I. “Complicated retinal detachment in a case with gyrate atrophy”, Ophthalmologia, 18(3):248-251, (2006).
A5. Kapran, Z. ve Acar, N. “Removal of silicone oil with 25-gauge transconjunctival sutureless vitrectomy system”, Retina, 27(8):1059-64 (2007).
A6. Acar, N., Kapran, Z., Utine, CA. ve Büyükbabani, N. “Pars plana vitrectomy revealed Toxocara canis organism”, Int Ophthalmol, 27(4):277-80 (2007).
A7. Kapran, Z ve Acar, N. “Active removal of silicone oil with 25-gauge sutureless system”, Retina, 27(8), 1133-5 (2007).
A8. Acar, N., Unver, Y.B., Altan, T. ve Kapran, Z. “Acute endophthalmitis after 25-gauge sutureless vitrectomy”, Int Ophthalmol, 27(6):361-3, (2007).
A9. Acar, N., Kapran, Z., Unver, YB., Altan, T ve Ozdogan, S., “Early Postoperative Hypotony Following 25-Gauge Sutureless Vitrectomy With Straight Incisions”, Retina, 28(4):545-52 (2008).
A10. Scott, I.U., Flynn, HW. Jr., Dev, S., Shaikh, S., Mittra, R.A., Arevalo, JF., Kychenthal, A. ve Acar, N. “Endophthalmitis after 25-gauge and 20-gauge pars plana vitrectomy: incidence and outcomes”, Retina, 28(1), 138-42 (2008).
A11. Cakir, M., Dogan, M., Bayraktar, Z., Bayraktarm S., Acar, N., Altan, T., Kapran, Z. ve Yilmaz, OF. “Efficacy of intravitreal triamcinolone for the treatment of macular edema secondary to branch retinal vein occlusion in eyes with or without grid laser photocoagulation”, Retina, 28(3):465-72, (2008).
A12.Kapran, Z., Altan, T., Acar, N., ve Unver, YB. “Triamcinolone applicator cannula”, Retina, 28(5):770-1, (2008).
A13. Altan, T., Acar, N., Kapran, Z., Unver, YB. Ve Ozdogan, S. “ Transconjunctival 25-gauge sutureless vitrectomy and silicone oil injection in diabetic tractional retinal detachment”, Retina, 28 (9), 1201-1206 (2008).
A14. Kapran, Z., Acar, N., Unver, YB., Altan, T. ve Ocak, B. “Passive removal of silicone oil with a 25-gauge sutureless system”, Jpn J Ophthalmol., 52(1):63-6, (2008)
A15. Acar, N., Kapran, Z., Altan, T., Unver, YB., Yurtsever, S., ve Kucuksumer, Y., “ Primary 25-gauge sutureless vitrectomy with oblique sclerotomies in pseudophakic retinal Detachment”, Retina, 28(8), 1068-74 (2008).
A16. Unver, YB., Acar ,N., Kapran, Z., ve Altan, T. “Visual predictive value of the ocular trauma score in children”, Br J Ophthalmol, 92(8):1122-4, (2009).
A17. Unver, YB., Kapran, Z., Acar, N., ve Altan, T. “Ocular trauma score in open-globe Injuries”, J Trauma, 66(4):1030-2, (2009).
A18. Unver, YB., Acar ,N., Kapran, Z., ve Altan, T. “Results and prognostic factors in severely traumatized eyes with posterior segment involvement”, Ulus Journal of Trauma Emergency Surgery, 15(3): 271-76 (2009).
A19. Kapran, Z., Acar, N., Altan, T., Unver, YB., ve Yurtsever, S. “25-gauge Sutureless Vitrectomy with Oblique Sclerotomies for the Management of Retinal Detachment in Pseudophakic and Phakic Eyes”, European J Ophthalmol, 19(5):853-60, (2009).
A20. Acar, N., Unver, YB., Kapran, Z. ve Altan, T. “Removal of Large Subretinal Foreign Bodies With Bimanual Vitrectomy and the Use of a Suture Loop”, Retinal Cases and Brief Reports ;3(4):347-50, 2009.
A21. Unver, YB., Acar, N., Kapran, Z.ve Altan, T. “25-gauge sutureless vitrectomy in Osteogenesis Imperfecta Type I”, Retinal Cases and Brief Reports, 3(3):286-7. (2009).
A22. Altan, T., Acar, N., Kapran, Z., Unver ,YB., Yurttaser, S., Küçüksümer, Y. ve Eser, I. “ Acute-onset endophthalmitis after cataract surgery: success of initial therapy, visual outcomes, and related factors”, Retina; 29(5): 606-12 (2009).
A23. Altan, T., Kapran, Z., Eser, I., Acar, N., Unver, YB., Yurttaser, S. “Comparative outcomes of pars plana vitrectomy in acute postoperative endophthalmitis with 25-gauge and 20-gauge techniques.” Jpn J Ophthalmol,; 53(5):506-11. (2009).
A24. Acar, N.,Kapran, Z., Altan, T., Kucuksumer, Y., Unver, Y.B., Polat E., “Secondary Iris Claw Intraocular Lens Implantation for the Correction of Aphakia Following Pars Plana Vitrectomy”, Retina, 30(1):131-9 (2010).
A25. Acar N, Kapran Z, Altan T, Unver YB, Pasaoglu E. “Pars plana vitrectomy with and without triamcinolone acetonide assistance in pseudophakic retinal detachment complicated with proliferative vitreoretinopathy.” Jpn J Ophthalmol. 2010;54(4):331-7.
A26. Scott IU, Flynn HW Jr, Acar N, Dev S, Shaikh S, Mittra RA, Arevalo JF, Kychenthal A, Kunselman A. “Incidence of endophthalmitis after 20-gauge vs 23-gauge vs 25-gauge pars plana vitrectomy.” Graefes Arch Clin Exp Ophthalmol. 2011; 249(3): 377-380.
A27. Altan T, Acar N, Kapran Z, Unver YB, Ozdogan S. “Outcome of photodynamic therapy in choroidal neovascularization due to pathologic myopia and related factors.” Int Ophthalmol. 2012; 32(2):119-25.
A28. Adelman RA, Parnes AJ, Ducournau D; “European Vitreo-Retinal Society (EVRS) Retinal Detachment Study Group. Strategy for the management of uncomplicated retinal detachments: the European vitreo-retinal society retinal detachment study report 1.” Ophthalmology. 2013;120(9):1804-8.
A29. Adelman RA, Parnes AJ, Sipperley JO, Ducournau D; “European Vitreo-Retinal Society (EVRS) Retinal Detachment Study Group. Strategy for the management of complex retinal detachments: the European vitreo-retinal society retinal detachment study report 2.” Ophthalmology. 2013;120(9):1809-13.
A30. Adelman RA, Parnes AJ, Michalewska Z, Ducournau D; “European Vitreo-Retinal Society (EVRS) Retinal Detachment Study Group. Clinical variables associated with failure of retinal detachment repair: the European vitreo-retinal society retinal detachment study report number 4.” Ophthalmology. 2014;121(9):1715-9.
A31. Tugcu B, Acar N, Coskun CT, Celik S, Yigit FU. “Nonarteritic anterior ischemic optic neuropathy as the presenting manifestation of primary antiphospholipid syndrome. Indian J Ophthalmol. 2014;62(5):642-4.
A32. Acar N. A NEW DESIGN INTRAOCULAR FOREIGN BODY FORCEPS. Retina. 2017 Oct 9. doi: 10.1097/IAE.0000000000001839. [Epub ahead of print] PubMed PMID: 29016450.
A33. Tugcu B, Nacaroglu SA, Gedikbasi A, Uhri M, Acar N, Ozdemir H. Protective effect of pomegranate juice on retinal oxidative stress in streptozotocin-induced diabetic rats. Int J Ophthalmol. 2017 18;10(11):1662-1668.
A34. Pehlivanoğlu S, Acar N, Albayrak S, Karakaya M, Ofluoğlu A. The assessment of autofluorescence of the crystalline lens in diabetic patients and healthy controls: can it be used as a screening test? Clin Ophthalmol. 2018 27;12:1163-1170.
A35. Soliman MK, Gini G, Kuhn F, et al; European Vitreo-Retinal Society Endophthalmitis Study Group. International Practice Patterns for the Management of Acute Postsurgical and Postintravitreal Injection Endophthalmitis: European Vitreo-Retinal Society Endophthalmitis Study Report 1. Ophthalmol Retina. 2019 ;3(6):461-467.
A36. Michalewska Z, Adelman R, Bonovas S, Bopp S; EVRS study group. An international collaborative evaluation of central serous chorioretinopathy: different therapeutic approaches and review of literature. The European Vitreoretinal Society central serous chorioretinopathy study. Acta Ophthalmol. 2019 Dec 6. doi: 10.1111/aos.14319. Epub ahead of print.
A37. Ozdek S, Ozdemir Zeydanli E, et al: Turkish ERM Study Group. Relation of anatomy with function following the surgical treatment of idiopathic epiretinal membrane: a multicenter retrospective study. Graefes Arch Clin Exp Ophthalmol. 2021 ;259(4):891-904. Erratum in: Graefes Arch Clin Exp Ophthalmol. 2021 Feb 24; PMID: 33185727.
A38. Soliman MK, Gini G, Kuhn F, et al; European Vitreo-Retinal Society (EVRS) Endophthalmitis Study Group. VISUAL OUTCOME OF EARLY VITRECTOMY AND INTRAVITREAL ANTIBIOTICS IN ACUTE POSTSURGICAL AND POSTINTRAVITREAL INJECTION ENDOPHTHALMITIS: European Vitreo-Retinal Society Endophthalmitis Study Report Two. Retina. 2021 Feb 1;41(2):423-430.
A39. Acar N, Celiker P. Intravitreal Chopping of Dropped Nucleus with a Nitinol Intraocular Foreign Body Forceps: An Alternative Technique for the Management of Retained Nucleus Fragments. Retina. 2022 Mar 17. doi: 10.1097/IAE.0000000000003476. Epub ahead of print.
A40. Toker, E., Acar, N., and Öğüt, M. S., "The Relationship of Amblyopia Depth with the Amount of Anisometropia", MN Ophthalmology, 6: 66-68 (1999).
A41. Toker, E., Acar, N., Öğüt, M. S., Bavbek, T., and Alper, G., "Ophthalmic Findings in Joubert Syndrome", T Oft Gaz; 29: 269:274 (1999).
A42. Acar, N., Toker, E., and Kazokoglu, H., "The Place of High Dose Intravenous Steroid Therapy in Severe Posterior Segment Attack of Behçet's Disease", T Oft Gaz; 30: 501-504 (2001).
A43. Toker, E., Acar, N., and Öğüt, M. S., "Case Report: Sebaceous Gland Carcinoma with Lid Mass: Chalazion? Carcinoma?", T Oft Gaz; 31: 548-552 (2001).
A44. Toker, E., Acar, N., and Kazokoglu, H., "Efficacy of topical 0.1% Cyclosporine A treatment in dry eye disease due to Sjögren's Syndrome", T.Oft.Gaz; 33:324-330 (2003).
A45. Bayraktar, Z., Utine, C.A., Kapran, Z., Altan, T., Acar, N., Ünver, Y.B., Çakır, M., and Pınarcı, E.Y., "Comparison of the Largest Lesion Diameters Measured by FA and ISYVA in Patients with AMD with Subfoveal Neovascular Membrane", Ret-Vit; 13:193-196 (2005).
A46. Acar, N., Kapran, Z., Ünver, Y.B., Kayaarası, Z., Bayraktar, Z., and Çakır, M., "Anterior Hyaloidal Fibrovascular Proliferation after Vitrectomy in Patients with Proliferative Diabetic Retinopathy", Retina-Vitreus;13(2):107-113 (2005).
A47. Kapran, Z., Acar, N., Ünver, Y.B., Karakaya, M., Çakır, M., and Bayraktar. Z., "First Results with 25-Gauge Transconjunctival Sutureless Vitrectomy Technique", Retina-Vitreus:13:183-188 (2005).
A48. Ünver, Y.B., Acar, N., Kapran, Z., Ağca, A., Çakır, M., and Bayraktar, Z., "Vitreoretinal surgery in ocular trauma associated with traumatic lens dislocation/subluxation", Retina-Vitreus;13(3):205-209 (2005).
A49. Bayraktar, Z., Akalan, H., Kapran, Z., Altan, T., Acar, N., Ünver, Y.B., and Utine, C.A., "Comparison of fluorescein angiography and indocyanine green videoangiography findings in age-related macular degeneration", Retina-Vitreus;13(1):53-56 (2005).
A50. Bayraktar, Z., Kapran, Z., Mete, M., Altan, T., Acar, N., and Ünver, Y.B., "Indications and Results of Pars Plana Vitrectomy in Pediatric Age Group", Retina-Vitreus;13(4):283-287 (2005).
A51. Bayraktar, Z., Kapran, Z., Utine, C.A., Altan, T., Acar, N., and Güngel, H., "Pars plana vitrectomy in tractional diabetic macular detachment", Göztepe Medical Journal;20(1):7-10, 2005.
A52. Bayraktar, Z., Oral, O., Kapran, Z., Pinarci, E.Y., Altan, T., Acar, N., Unver, Y.B., and Cakir, M., "Vitreoretinal surgery in posterior segment complications due to chronic uveitis", Retina-Vitreus;13(2):89-93 (2005).
A53. Bayraktar, Z., Kapran, Z., Altan, T., Acar, N., and Ünver, Y.B., "In vitreous injection of triamcinolone in diffuse macular edema due to vascular diseases of the retina", T.Oft Gaz;35:239-242 (2005).
A54. Acar, N., Kapran, Z., Ünver, Y.B., and Bayraktar, Z., "Surgical Removal of Idiopathic Peripapillary Subretinal Membrane", Retina-Vitreus; 13;7-10 (2005).
A55. Unver, Y.B., Kapran, Z., Acar, N., Cakir, M., Bayraktar, Z., Yilmaz, O.F., "Penetrating Keratoplasty and Vitreoretinal Surgery with Temporary Prosthesis", Retina-Vitreus; (13):39-42 (2005). (Special issue)
A56. Çakır, M., Kapran, Z., Altan, T., Acar, N., Ünver, Y.B., Bayraktar, Z., Perente, I., Utine, C.A., "Subretinal tissue plasminogen activator (t-PA) and pneumatic displacement in submacular hemorrhage", Retina-Vitreus; (13):19-21 (2005). (Special issue)
A57. Altan, T., Kapran, Z., Yalcin, O., Acar, N., Cakir, M., and Unver, Y.B., "Mid- and long-term results of photodynamic treatment of subfoveal choroidal neovascularization with verteporfirin in age-related macular degeneration", Retina-Vitreus;14(3):169-174 (2006).
A58. Çakır, M., Kapran, Z., Başoğlu, A., Acar, N., Ünver, Y.B., Altan T., Bayraktar, Z., Perente, I., and Utine, C.A., "Anatomical and Functional Results of Vitrectomy and Internal Limiting Membrane Peeling in the Treatment of Stage 3 and 4 Macular Hole", Retina-Vitreus;14(2):109-114 (2006).
A59. Cerman, E., Yenice, O., Kazokoglu, H., Elbir, Y., and Acar, N., "Serum and vitreous leptin and VEGF levels in diabetic retinopathy cases", Retina-Vitreus;15(1):21-26, 2007.
A60. Altan, T., Acar, N., Ünver, Y.B., Özdoğan, S., Kapran, Z., and Küçüksümer, Y., "Monitoring of Subfoveal Fluid with Optical Coherence Tomography in a Case with Sympathetic Ophthalmia During the Treatment Process", Retina-Vitreus, 16(4): 307-10 (2008).
A61. Kapran, Z., Acar, N., "Treatment of Proliferative Diabetic Retinopathy", Retina-Vitreus, 16(2):85-90 (2008).
A62. Altan, T., Acar, N., Kapran, Z., Ünver, YB., Özdogan, S. and Küçüksümer, Y., "Results of radial optic neurotomy with or without intravitreal triamcinolone for central retinal vein occlusion", Retina-Vitreus,16(2):101-106 (2008).
A63. Altan, T., Acar, N., Ünver, YB., Eser, I. and Kapran, Z., "Pathogens in endophthalmitis following cataract surgery", T Oft Gaz;38(3): 204-207 (2008).
A64. Altan, T., Ovalı, F., Eser, İ., Uysal, S., Acar, N., Enver, A., Unver, YB. and Kapran, Z., "Prevalence of retinopathy of prematurity and associated factors in infants screened in neonatal intensive care unit", Retina-Vitreus, 16(2):101-106 (2008).
A65. Alkın, Z., Acar, N., Altan, T., Ünver, Y.B., Sabancı, Ş., Küçüksümer Y. and Kapran, Z., "Treatment of Retinal Detachments in Cases with Refractive Lens Exchange and Phakic Intraocular Lens Implantation", Retina-Vitreus, 17(1):42-47 (2009).
A66. Acar, N., Kapran, Z., Altan, T., Unver, Y.B., Yurttaser, S. "Comparison of 25-gauge Sutureless Vitrectomy and 20-gauge Vitrectomy Techniques in the Treatment of Diabetic Vitreous Hemorrhage", Retina-Vitreus, 17 (2) : 101-107 (2009).
A67. Acar, N., Kapran, Z., Altan, T., Unver, Y.B., Yurttaser, S., "Results of Combined 25-Gauge and 20-Gauge Pars Plana Vitrectomy Technique", Retina-Vitreus, 17(2): 125-130 (2009).
A68. Alkın, Z., Kapran, Z., Altan, T., Uzun, E., Acar, N., Ünver, YB., "Photodynamic Therapy Results in the Treatment of Chronic Central Serous Chorioretinopathy", Retina-Vitreus, 18(1):23-28 (2010).
A69. Alkın, Z., Kapran, Z., Altan, T., Küçüksümer Y, Acar, N., Ünver, YB., "Isolated bilateral blow-out fracture: A case report", Türkiye Klinikleri Oftalmoloji Dergisi, 19(3):185-188 (2010).
A70. Alkın, Z., Kapran, Z., Altan, T., Ünver, YB., Acar, N. "Unusual Ocular Presentation of Von Hippel-Lindau Disease", Retina-Vitreus, 18(1):314-317 (2010).
A71. Acar N. `Branch Retinal Vein Occlusion and Hemispheric Occlusion', Türkiye Klinikleri, Retinal Vascular Diseases, Special Issue; 4(3):40-50 (2011).
A72. Ozkaya A, Ünver, YB., Acar, N., Kapran, Z. "Fundus Imaging Findings in Two Cases of Type 2a Juxtafoveal Retinal Telangiectasia", Retina-Vitreus, 20(2):146-150 (2012).
A73. Acar N., "Is pharmacotherapy effective in the prophylaxis of proliferative vitreoretinopathy?" Retina-Vitreus, 21(3); 166-177 (2013).
A74. Acar N., "Clinical Results in Visual Prosthesis and Current Status" Retina-Vitreus, 28(4); 339-348 (2019).