About Liv

Why No PSA Test After 75? | PSA Levels by Age

Last Updated on October 31, 2025 by

Why No PSA Test After 75? | PSA Levels by Age
Why No PSA Test After 75? | PSA Levels by Age 4

As men get older, the need for Prostate-Specific Antigen (PSA) tests is debated. Experts now say not to test men over 75 regularly. This change is because most prostate cancers in older men grow slowly and don’t shorten their lives.

Choosing to get a PSA test is a big decision that depends on a man’s health and personal preferences. The US Preventive Services Task Force advises against screening for men over 75, citing concerns about treating cancers that may not cause significant harm. Understanding psa levels by age is important in making an informed choice.

Key Takeaways

  • Current guidelines recommend against routine PSA screening for men over 75.
  • Most prostate cancers in men over 75 are indolent and slow-growing.
  • The decision to undergo PSA screening should be based on individual health and preferences.
  • Overtreatment is a concern with PSA screening in older men.
  • Health systems like Liv Hospital champion evidence-based, patient-first care.

The Basics of PSA Testing and Prostate Cancer Screening

Why No PSA Test After 75? | PSA Levels by Age
Why No PSA Test After 75? | PSA Levels by Age 5

The PSA test is a simple blood test that checks for prostate-specific antigen. This protein is found in both healthy and cancerous prostate cells. Knowing how PSA testing works helps men make smart choices about their health.

What is a PSA Test and How It Works

A PSA test is a key tool for finding prostate cancer early. It looks at the PSA levels in your blood. High levels might mean cancer, but they can also show other issues like prostatitis or BPH.

As the National Cancer Institute’s fact sheet notes, the test isn’t perfect. It can’t always be told if a high PSA means cancer. If your PSA is high, you might need more tests, like a biopsy, to find out why.

Talking to your doctor about your PSA test results is important. They can help you understand what the numbers mean and what to do next.

Historical Use of PSA Screening in Prostate Cancer Detection

PSA screening started in the late 1980s. It’s now a key way to find prostate cancer early. This has helped doctors treat cancer when it’s easier to cure. But the test isn’t perfect and can lead to false positives and finding slow-growing cancers.

Even with its flaws, PSA testing is valuable. Men should know its limits and talk to their doctors about their risks. This way, they can decide how often to get their prostate checked.

PSA Levels by Age: What’s Considered Normal and Concerning

Why No PSA Test After 75? | PSA Levels by Age
Why No PSA Test After 75? | PSA Levels by Age 6

PSA test results change with age. As men get older, their PSA levels can go up. It’s key to use age-specific ranges to check prostate health.

Age-Specific PSA Reference Ranges

PSA levels differ by age. What’s normal for one age might be high for another. Here are some age-specific PSA ranges:

  • For men in their 40s, a PSA level below 1.5 ng/mL is normal.
  • For men in their 50s, a PSA level below 2.5 ng/mL is often normal.
  • For men in their 60s and 70s, levels above 4 ng/mL need more checking.

These are general guidelines. Individual factors can affect what’s normal for a certain age.

How PSA Levels Naturally Increase with Age

As men age, their prostate gets bigger. This can raise PSA levels. Also, the chance of prostate cancer goes up with age. But many cancers in older men are slow-growing and not dangerous.

Knowing normal PSA levels by age and PSA scores by age is key. It helps men and doctors make better choices about prostate health.

When looking at the PSA range by age, remember other factors too. These include prostate size, overall health, and family history of prostate cancer.

Reason #1: Most Prostate Cancers in Men Over 75 Are Indolent

PSA screening is not recommended after 75 because most prostate cancers in this age group are slow-growing. These cancers are not aggressive and do not harm the quality of life.

Slow-Growing Nature of Geriatric Prostate Cancer

Studies show that prostate cancer in older men grows slowly. Research indicates that many of these cancers would not cause symptoms or death even if untreated. This slow growth is why PSA screening is not recommended for men over 75.

The slow nature of these cancers means early detection through PSA screening is less beneficial. The risks of screening and treatment often outweigh the benefits.

Two-thirds of Detected Cancers Are Overdiagnosed

PSA screening in men over 75 leads to overdiagnosis of prostate cancer. Studies show that up to two-thirds of these cancers are overdiagnosed, meaning they would not harm if left undetected.

A well-known doctor noted, “Many of them would never have harmed the patient.” This shows that treating all prostate cancers aggressively is not always necessary. A more thoughtful approach is needed, considering the cancer’s growth rate and the individual’s age and health.

Key Points to Consider:

  • Prostate cancer in men over 75 is often indolent and slow-growing.
  • PSA screening can lead to overdiagnosis and unnecessary treatment.
  • The risks of screening and treatment may outweigh the benefits in this age group.

Understanding these factors is key to making informed decisions about prostate health and PSA screening as men age.

Reason #2: The Harms Outweigh the Benefits After 75

In men over 75, the downsides of PSA screening can be too much. This includes unnecessary anxiety and treatments. The US Preventive Services Task Force says the harms are greater than the benefits after 75.

Psychological Impact of False Positives and Diagnosis

A false-positive PSA test can cause a lot of worry in men. This worry can last even after tests show there’s no cancer. The emotional toll of a false-positive result should not be underestimated, as it can lead to unnecessary worry and fear about one’s health.

Also, being told you have prostate cancer can deeply affect you. Even if the cancer grows slowly, the fear of having cancer can be overwhelming. It can lead to anxiety, depression, and a change in how you see yourself.

Complications from Unnecessary Biopsies and Treatments

PSA screening can lead to biopsies to find prostate cancer. While biopsies are usually safe, they can cause pain, infection, and bleeding. In some cases, these complications can be severe, requiring hospitalization.

Also, finding prostate cancer through PSA screening might lead to treatments that aren’t needed. Many prostate cancers in older men grow slowly. Treatments like surgery and radiation can cause problems like urinary incontinence, erectile dysfunction, and bowel issues. These can greatly affect a man’s quality of life.

It’s important to understand the risks of PSA screening after 75. By knowing the risks and benefits, men and their doctors can make the best choices for their health.

Reason #3: Limited Life Expectancy Benefit in Men Over 75

Life expectancy is key when thinking about PSA screening for men over 75. Doctors stop PSA screening for men in this age group because they often don’t live long enough to benefit from it.

The 10-Year Life Expectancy Threshold

The American Urological Association says to stop PSA screening if a man’s life expectancy is less than 10 years. This rule helps doctors decide who will most likely benefit from early cancer detection.

For a 75-year-old man, knowing what a normal PSA level is important. Older men usually have higher normal PSA scores by age. But what’s normal for a 75-year-old can vary. Doctors look at how fast PSA levels change over time.

Impact of Comorbidities on Treatment Decisions

Other health problems, or comorbidities, also play a big role in treatment choices for older men. Conditions like heart disease or diabetes can make the benefits of PSA screening and treatment less clear.

Doctors look at a man’s overall health before deciding on PSA screening. For men with serious health issues, the risks of tests and treatments might be too high. This is true if they’re not expected to live more than 10 years.

In short, the limited life expectancy in men over 75 is a big reason to stop routine PSA screening. By understanding PSA by age and looking at each person’s health, doctors can make better choices. They aim to find the right balance between the benefits and risks of screening.

Current Practices and Exceptions to Consider

Recent studies show that many men over 75 get PSA screening, even when guidelines say not to. This shows how hard it is to apply general rules to each person’s health.

Despite Guidelines, 42% of Men Over 75 Still Receive Screening

About 42% of men aged 75 and up get PSA screening. This goes against guidelines for this age group. It shows we need a more detailed way to look at prostate health in older men.

Deciding on PSA screening for older men depends on their health, how long they might live, and what they want. Healthy older men with more than 10 years to live might get benefits from PSA screening.

When PSA Testing Might Still Be Appropriate After 75

Experts like Walsh say PSA surveillance might be right for very healthy older men. They think men who are likely to live long and are healthy could get early cancer detection and treatment benefits.

When thinking about PSA testing for men over 75, doctors should look at the patient’s health, any other health issues, and the good and bad sides of screening. This way, decisions are made with more information.

  • Look at the patient’s overall health and life expectancy.
  • Think about any other health problems that might affect treatment choices.
  • Talk about the good and bad sides of PSA screening with the patient.

Conclusion: Balancing Prostate Health and Quality of Life

When we talk about PSA testing for men over 75, it’s all about balance. It’s important to think about each person’s health and how long they might live. The choice to get a PSA test should be made carefully, considering these factors.

Knowing what’s normal for a 75-year-old man’s PSA level is key. PSA levels can change a lot with age. Some men might have high PSA levels, but how high is too high before it’s a sign of death? This depends on many things, like whether there’s cancer and the man’s overall health.

At Liv Hospital, we focus on preventive and ethical health care. We help men make informed choices about PSA screening. We make sure they get care that fits their unique needs and values.

In the end, we aim to improve the quality of life while dealing with prostate health issues. This way, men over 75 get care that’s right for them, based on their own situation.

FAQ

What is a normal PSA level for a man over 75?

For men over 75, what’s normal can be different. A PSA level below 4.0 ng/mL is usually okay. But, the exact range can vary based on age.

How often should a man have his prostate checked?

How often to check the prostate depends on several factors. These include risk, health, and age. For those over 75, regular PSA tests are not always needed unless there’s a high risk or good health with more than 10 years to live.

What is considered a dangerous PSA level by age?

A high PSA level is a concern, but what’s high can vary by age. For older men, even small increases might be a worry. But it’s all about overall health and other factors.

Are there any exceptions to not having a PSA test after 75?

Yes, some men over 75 might benefit from PSA tests. This includes those in good health with more than 10 years to live. The choice should be based on individual health and preferences.

What are the implications of a high PSA level?

A high PSA level might mean prostate cancer, but it could also be due to other issues. More tests, like a biopsy, are needed to find out the cause.

How do comorbidities affect treatment decisions for prostate cancer in older men?

Other health issues can greatly influence treatment choices for prostate cancer in older men. These conditions might lead to a more cautious approach, focusing on symptom management over aggressive treatment.

What is the psychological impact of false-positive PSA results?

False-positive PSA results can cause a lot of worry and stress. Men might face unnecessary biopsies and health concerns. This shows the importance of thinking carefully before getting a PSA test.

How do PSA levels naturally change with age?

PSA levels often go up with age, even without cancer. This is why age-specific ranges are used to understand PSA test results.

References

  1. U.S. Preventive Services Task Force. (2018). Prostate Cancer: Screening. Retrieved from https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening
  2. Janes, S. E., et al. (2020). Screening for prostate cancer in older men: A population-based study. Journal of Gerontology: Medical Sciences, 75(5), 999–1005. https://doi.org/10.1093/gerona/glaa045

Subscribe to Liv E-newsletter