A Guide to Cross-Matching for Kidney Transplant

Cross-matching checks donor–recipient compatibility before surgery. It helps predict rejection risk and guides safer, more successful transplants.

Why Matters

Early detection of incompatibilities lets clinicians tailor immunosuppression, lowering rejection risk and improving graft survival and patient outcomes.

Cross-Matching

Cross-Matching Explained

Donor cells are tested against the recipient’s serum to see if antibodies react. A negative cross-match suggests compatibility; a positive one signals risk.

Tissue Cross-Match (Cellular Level)

Analyzes HLA antigens on cell surfaces to spot immune mismatches. Results help personalize therapy and reduce the chance of cellular level rejection.

Blood Cross-Match (ABO/Rh)

Confirms ABO and when relevant, Rh compatibility. Prevents severe, immediate immune reactions during and after kidney transplantation.

Methods: From Classic to Cutting Edge Technology

Traditional complement dependent cytotoxicity meets modern flow cytometry and Luminex assays, boosting sensitivity, precision, and confidence.

Interpreting Results

Positive cross-match may call for enhanced immunosuppression or alternative donors. Negative results indicate lower rejection risk and better fit.

Technology Driving Precision

Advances in assay platforms refine antibody detection and risk prediction, supporting safer decisions and higher long term graft success.

The Patient Journey at Liv Hospital

Personalized evaluation, advanced labs and expert transplant teams in Istanbul.Clear guidance from testing to post transplant care.

Start Your Evaluation

Considering kidney transplant in Turkey? Contact Liv Hospital to discuss cross-matching, candidacy, and treatment options tailored to you.

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