Most nerve blocks last 8-24 hours, sometimes up to 48. Learn when they wear off and manage pain safely.

HOW LONG DOES A PAIN BLOCK LAST AFTER SURGERY? 

WHAT TO EXPECT

WHAT IS A NERVE BLOCKER?

A form of regional anesthesia. Medication is injected near nerves to block pain signals, providing targeted relief during and after surgery.

DURATION: HOURS TO 48 HOURS

Typically 8 - 24 hours; may extend to 48 depending on drug, dose, and site. Effects wear off gradually.

HOW IT WORKS: SODIUM CHANNELS

Local anesthetics block sodium channels in nerve cells, halting impulses and creating numbness with reduced pain.

USED IN: ORTHOPEDICS AND MORE

Common in shoulder, knee, ankle, and soft tissue procedures. Lowers opioid use and supports smoother recovery.

SIGNS IT’S WEARING OFF

Tingling, pins and needles, sensitivity, and gradual pain return are typical. Coordinate scheduled analgesics with your team.

BENEFITS: LESS OPIOIDS, FEWER SIDE EFFECTS

Targeted relief with fewer systemic side effects like nausea or dizziness. Helps earlier mobilization and discharge.

RISKS AND RED FLAGS

Common: Injection site pain/swelling, temporary numbness. Urgent: Severe pain, worsening weakness, infection (redness, fever). Contact your team promptly.

BEYOND THE BLOCK: PAIN PLAN

Transition to oral meds, use ice/heat, resume activity safely, consider physical therapy. Build a personalized plan with your care team.

Stories

More

HEART TEST: POWERFUL DIAGNOSTICS FOR POSITIVE CARDIAC HEALTH

PAIN AFTER NERVE BLOCK: 5 KEY FACTS