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Overview
What Is Pericardial Effusion?
Pericardial effusion is a buildup of extra fluid in the pericardial cavity, the space between the heart and the pericardial sac that surrounds it. A small amount of pericardial fluid normally helps the heart move smoothly. Small or slowly developing effusions may cause few or no symptoms, while a large or rapidly developing collection can put pressure on the heart and impair its function.
Symptoms
Pericardial Effusion Symptoms
Some people with pericardial effusion have no symptoms, especially when the fluid collects slowly. Symptoms may develop when the fluid presses on the heart or lungs and affects circulation or breathing.
- Shortness of breath, especially when lying down.
- Chest discomfort or pressure.
- A rapid heartbeat or pounding heartbeat (palpitations).
- Fatigue or unusual tiredness.
- Lightheadedness or feeling faint.
- Swelling in the legs, ankles, or abdomen.
Causes
Causes of Pericardial Effusion
Pericardial effusion is usually the result of another condition rather than a disease on its own. Inflammation can make the pericardial sac produce extra pericardial fluid, while disease or scarring can interfere with normal fluid drainage. In some cases, the cause is not identified, and a pleuropericardial effusion may involve fluid around both the lungs and heart.
- Pericarditis and autoimmune diseases can inflame the pericardial sac.
- Viral or bacterial infections can cause inflammation and fluid buildup.
- Cancer can spread to or irritate the tissues around the heart.
- Kidney disease or thyroid disease can change fluid balance and contribute to an effusion.
- Heart failure can increase pressure and fluid around the heart.
- Chest injury can damage the pericardial tissues or cause bleeding.
- Heart surgery or other heart procedures can trigger inflammation or fluid accumulation.
- Some medicines or chest radiation can irritate or injure the pericardium.
Risk Factors
Risk Factors for Pericardial Effusion
- A previous episode of pericarditis.
- An autoimmune disease, such as lupus or rheumatoid arthritis.
- A recent or ongoing viral, bacterial, or other infection.
- Cancer or treatment for cancer.
- Kidney disease, particularly when it is advanced or not well controlled.
- Thyroid disease.
- Heart failure or another condition affecting heart function.
- Chest trauma or another injury near the heart.
- Recent cardiac surgery or a heart procedure.
- Previous radiation treatment to the chest.
Most of these are underlying medical conditions, treatments, or injuries rather than personal choices. Some health conditions can be managed, but having a risk factor does not mean that pericardial effusion will develop.
Complications
Complications of Pericardial Effusion
Pericardial Effusion vs. Pericardial Tamponade
An effusion means that fluid has collected around the heart. Pericardial tamponade occurs when pressure from that fluid interferes with the heart’s ability to fill and pump blood. A rapidly increasing effusion can cause low blood pressure, shock, reduced blood flow to vital organs, and life-threatening cardiac tamponade. Other complications include recurrence and problems related to the condition causing the effusion.
Diagnosis
How Pericardial Effusion Is Diagnosed
Clinicians combine symptoms, medical history, a physical examination, and tests to confirm pericardial effusion and assess whether it is affecting heart function. They also look for clues to the underlying cause.
- An echocardiogram uses ultrasound to show fluid around the heart and assess how the heart is filling and pumping.
- An electrocardiogram records the heart’s electrical activity and may show changes related to an effusion.
- A chest X-ray may show an enlarged heart outline or another cause of symptoms.
- CT or MRI scans can provide detailed images of the heart, pericardium, lungs, and nearby tissues.
- Blood tests can look for inflammation, infection, autoimmune disease, thyroid problems, kidney disease, or other causes.
- When drainage is needed, laboratory analysis of pericardial fluid may help identify infection, cancer, blood, or inflammation.
Test results help determine the size and location of the effusion, whether tamponade is present, and what underlying condition may be responsible. An echocardiogram is often especially useful for assessing the effect of fluid on heart function.
Treatment & Management
Pericardial Effusion Treatment and Management
Pericardial effusion treatment is individualized according to the amount and speed of fluid buildup, symptoms, cause, and effect on heart function. A small, stable effusion may be observed with repeat imaging, while the underlying disease is treated when possible.
- Anti-inflammatory or other cause-specific medicines may be used when appropriate.
- Antibiotics may treat selected bacterial infections.
- Cancer treatment or treatment for kidney, thyroid, heart, or autoimmune disease may reduce the effusion.
- Pericardiocentesis uses a needle or catheter to drain fluid, particularly when symptoms or pressure on the heart are present.
- Surgical drainage or a pericardial window may be considered for recurrent, difficult, or cancer-related effusions.
- Emergency treatment is needed when tamponade is impairing circulation.
Follow-up may include reviewing symptoms, physical examinations, and repeat echocardiography when clinicians recommend it. Monitoring helps identify recurrence or changes in heart function and guides ongoing pericardial effusion treatment.
Prevention
Can Pericardial Effusion Be Prevented?
There is no universal way to prevent pericardial effusion, especially when it results from cancer, autoimmune disease, infection, or an unavoidable medical condition. Managing contributing health problems and responding to symptoms early may reduce risk or help detect fluid buildup sooner.
- Work with a healthcare professional to manage heart, kidney, thyroid, and autoimmune conditions.
- Follow the prescribed treatment plan for infections and complete medicines as directed.
- Attend recommended follow-up after heart procedures or chest radiation.
- Seek medical care for new chest discomfort, breathing problems, or other symptoms that could suggest pericardial effusion.
Outlook and Prognosis
Outlook and Prognosis
Many people improve when the underlying cause of pericardial effusion is identified and treated. The outlook varies widely based on the cause, amount of fluid, speed of accumulation, presence of tamponade, overall health, and response to treatment.
An effusion can recur, particularly when the underlying condition remains active or is difficult to treat. Follow-up care helps clinicians watch for returning fluid, worsening symptoms, and changes in heart function without assuming a fixed recovery time.
When Should You See a Doctor
When Should You See a Doctor?
Get urgent help
Possible signs of an emergency
Seek emergency care for severe or sudden shortness of breath, chest pain or pressure, fainting or near-fainting, confusion, bluish lips, marked weakness, or rapidly worsening symptoms. These signs may indicate impaired heart function or cardiac tamponade.
Arrange prompt medical evaluation for persistent breathlessness, new chest discomfort, palpitations, swelling, or fever. Contact a healthcare professional promptly if symptoms occur after a heart procedure, infection, chest injury, or cancer diagnosis, because these situations can be associated with pericardial effusion or pericardial tamponade.
Branches
1 topic
Pericardial Effusion
Cardiology
Symptoms
3 topics
Pericardial Effusion
Chest Pain
Pericardial Effusion
Chest Pain When Breathing
Pericardial Effusion
Palpitations




