Hepatoblastoma is a rare liver cancer in young children. AFP helps diagnose, guide treatment, and detect recurrence.

HEPATOBLASTOMA

RARE LIVER CANCER IN CHILDREN

WHAT IS HEPATOBLASTOMA

Hepatoblastoma is a rare liver cancer found mainly in children under three. It accounts for about 1% of childhood cancers. Early detection is key.

SYMPTOMS TO WATCH

Common signs include swelling in the belly, loss of appetite, weight loss, fatigue, and raised liver markers like AFP.

ROLE OF TUMOR MARKERS

Tumor markers are molecules made by cancer or the body in response. AFP is the main marker for hepatoblastoma, guiding diagnosis and treatment monitoring.

ALPHA-FETOPROTEIN AFP

AFP is a liver protein. High levels in children may indicate hepatoblastoma. Tracking AFP shows how treatments work and detects recurrence early.

MONITORING DURING TREATMENT

AFP tests are done before surgery, after surgery, during chemotherapy, and for follow-ups. Regular checks guide doctors in adjusting treatment.

OTHER TUMOR MARKERS

Researchers also study β-hCG, DCP, and GPC3. These may help when AFP is low or to track tumor aggression.

DIAGNOSIS BEYOND MARKERS

Accurate diagnosis uses imaging (ultrasound, CT, MRI), biopsy, and genetic testing. Tumor markers alone are not enough.

SUPPORT FOR FAMILIES

Families should understand AFP testing, emotional support, and follow-ups. Access resources, counseling, and support groups to cope with hepatoblastoma.

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