GIFT is a specialized fertility procedure where eggs and sperm are placed directly into the fallopian tube to allow natural fertilization. It is one of the available GIFT infertility treatment methods.
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Gamete Intratubal Transfer (GIFT) is a form of Assisted Reproductive Technology (ART) that offers a pathway to pregnancy for specific patients facing infertility. Unlike In Vitro Fertilization (IVF), GIFT allows the crucial step of fertilization to happen naturally inside the woman’s body, specifically within the fallopian tube. This is a significant distinction that makes the procedure appealing to some couples.
The GIFT procedure involves stimulating the woman’s ovaries to produce multiple eggs, retrieving those eggs, and then immediately mixing them with prepared sperm. This mixture of eggs (gametes) and sperm is then quickly transferred into the fallopian tube. The success of this method relies on the fallopian tubes being healthy and functional. GIFT infertility treatment is often chosen by patients who prefer the fertilization process to occur naturally in vivo (inside the body).
Gamete Intratubal Transfer (GIFT) is formally defined as the transfer of eggs (oocytes) and sperm (gametes) into the fallopian tube (intratubal) to achieve fertilization. This contrasts with IVF, where fertilization occurs outside the body.
The word Gamete refers to the reproductive cells, the egg and the sperm. The term Intratubal is derived from Latin, meaning intra (within) and tubal (referring to the fallopian tube). Therefore, the procedure is literally named for its function: transferring reproductive cells into the fallopian tube. The etymology clearly defines the location where fertilization is intended to take place.
Understanding the distinctions between various fertility procedures is critical for choosing the right GIFT infertility treatment plan.
While GIFT is not as widely used as IVF today, it remains an effective option for specific types of infertility, especially when conditions are milder or related to issues outside the fallopian tubes.
The GIFT procedure involves all core components of the female reproductive system, particularly the ovaries, where the gametes originate, and the fallopian tubes, where the transfer occurs.
GIFT holds importance as one of the established Intrafallopian gamete transfer techniques. It provides an option that, for some couples, is seen as more “natural” because fertilization happens within the body. While IVF has largely overtaken its use, GIFT remains a valuable tool for cases of unexplained infertility where the issue is suspected to be a barrier before the fallopian tube.
Furthermore, the development of GIFT paved the way for other in vivo and ex vivo fertility techniques. It confirmed the viability of transferring eggs and sperm directly into the fallopian tube, furthering the evolution of reproductive medicine. The procedure continues to be offered where applicable, ensuring patients have a broad range of GIFT infertility treatment choices.
The successful execution of an Intrafallopian gamete transfer procedure requires the collaborative expertise of multiple specialized medical teams at LIV Hospital.
Send us all your questions or requests, and our expert team will assist you.
The main warning sign is the inability to conceive after 12 months of unprotected intercourse (or 6 months if the female partner is over 35).
Individuals with advanced maternal age (over 35), a history of endometriosis, prior pelvic infections, or poor semen analysis results are considered to be at higher risk.
Yes, women often present with symptoms like irregular periods or pelvic pain, while male infertility is typically diagnosed through semen analysis, often without noticeable symptoms.
Major lifestyle factors include smoking, excessive consumption of alcohol, being significantly overweight or underweight, and high levels of chronic, unmanaged stress.
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