Acne is mainly diagnosed by physical examination. Learn when advanced hormone tests or a skin biopsy are needed, and how dermatologists determine the severity of your condition.

We're Here to Help.
Get in Touch.

Send us all your questions or requests, and our expert team will assist you.

Doctors

Acne: Diagnosis and Evaluation

Dermatology is the branch of medicine and surgery dedicated to the diagnosis, treatment, and prevention of diseases affecting the skin, hair, nails, and mucous membranes. As the skin is the largest and most visible organ of the human body, it serves as the first line of defense against injury and bacteria, as well as a window into the body’s overall health. A Dermatologist is a specialist physician trained to manage over 3,000 different conditions, ranging from cosmetic concerns like wrinkles to life-threatening diseases like melanoma.

Icon LIV Hospital

Common Screening Tests for Acne

DERMATOLOGY

Acne is primarily diagnosed visually by a dermatologist, making the clinical examination the most important tool. There are generally no routine blood tests for acne itself. The specialist uses the physical exam to classify the exact type and severity of the acne present, which is the key information needed to decide on the best course of treatment.

The visual screening process involves:

Severity Assessment: 

The doctor carefully counts and categorizes the blemishes (blackheads, whiteheads, papules, pustules, nodules, or cysts). This allows the dermatologist to grade the acne as mild, moderate, or severe. This grading immediately dictates the strength of the prescription needed.

Blemish Analysis: 

The specialist identifies which type of lesion is most dominant. For instance, if most blemishes are deep, painful cysts, the patient is diagnosed with severe acne and needs aggressive systemic medication (like oral Isotretinoin) to prevent permanent scarring.

Advanced Diagnostic Procedures 

Advanced procedures are sometimes necessary when acne is very severe, when it appears suddenly in adulthood, or when it resists standard, strong treatments. These advanced steps focus on ruling out underlying medical causes, especially hormonal issues.

Icon 1 LIV Hospital

What to Expect During an Acne Test

DERMATOLOGY

Here is a step-by-step breakdown of what you can expect during this assessment:

The Comprehensive Interview (Medical History)

The doctor will spend the most time gathering information, as this is how they identify the cause and type of your acne. Expect questions about:

  • Acne History: When did it start? What parts of your body are affected (face, chest, back)? How long have you tried over-the-counter (OTC) products (like benzoyl peroxide)?
  • Current Medications: They will ask for a list of all your prescription drugs, supplements, and oral contraceptives, as some can trigger acne.
  • Lifestyle and Routine: They will review your entire skincare routine (cleansers, moisturizers, makeup) to check for ingredients that might be clogging your pores (comedogenic products).
  • Hormonal Triggers (Especially for Women): They will ask about your menstrual cycle, if you have irregular periods, or if you have any signs of excess hair growth, which can suggest a hormonal cause like PCOS.

The Physical Examination (Visual Diagnosis)

This is the main diagnostic step. You will be asked to remove your makeup (if applicable) and expose the affected areas.

The dermatologist will closely examine your skin to categorize your acne, which determines the treatment plan:

  • Type of Lesions: Are they non-inflammatory (blackheads, whiteheads), inflammatory (papules, pustules), or severe (nodules, cysts)?
  • Severity: Based on the number and type of lesions, they will grade your acne as mild, moderate, or severe.
  • Damage: They will check for signs of scarring (pitted dents or raised bumps) and post-inflammatory hyperpigmentation (dark spots).
DERMATOLOGY

Laboratory Tests (Only if Necessary)

Routine blood work is not usually needed for a standard acne diagnosis. Tests are only ordered when an underlying cause or complication is suspected:

  • Hormone Blood Tests: Done if hormonal imbalance (e.g., PCOS) is suspected due to irregular periods or severe adult acne.
  • Swab or Culture: Performed for unusual or antibiotic-resistant breakouts to rule out fungal or bacterial infections.
  • Monitoring Tests: Monthly blood tests are required during oral isotretinoin treatment to monitor liver function and lipid levels.

Ultimately, you should expect a detailed conversation and a thorough look at your skin, resulting in a personalized treatment plan.

How to Prepare for an Acne Test

If blood hormone tests are ordered, preparation is required to ensure the results are accurate.

  • Go Makeup-Free: Avoid makeup on acne-affected areas so the dermatologist can accurately assess skin color, redness, and lesions.
  • Fasting: Fast 8–12 hours before blood tests, drinking only water, to ensure accurate lab results.
  • Medication Review: Inform your doctor about all medications, especially birth control, as they can affect hormone levels.

Understanding Your Test Results

The dermatologist uses a combination of the physical assessment and any lab results to fully understand the root cause of the acne and create a personalized treatment plan.

  • Visual Exam Result: This provides the grade of acne (mild, moderate, severe). Understanding this grade is crucial; for example, severe cystic acne requires immediate and strong treatment to prevent irreversible scarring.
  • Hormone Test Result: If high androgen levels are confirmed, the treatment plan will include specific anti-androgen medications (like Spironolactone) or hormonal birth control pills that block the effect of these hormones on the oil glands.

When Do You Need a Skin Biopsy?

A skin biopsy is a very rare advanced test for acne. It is only performed when the dermatologist suspects the blemishes are not actually acne, but a different type of rare skin disease or a reaction that mimics acne.

For Undiagnosed, Complex, or Resistant Rashes

If a rash is atypical, has unclear features, or has not responded to standard treatments, a biopsy is necessary to look at the cellular patterns and guide therapy.

This helps differentiate between complex or overlapping inflammatory diseases, such as:

  • Autoimmune Disorders: Such as Cutaneous Lupus Erythematosus, Dermatomyositis, or Vasculitis.
  • Blistering Disorders: Conditions like Bullous Pemphigoid or Pemphigus.
  • Atypical or Severe Psoriasis/Eczema: When the presentation is unclear or highly unusual.
  • Drug Reactions: To confirm that a severe or widespread rash is a specific type of allergic or inflammatory reaction to a medication.

To Identify Unusual Infections

While many skin infections are diagnosed visually, a biopsy is needed when a deep or unusual infection is suspected, such as:

  • Deep Fungal or Bacterial Infections
  • Atypical Mycobacterial Infections

30 Years of
Excellence

Trusted Worldwide

With patients from across the globe, we bring over three decades of medical

Book a Free Certified Online
Doctor Consultation

Clinics/branches

Was this article helpful?

Was this article helpful?

We're Here to Help.
Get in Touch.

Send us all your questions or requests, and our expert team will assist you.

Doctors

FREQUENTLY ASKED QUESTIONS

What tests are used to diagnose acne?

Acne is mainly diagnosed through a physical examination of the skin. Blood tests are sometimes used to check hormone levels, and a skin biopsy is rarely used to rule out other skin diseases.

Preparation usually involves fasting (not eating) for several hours before the blood is drawn and ensuring the test is scheduled on a specific day of the menstrual cycle, if applicable.

No, the physical exam is not painful. A specialist simply looks closely at your face, chest, or back to classify the type and severity of the blemishes present.

A diagnosis based on a physical exam is highly accurate for acne. When blood tests or biopsies are used, they provide precise information to confirm the hormonal cause or rule out other rare diseases.

You need advanced hormone blood testing if your acne is severe, resists standard treatment, or if you have other signs of hormonal imbalance, such as irregular menstrual periods or excess body hair.

Spine Hospital of Louisiana

Let's Talk About Your Health

BUT WAIT, THERE'S MORE...

Leave your phone number and our medical team will call you back to discuss your healthcare needs and answer all your questions.

Let's Talk About Your Health

Let's Talk About Your Health

Leave your phone number and our medical team will call you back to discuss your healthcare needs and answer all your questions.

Let's Talk About Your Health

How helpful was it?

helpful
helpful
helpful
Your Comparison List (you must select at least 2 packages)