What is Urology?

Urology: Urinary & Reproductive Disease Diagnosis & Treatment

Urology treats urinary tract diseases in all genders and male reproductive issues, covering the kidneys, bladder, prostate, urethra, from infections to complex cancers.

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The Diagnostic Approach

Overactive Bladder

The diagnosis of Overactive Bladder at Liv Hospital is a methodical process of exclusion and characterization. Because OAB is defined by its symptoms, there is no single test that can confirm it in isolation. Instead, the diagnostic pathway is designed to rule out other pathologies that mimic OAB—such as infections, tumors, or stones—and to assess the functional status of the lower urinary tract objectively. This ensures the treatment targets the correct physiological mechanism. The process begins with non-invasive assessments and progresses to more specialized testing if the clinical picture is complex.

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Clinical History and Physical Examination

The foundation of the diagnosis is a comprehensive medical history. The urologist explores the specific nature of the symptoms: the intensity of urgency, the frequency of voiding, the presence of leakage, and the impact on quality of life. Differentiating between “urge incontinence” (leakage preceded by a strong desire to void) and “stress incontinence” (leakage with exertion) is critical, although many patients present with “mixed incontinence.” The history also covers fluid intake habits, medication use, and relevant obstetric, gynecological, or neurological history.

A focused physical examination follows. In women, a pelvic exam assesses for urogenital atrophy (tissue thinning due to estrogen loss) and pelvic organ prolapse, which can mechanically irritate the bladder. In men, a digital rectal examination (DRE) evaluates the prostate size and consistency to rule out obstruction or cancer. A neurological assessment of the perineal area and lower extremities evaluates reflexes and sensation, helping identify potential neurogenic causes, such as spinal cord issues.

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The Bladder Diary

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One of the most valuable diagnostic tools is the Bladder Diary. Patients are asked to maintain a detailed log for a period, typically three days. In this diary, they record:

  • The time and volume of fluid intake.
  • The time and volume of every void (urination).
  • Episodes of urgency and their severity.
  • Episodes of incontinence and the activity associated with them. The bladder diary provides objective data that often differs from patient recall. It helps distinguish between polyuria (producing excessive total urine volume, often due to diabetes or excessive drinking) and frequency (voiding small amounts frequently due to OAB). It reveals functional bladder capacity and helps identify dietary triggers, such as caffeine timing.

Urinalysis and Laboratory Tests

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A urinalysis is mandatory for every patient presenting with OAB symptoms. This simple test screens for:

  • Infection: Bacteria and white blood cells indicate a Urinary Tract Infection (UTI), which causes temporary urgency and frequency.
  • Hematuria: Blood in the urine can be a sign of bladder stones, tumors, or kidney issues.
  • Glucosuria: Sugar in the urine suggests undiagnosed or poorly controlled diabetes, which can cause excessive urination. If the urinalysis is abnormal, a urine culture or urine cytology (checking for cancer cells) may be ordered. Blood tests may also be performed to assess kidney function (creatinine/BUN) if renal impairment is suspected.

Post-Void Residual (PVR) Measurement

This non-invasive test measures the amount of urine left in the bladder immediately after urination. It is typically performed using a portable ultrasound scanner. A significant amount of residual urine suggests that the bladder is not emptying effectively. This could be due to obstruction (like an enlarged prostate) or a weak bladder muscle (detrusor underactivity). Identifying a high PVR is crucial because prescribing common OAB medications, which relax the bladder, could cause complete urinary retention in these patients.

Urodynamic Testing

When the diagnosis remains unclear or when conservative treatments have failed, Urodynamics is the gold standard for functional assessment. This suite of tests evaluates the hydrodynamics of the lower urinary tract.

  • Uroflowmetry: The patient urinates into a specialized funnel that measures the speed and volume of the stream. It screens for obstruction or weak muscles.
  • Cystometry: This is the core test for OAB. A thin catheter with pressure sensors is inserted into the bladder, and another sensor is placed in the rectum or vagina to measure abdominal pressure. The bladder is slowly filled with sterile water. The test monitors how bladder pressure changes as the bladder fills. It aims to detect detrusor overactivity, which appears as involuntary spikes in bladder pressure that coincide with the patient’s sensation of urgency. It determines the bladder’s stability, compliance (elasticity), and sensory threshold.
  • Pressure-Flow Study: This combines cystometry with uroflowmetry to definitively differentiate between bladder outlet obstruction and bladder muscle weakness.

Imaging and Cystoscopy

In specific cases, imaging such as a renal and bladder ultrasound may be performed to detect structural abnormalities, including stones, diverticula, or wall thickening. Cystoscopy, the visual inspection of the bladder interior using a flexible camera, is not routinely used for uncomplicated OAB but is essential if there is blood in the urine, pain, or risk factors for bladder cancer. It rules out intravesical pathology that could be irritating the bladder lining.

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FREQUENTLY ASKED QUESTIONS

What is the purpose of keeping a bladder diary?
A bladder diary provides an objective record of your bathroom habits. Often, our memory of how much we drink or how often we go is inaccurate. The diary reveals patterns—such as drinking too much fluid in the evening or voiding frequently with tiny volumes—that help the doctor diagnose the specific type of bladder dysfunction and tailor lifestyle advice effectively.

Many urinary tract conditions, including mild infections and early-stage bladder cancer, can mimic the symptoms of Overactive Bladder without causing typical pain. A urinalysis is a crucial screening tool to rule out these “mimics.” Treating an infection or identifying blood in the urine early changes the entire treatment plan and ensures severe conditions are not missed.

Urodynamic testing involves the insertion of small catheters, which can be slightly uncomfortable or embarrassing, but it is generally not painful. A local anesthetic gel is used to numb the urethra. The test is vital for understanding the physics of your bladder—how it holds pressure and muscle tone—information that cannot be gained from a simple exam.

The Post-Void Residual (PVR) test checks whether your bladder empties completely. If you retain a large amount of urine after going to the bathroom, it might indicate a blockage or a weak muscle. Knowing this is critical because some OAB medicines relax the bladder; if you are already retaining urine, these medicines could make it impossible for you to urinate.

Cystoscopy does not diagnose OAB itself, as OAB is a problem with how the bladder functions, not necessarily what it looks like. However, cystoscopy is used to rule out other causes of urgency, such as bladder stones, tumors, or interstitial cystitis. It ensures that the lining of the bladder is healthy and that no physical irritants are causing your symptoms.

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