Mustafa Çelik

Mustafa Çelik

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Can You Eat Before A Ct Scan: Dairy Guide
Can You Eat Before A Ct Scan: Dairy Guide 4

Getting ready for a PET scan is more than just showing up on time. You need to think about what you eat before the scan. Dietary restrictions before a PET scan are crucial for getting accurate results. Can you eat before a ct scan or dairy products? Follow our amazing and vital rules for a perfect and fast imaging result today.

Many people ask if they can eat dairy before a PET scan. The answer depends on how dairy affects the scan’s accuracy. Dairy has carbs and sugars that can mess up the scan’s clear images.

Guidelines say to eat a low-carbohydrate, sugar-free diet for at least 24 hours before the scan. This helps avoid image errors. By following these rules, patients can get more accurate scan results. This leads to a better diagnosis and treatment plan.

Key Takeaways

  • Follow a low-carbohydrate, sugar-free diet for at least 24 hours before a PET scan.
  • Dairy products can interfere with PET scan accuracy due to their carbohydrate and sugar content.
  • Careful dietary preparation is crucial for ensuring accurate PET scan results.
  • Patients should consult their healthcare provider for specific dietary instructions before a PET scan.
  • A well-prepared diet helps in achieving a reliable diagnosis and treatment plan.

The Critical Role of PET Scans in Modern Diagnostics

PET scans have changed how we diagnose diseases. They give deep insights into the body. This makes them key in modern medicine, helping doctors diagnose and treat many conditions well.

What is a PET scan and how does it work?

Can You Eat Before A Ct Scan: Dairy Guide
Can You Eat Before A Ct Scan: Dairy Guide 5

A PET scan is a detailed imaging test. It uses a radioactive tracer to see how active the body’s cells are. During the PET CT scan procedure, the tracer goes to areas with lots of activity, like growing tumors. This lets doctors see tumors and other issues clearly.

Common medical conditions diagnosed with PET scans

PET scans help diagnose and manage many health issues. These include:

  • Cancer diagnosis and staging
  • Neurological disorders, such as Alzheimer’s disease
  • Cardiovascular disease assessment

PET scans show how active cells are. This helps doctors plan better treatments and check if they work.

Why preparation protocols matter for accurate results

Getting ready for a pet scan is very important. The right preparation helps get clear and useful scan images. Preparing for a PET scan means following certain rules to make sure the scan is accurate.

Understanding how PET scans function and adhering to preparation guidelines is essential for patients, as it ensures that their scan results provide valuable information for their doctors.

Why Dietary Restrictions Matter for PET Scan Accuracy

The accuracy of PET scan results depends on following dietary restrictions before the scan. Eating certain foods and drinks can change how the body works. This can make the scan images less clear.

How Radioactive Tracers Interact with Metabolism

PET scans use radioactive tracers to see how the body works. These tracers go into cells based on their activity. Foods high in carbs or sugar can change how the tracer is used.

High blood sugar can make it harder for the tracer to reach cells. This is especially true for cancer scans. If the tracer doesn’t work right, the scan might not show what it should.

The Relationship Between Blood Glucose and Image Quality

Blood sugar levels affect how clear PET scan images are. High sugar can make it harder to see tumors. Keeping blood sugar low before a scan is key for good images.

We tell patients to eat carefully before their scan. Avoid foods with lots of carbs and sugar, like many dairy products.

Statistics on Suboptimal Scans Due to Improper Preparation

Many PET scans aren’t as good as they could be because of bad preparation. This can mean more scans, late diagnoses, and higher costs. Eating right before a scan can help avoid these problems.

  • Up to 20% of PET scans might not be good because of bad food choices.
  • Eating low-carb and sugar-free before a scan can help get better images.
  • Telling patients about what to eat is important for good scan results.

Knowing about dietary rules and following them can help make sure PET scans are accurate. This is important for getting the right diagnosis.

Dairy Products: Why They’re Problematic Before PET Scans

Many patients don’t know that dairy can mess with PET scan results. This is because dairy has carbs and sugars. These can change how glucose is used in the body, leading to wrong PET scan results.

Carbohydrate and Sugar Content in Common Dairy Foods

Different dairy products have different carbs and sugars. For example, milk has lactose, a sugar that can raise blood sugar. Yogurt, especially the flavored kind, has a lot of added sugars. Knowing this is key for patients getting ready for a PET scan.

Dairy Product

Carbohydrate Content (g)

Sugar Content (g)

Milk (1 cup)

12

12

Yogurt (6 oz)

30

20

Cheese (1 oz)

1

0.5

How Lactose and Milk Sugars Affect Glucose Metabolism

Lactose in milk breaks down into glucose and galactose. This can raise blood sugar levels. This is important for PET scans that look at glucose use. Eating dairy before a PET scan can make blood sugar go up, which can mess with the scan’s quality.

“The consumption of lactose-containing products can lead to increased glucose levels, which may interfere with the PET scan’s ability to accurately diagnose certain conditions.”Nuclear Medicine Specialist

Scientific Evidence on Dairy’s Impact on Scan Results

Many studies have looked at how dairy affects PET scans. They show that eating dairy before a scan can make images not as good. A study in the Journal of Nuclear Medicine found that eating dairy before a scan made it more likely that patients needed to do the scan again because the first one wasn’t clear enough.

To get good PET scan results, patients should not eat dairy for a while before their scan. Knowing how dairy affects glucose and PET scans helps patients prepare better. This leads to more accurate results.

Specific Dairy Products to Avoid Before Your Scan

Can You Eat Before A Ct Scan: Dairy Guide
Can You Eat Before A Ct Scan: Dairy Guide 6

Knowing which dairy products to avoid before a PET scan is key. Dairy has sugars and carbs that can mess with glucose levels. This can change how the radioactive tracer works in PET scans.

Milk and Milk Alternatives: What’s Allowed and What’s Not

Milk and milk alternatives are common, but their sugar can be a problem before a PET scan. Milk has lactose, which can change blood sugar levels. It’s best to cut down or avoid regular milk before a PET scan.

Milk alternatives like almond, soy, and coconut milk are okay in small amounts if they’re unsweetened. But, always check the labels for added sugars or carbs.

Dairy Product

Allowed/Not Allowed

Reason

Regular Milk

Not Allowed

Contains lactose, affecting glucose metabolism

Unsweetened Almond Milk

Allowed

Low in carbohydrates and sugars

Sweetened Soy Milk

Not Allowed

Contains added sugars

Yogurt, Cheese, and Other Fermented Dairy Concerns

Yogurt and cheese have different sugars than milk. Plain, unflavored yogurt has less lactose than milk because of fermentation. But, flavored yogurts often have added sugars. Cheese, especially hard types, has less lactose but can still affect blood sugar.

“The fermentation process in yogurt and cheese reduces lactose content, but added flavorings and sugars can still affect PET scan results.”—Nuclear Medicine Specialist

Hidden Dairy Ingredients in Processed Foods

Many processed foods have hidden dairy like whey, casein, or lactose. Always check food labels for dairy ingredients.

Some foods with hidden dairy include:

  • Baked goods (cakes, cookies, pastries)
  • Processed meats (sausages, deli meats)
  • Ready-to-eat meals (soups, frozen dinners)

By watching out for these dairy products and hidden ingredients, patients can prepare better for their PET scan. This helps get more accurate and reliable results.

Complete Dietary Guidelines: 24 Hours Before Your PET Scan

The 24 hours before your PET scan are key. Eating a low-carb, sugar-free diet is vital for clear images. This diet ensures your scan gives accurate results.

Low-Carbohydrate, Sugar-Free Preparation Diet

Avoid foods high in sugar and carbs 24 hours before your PET scan. These can mess with the scan’s accuracy. Choose foods high in protein and healthy fats instead. They keep your blood sugar stable and improve scan quality.

Stay away from sugary drinks and baked goods. Also, skip starchy veggies like potatoes and corn. Instead, eat lean meats, fish, and eggs. Always check food labels for hidden sugars and carbs.

Protein-Focused Meal Planning

Protein is key in your pre-PET scan diet. Make sure to include protein in every meal. This helps keep your blood sugar steady and supports your health. Good protein sources are lean meats, fish, eggs, and tofu.

Try to mix up your protein sources to keep your diet interesting. Getting advice from a healthcare pro or dietitian can also help.

Acceptable Non-Starchy Vegetables and Other Foods

Non-starchy veggies are also important in your diet before the PET scan. They’re low in carbs and good for your health. Examples include spinach, kale, broccoli, cauliflower, and bell peppers.

Healthy fats like avocado and olive oil are okay too. So are low-carb condiments and seasonings. But avoid foods high in sugar and carbs, and those with artificial sweeteners.

The Critical 6-Hour Window: Fasting Requirements Explained

Knowing the 6-hour fasting period before a PET scan is key for good results. We tell patients to fast for at least 6 hours before their scan. This ensures the best quality images.

Necessity of Complete Fasting

Complete fasting before a PET scan is needed for accurate results. Eating or drinking anything other than water can change your blood sugar. This can make the scan images not as good.

It’s important to not eat or drink anything except water during fasting. This means no dairy, sugary drinks, or any food that has calories. These can mess up your scan results.

Water Consumption Guidelines

While fasting, drinking water is okay. Staying hydrated is important, but don’t drink too much. We suggest drinking water in small amounts.

Also, avoid caffeinated drinks and anything that might make you uncomfortable during the scan. Drinking too much water can be uncomfortable during the scan.

Emergency Exceptions to Fasting Rules

If you have a medical condition like diabetes, you might need a different plan. It’s important to talk to your healthcare provider about your medical history and any concerns before the scan.

If fasting is not possible due to medical reasons, we can adjust the preparation. We try to get the best scan results possible for you.

Key Points to Remember:

  • Fast for at least 6 hours before your PET scan.
  • Water consumption is allowed during fasting, but in moderation.
  • Discuss any medical conditions or concerns with your healthcare provider.

Can You Eat Before a CT Scan? Comparing Different Imaging Preparations

Dietary preparations for CT scans are different from PET scans. Knowing these differences is important for a successful scan. It’s key to understand if you can eat before a CT scan and how it compares to other imaging techniques.

CT Scan vs. PET Scan Dietary Guidelines

CT scan dietary guidelines are less strict than PET scans. For a CT scan, the rules can change if a contrast agent is used. If no contrast is used, patients can eat and drink normally before the scan.

If a contrast agent is used, patients might need to avoid eating for a few hours. This is to reduce the risk of nausea.

PET scans, however, have stricter dietary rules. Patients need to fast for several hours before the scan. This ensures accurate glucose metabolism readings.

Imaging Type

Dietary Restrictions

Contrast Agent Use

CT Scan without Contrast

No restrictions

No

CT Scan with Contrast

Avoid eating for a few hours

Yes

PET Scan

Fasting required for several hours

Not applicable

Why Requirements Differ Between Imaging Technologies

CT and PET scans have different dietary needs because of their technologies and uses. CT scans use X-rays to create detailed images of the body. They are used to diagnose injuries, cancers, and vascular diseases.

PET scans, however, use a radioactive tracer to see metabolic processes in the body. They are great for diagnosing and monitoring conditions like cancer.

CT Scan with Contrast vs. Without Contrast Preparations

For CT scans with contrast, patients should avoid eating for a few hours before. This reduces the risk of nausea when the contrast agent is given. Drinking water is usually encouraged, but instructions can vary based on the contrast type and patient health.

For CT scans without contrast, there are no dietary restrictions. Patients can eat and drink as they normally would.

Sample Menu Plan for Optimal PET Scan Preparation

Getting ready for a PET scan means planning your meals carefully. We’ll show you a sample menu to help you prepare well. A good meal plan is key in the 24 hours before your scan. This guide will help you choose the right foods for accurate scan results.

24-12 hours before: Low-carb meal options

In the 24 to 12 hours before your PET scan, eat low-carb meals. Try grilled chicken or fish with roasted veggies, salads with chicken or tofu, and vegetable stir-fries with lean meats. These meals keep your blood sugar stable, which is important for a good scan.

Here are some low-carb meal ideas:

  • Grilled salmon with green beans
  • Turkey lettuce wraps with avocado and tomato
  • Cauliflower rice stir-fry with chicken and veggies

12-6 hours before: Final meal suggestions

Between 12 and 6 hours before your PET scan, stick to low-carb, sugar-free meals. Avoid foods that might mess up your scan results. Choose plain, unflavored foods and skip anything with added sugars or carbs.

Here are some meal ideas:

  1. Plain Greek yogurt with a small amount of berries (if okay by your diet)
  2. Scrambled eggs with spinach
  3. Grilled chicken breast with steamed broccoli

Dairy-free alternatives for common meals

If you can’t have dairy, there are alternatives for your meals. For breakfast, try almond milk or coconut milk-based cereals, or dairy-free yogurt made from almond or coconut milk.

Some dairy-free options include:

  • Almond milk or soy milk instead of regular milk
  • Dairy-free cheese for sandwiches or salads
  • Coconut yogurt or cashew-based desserts

Medical experts say, “Following a strict diet before a PET scan is key for accurate results.” Sticking to the recommended diet will make your PET scan more effective.

Special Considerations for Diabetic Patients

Diabetic patients need to think carefully about their medication and blood sugar levels before a PET scan. It’s important to make sure the scan is safe and works well.

Modified Fasting Protocols for Diabetes

Diabetic patients might have to change their fasting plans before a PET scan. It’s crucial to follow the specific instructions provided by your healthcare provider. They might suggest a different fasting plan to keep blood sugar levels right.

For example, people on insulin or some oral meds might need to change their doses or when they take them.

“Managing diabetes before a PET scan is a careful balance,” saysan endocrinologist. “Doctors must think about the type of diabetes, how well blood sugar is controlled, and the patient’s meds when giving advice on PET scan prep.”

Medication Adjustments Before Scanning

Diabetic patients often need to adjust their meds before a PET scan. Some meds, like metformin, might not need changing, but others, like insulin or sulfonylureas, might. It’s essential to talk to your healthcare provider about your meds.

  • Review your current medications with your healthcare provider.
  • Discuss potential adjustments to your medication schedule.
  • Monitor your blood glucose levels closely in the days leading up to the scan.

Blood Glucose Monitoring Requirements

It’s very important to keep a close eye on blood sugar levels before a PET scan. Diabetic patients should check their sugar more often than usual. They should also know the signs of low and high blood sugar. Having a plan for managing these issues is key.

By managing their diabetes well and following their healthcare provider’s advice, diabetic patients can have a safe and effective PET scan.

Medications and Supplements That Can Interfere With PET Scans

Before getting a PET scan, it’s important to know that some medicines and supplements can mess with the scan’s results. Knowing which ones can affect the scan helps get a correct diagnosis.

Prescription Medications to Discuss with Your Doctor

Certain prescription drugs can change how a PET scan works. Tell your doctor about all the medicines you’re taking. This includes diabetes meds, as they can change how the body uses glucose, which is key for PET scans. For example, metformin, a common diabetes drug, can change where the scan’s dye goes, which might affect what the scan shows.

Other drugs that might mess with PET scan results include heart rate and blood pressure meds, and some antidepressants. Your doctor might tell you to stop or change the dose of these drugs before your scan.

Over-the-Counter Products to Avoid

Not just prescription drugs, but some OTC products can also mess with PET scan results. Even OTC meds and supplements can affect your scan. Things like cough syrups, some vitamins, and caffeine can change how glucose is used in the body, which affects the scan images.

Be careful with OTC cough syrups, vitamins, and anything with caffeine or stimulants. Talk to your doctor about any OTC meds or supplements you’re taking to see if you should avoid them before your PET scan.

Timing of Medication Intake Before Scanning

When you take your meds before a PET scan is very important. The timing can really affect the scan’s accuracy. Your doctor will tell you when to take your meds, usually right before the scan. But, this can change based on the type of medication and your health.

Also, follow any fasting or diet rules your healthcare team gives you. By managing your meds and following their advice, you can help make sure your PET scan is accurate and helpful for your diagnosis.

Beyond Diet: Complete PET Scan Preparation Guidelines

A successful PET scan needs careful preparation. This includes more than just what you eat. It also involves staying hydrated, exercising lightly, and keeping clean. A complete preparation plan is key to getting accurate results.

Hydration Recommendations

Drinking enough water is crucial before a PET scan. We recommend drinking plenty of water before your scan. But, always follow your doctor’s specific hydration advice, as it may vary based on your health.

Staying hydrated helps the tracer spread evenly in your body. This can lead to clearer images. Some medical conditions may need special fluid intake. Always talk to your doctor about your hydration plan.

Physical Activity Limitations

While exercise is good, avoid strenuous exercise before your PET scan. Intense workouts can mess with the tracer’s spread. This might affect the scan’s quality.

Light to moderate activities are usually okay. But, check with your doctor about what’s right for you. They can guide you based on your health and the scan’s needs.

Can You Shower Before a PET Scan?

Keeping clean is important before a PET scan. You can usually shower before your scan. Just remember to avoid using lotions, creams, or deodorants. They can interfere with the scan. Also, follow any special hygiene instructions from your healthcare team.

By following these guidelines on hydration, exercise, and hygiene, you help make your PET scan safe and effective. This ensures your healthcare team gets the accurate info they need to care for you.

What Happens During Your PET Scan Procedure

Learning about the PET scan procedure can ease your worries. We’ll walk you through each step, from when you arrive to when the scan is done. This will make your experience as easy as possible.

Arrival and Initial Preparation

When you arrive, our staff will welcome you and explain the first steps. You’ll change into a comfy gown and take off any metal items or jewelry. They’ll also check your medical history and any medicines you’re taking to keep you safe.

Tracer Injection and Uptake Period

A radioactive tracer is injected into your vein. You’ll then wait, usually about 60 minutes, for it to spread through your body. You’ll need to stay still and quiet during this time.

The tracer accumulates in active areas, like growing cancer cells. This helps the PET scan show detailed images of your body’s metabolic processes. It aids doctors in diagnosing and tracking various conditions.

The Scanning Process and Duration

After the tracer spreads, you’ll go into the PET scanner. The scan takes 30 to 60 minutes, depending on the type and area being examined. You’ll lie still on a table that slides into the scanner. The machine will move around you, capturing images from different angles.

Feeling a bit claustrophobic is normal, but our staff is here to help. We use various methods and tools to ease any discomfort or anxiety.

Once the scan is over, you can go back to your usual activities unless your doctor says otherwise. Our team will then analyze the images and send them to your healthcare provider for review.

Consequences of Not Following Dietary Guidelines

Not following dietary guidelines before a PET scan can affect the accuracy of the results. If patients don’t follow the recommended diet, it can lead to poor image quality. This might result in false-negative or unclear findings.

Impact on Image Quality

PET scan images depend on the patient’s metabolic state at the time of the scan. Foods or drinks high in sugar or carbs can change glucose metabolism. This can reduce tracer uptake in tissues, making images less accurate.

A study in the Journal of Nuclear Medicine showed that bad diet can cause many scans to be unclear. The researchers stressed the need for strict diet adherence for clear images.

“Adherence to dietary guidelines is crucial for obtaining accurate PET scan results. Failure to comply can lead to compromised image quality and potentially misleading diagnostic information.”Nuclear Medicine Expert

Potential for False-Negative or Inconclusive Results

False-negative results can be serious, as they miss conditions that are present. If a scan is bad because of diet, it might delay diagnosis or treatment. Inconclusive results can mean more tests, adding to costs and stress.

Consequence

Description

Impact

Suboptimal Image Quality

Reduced tracer uptake due to dietary factors

Potential for misdiagnosis or delayed diagnosis

False-Negative Results

Failure to detect a condition due to compromised scan quality

Delayed or inappropriate treatment

Inconclusive Results

Need for additional testing due to unclear scan findings

Increased financial and emotional burden

Financial and Time Costs of Rescheduling

When a PET scan is bad because of diet, it often needs to be rescheduled. This adds costs and delays diagnosis. The costs include the scan, more tests, and possibly longer hospital stays.

We know how important accurate diagnosis is. Proper PET scan preparation is key. By following dietary guidelines, patients help ensure reliable scan results. This helps in getting timely and right care.

Post-Scan Dietary Recommendations

After your PET scan, it’s important to follow certain dietary guidelines. These help get rid of the radiotracer and aid in your recovery.

Resuming Normal Eating

You can start eating normally after your PET scan. But, start with light meals first. Then, gradually move to your usual diet. This helps your stomach adjust without any issues.

Hydration After the Procedure

Drinking lots of water is key after a PET scan. Drinking plenty of water helps remove the radiotracer. Aim for 8 to 10 glasses of water in 24 hours. This not only helps get rid of the radiotracer but also aids in recovery.

Foods That Help Clear the Radiotracer

There’s no food that can speed up the radiotracer’s clearance. But, eating a balanced diet with antioxidants, fiber, and essential nutrients is good for your health. Foods like fruits, vegetables, whole grains, and lean proteins are beneficial.

  • Fruits such as berries, citrus fruits, and apples are rich in antioxidants.
  • Vegetables like leafy greens, broccoli, and bell peppers are packed with vitamins and minerals.
  • Whole grains including brown rice, quinoa, and whole-wheat bread provide fiber.
  • Lean proteins found in poultry, fish, and legumes support overall bodily functions.

Some foods may help your body detox naturally. For example, foods high in fiber can help with bowel movements. This can aid in getting rid of the radiotracer. But, always talk to your healthcare provider before changing your diet.

Livhospital’s Evidence-Based PET Scan Protocols

At Livhospital, we follow the latest research in PET scan protocols. Our goal is to give top-notch diagnostic services. We prepare carefully and focus on our patients.

Academic Research Supporting Dietary Guidelines

Our PET scan diet plans are based on new studies. These studies show how food affects glucose and image quality. A diet low in carbs and sugar before a scan improves results.

A study in the Journal of Nuclear Medicine supports this. It found a low-carb, sugar-free diet helps avoid bad scan results. Our diet plan is easy to follow and boosts image quality.

Dietary Component

Recommended Intake

Rationale

Carbohydrates

Low

Reduces glucose metabolism interference

Sugars

Avoid

Minimizes insulin-related image distortion

Protein

Moderate to High

Supports stable energy levels

Patient-Centered Preparation Approach

Preparing for a PET scan can be tough. That’s why we focus on our patients. We help them understand what to do and offer support every step of the way.

We give clear instructions and meal plans. Our team is here to answer any questions. We want our patients to get the best images and outcomes.

Quality Assurance Measures for Optimal Imaging

We take quality very seriously in our PET scans. From start to finish, we follow strict rules. This ensures our images are accurate.

We keep our equipment in top shape and train our staff well. We also watch our processes closely. This way, we can give our patients reliable results.

At Livhospital, we’re all about quality and care. We use the latest research and listen to our patients. Our goal is to give the best diagnostic services.

Conclusion: Ensuring Your PET Scan Provides Accurate Diagnostic Information

Getting ready for a PET scan is key to getting good results. At Livhospital, we focus on top-notch patient care and follow the latest research. This way, we make sure our patients get the most accurate info.

By sticking to the diet and prep tips in this article, patients can help get the best scan results. Our team is here to help every step of the way. We support you from prep to scan.

At Livhospital, we know how crucial accurate PET scans are for good care. We use the latest tech and follow the best practices. This helps us give our patients the best diagnostic info. It supports better treatment choices and better health outcomes.

FAQ

Can I eat dairy products before a PET scan?

No, you should avoid dairy for at least 24 hours before a PET scan. Dairy has carbs and sugars that can change how your body uses glucose. This can affect the scan’s results.

What foods should I avoid before a PET scan?

Stay away from foods high in carbs and sugars, like dairy, sugary drinks, and starchy veggies. Eat more protein and non-starchy veggies instead.

How long should I fast before a PET scan?

Fast for at least 6 hours before your PET scan. You can drink water, but no food or other drinks.

Can I drink water before a PET scan?

Yes, you can have water during the 6-hour fast. Drinking water is good, but don’t drink too much right before the scan.

Are there any specific dietary guidelines for diabetic patients undergoing a PET scan?

Yes, diabetics might need special fasting rules and to adjust their meds before a PET scan. Talk to your doctor about managing your blood sugar.

Can I take my medications before a PET scan?

Some meds might mess with PET scan results. Check with your doctor about when to take your meds before the scan.

What happens if I don’t follow the dietary guidelines before a PET scan?

Ignoring dietary rules can harm image quality. This might lead to wrong or unclear results. You might need to reschedule, costing time and money.

When can I resume normal eating after a PET scan?

You can eat normally after the scan is done. Drinking water helps get rid of the radiotracer.

Are there any specific foods that can help clear the radiotracer after a PET scan?

No foods can clear the radiotracer fast. But, staying hydrated and eating well helps your body recover.

Can I shower before a PET scan?

Yes, showering before a PET scan is okay. Being clean helps the scan go smoothly.

Are there any physical activity limitations before a PET scan?

Avoid hard exercise before a PET scan. It can mess with glucose use and scan results. Talk to your doctor about what’s okay.

References

National Center for Biotechnology Information: https://www.ncbi.nlm.nih.gov/books/NBK559089/

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