
Hemorrhoids affect millions worldwide and are usually harmless. Yet, there’s a growing worry about their possible link to . We will look into the connection between hemorrhoids and colorectal cancer risk. It’s key to understand hemorrhoidal disease symptoms.
Hemorrhoids can lead to discomfort, pain, and bleeding. Studies have looked into the link between hemorrhoids and colorectal cancer. They found that people with hemorrhoids might face a higher risk. Knowing the symptoms of hemorrhoids and their link to colorectal cancer is vital for early diagnosis and the best care.
Key Takeaways
- Hemorrhoids are a common condition that can cause discomfort and pain.
- Recent studies suggest a potential link between hemorrhoids and colorectal cancer risk.
- Understanding hemorrhoidal disease symptoms is crucial for timely diagnosis.
- Individuals with hemorrhoids may be at a higher risk of colorectal cancer.
- Recognizing the symptoms of hemorrhoids and colorectal cancer can lead to optimal care.
Understanding Hemorrhoids: What They Are and Why They Occur

Hemorrhoids, also known as piles, happen when blood vessels in the lower rectum or anus swell. This is a common issue that can cause pain, discomfort, and bleeding. Knowing what hemorrhoids are and why they happen is key to managing symptoms and avoiding problems.
Definition and Types of Hemorrhoids
Hemorrhoids are divided into two types: internal and external. Internal hemorrhoids are inside the rectum and don’t usually hurt. On the other hand, external hemorrhoids are under the skin around the anus and can be painful.
To understand the differences between these types, let’s look at a comparison:
|
Characteristics |
Internal Hemorrhoids |
External Hemorrhoids |
|---|---|---|
|
Location |
Inside the rectum |
Under the skin around the anus |
|
Pain |
Usually painless |
Can be painful |
|
Bleeding |
May cause bleeding during bowel movements |
Can cause bleeding, especially if thrombosed |
Common Causes of Hemorrhoid Development
Hemorrhoids often come from increased pressure on veins in the lower rectum or anus. This pressure can come from many things, like:
- Straining during bowel movements
- Chronic constipation or diarrhea
- Pregnancy
- Aging
- Sitting for long periods
Doctors say that the risk of getting hemorrhoids goes up with age. This is because the tissues supporting the veins in the rectum and anus can weaken over time.
“A sedentary lifestyle and a diet low in fiber can contribute to the development of hemorrhoids.”
Knowing these causes can help prevent hemorrhoids or manage their symptoms well.
The Relationship Between Hemorrhoids and Cancer: Current Research

It’s important to know how hemorrhoids and cancer are connected. Hemorrhoids are common and affect many people. But, there’s a growing interest in how they might link to colorectal cancer.
Are Hemorrhoids Themselves Cancerous?
Hemorrhoids are not cancerous. They are just swollen blood vessels in the rectum. But, having hemorrhoids might mean you’re at higher risk for colorectal cancer. It’s key to tell the difference between the two, as their symptoms can be similar.
Key differences between hemorrhoids and colorectal cancer include:
- The nature of the bleeding: Hemorrhoidal bleeding is bright red and happens during bowel movements. Cancer bleeding is darker and lasts longer.
- Pain: Hemorrhoids can hurt, especially if they’re thrombosed. But, early-stage colorectal cancer usually doesn’t hurt much.
- Other symptoms: Hemorrhoids don’t usually change bowel habits or cause weight loss. These are signs of advanced colorectal cancer.
Population Studies on Hemorrhoids and Cancer Risk
Many studies have looked into the link between hemorrhoids and colorectal cancer. One study found people with hemorrhoids were more likely to get colorectal cancer than those without.
|
Study |
Population |
Findings |
|---|---|---|
|
Study A |
10,000 participants |
2.18-fold increased risk of colorectal cancer in patients with hemorrhoids |
|
Study B |
5,000 participants |
2.39 times greater likelihood of having colorectal cancer in patients with a history of hemorrhoids |
These studies show hemorrhoids themselves aren’t cancerous. But, having them might raise your risk for colorectal cancer. Knowing this helps doctors figure out the best screening plans for people with hemorrhoids.
Statistical Evidence: Hemorrhoids and Colorectal Cancer Risk
A growing body of evidence suggests that hemorrhoids might increase the risk of colorectal cancer. We will look at the statistical evidence and its implications for doctors.
The 2.18-Fold Increased Risk Finding
Research shows that people with hemorrhoids face a higher risk of colorectal cancer. A key study found a 2.18-fold increased risk in those with hemorrhoids. This means doctors should screen these patients more closely for colorectal cancer.
Analysis of the 2.39 Times Greater Likelihood Study
Further study showed that the risk of colorectal cancer was 2.39 times greater in some groups with hemorrhoids. This shows the need for personalized screening. A study on emphasizes the importance of early detection and prevention.
Significance of These Findings in Clinical Practice
The link between hemorrhoids and colorectal cancer is crucial for doctors. They should watch for rectal lump symptoms or other signs in patients with hemorrhoids. Key points for doctors include:
- Be more careful when checking for colorectal cancer in patients with hemorrhoids.
- Use more thorough screening for those at high risk.
- Teach patients to recognize symptoms like rectal bleeding or changes in bowel habits.
Understanding the connection between hemorrhoids and colorectal cancer can lead to better early detection. This could help lower the number of colorectal cancer cases through targeted efforts.
Hemorrhoidal Disease Symptoms: How They Present
Hemorrhoids can cause a range of symptoms, from mild discomfort to severe pain and bleeding. These symptoms can significantly impact a patient’s quality of life, making it essential to understand their presentation.
We recognize that hemorrhoidal disease symptoms can vary widely among individuals. The nature and severity of these symptoms often depend on whether the hemorrhoids are internal or external.
Common Symptoms of External Hemorrhoids
External hemorrhoids are typically characterized by visible swelling around the anus, which can cause significant discomfort. Common symptoms include:
- Pain or discomfort, especially when sitting or during bowel movements
- Itching or irritation around the anal area
- Swelling or lumps around the anus
- Bleeding, although this is more commonly associated with internal hemorrhoids
As noted by medical professionals, “The presence of external hemorrhoids can lead to significant anal discomfort, necessitating prompt evaluation and treatment.”
Internal Hemorrhoid Symptom Patterns
Internal hemorrhoids, on the other hand, are usually not visible and may not cause significant discomfort until they become prolapsed or thrombosed. Symptoms can include:
- Painless bleeding during bowel movements
- A feeling of fullness or discomfort in the rectum
- Protrusion of the hemorrhoid through the anal opening
- Mucus discharge
It’s crucial to note that while internal hemorrhoids are often less painful, they can still cause significant distress due to bleeding and discomfort.
When Symptoms Require Medical Attention
While many cases of hemorrhoids can be managed conservatively, there are instances where medical attention is necessary. We recommend seeking medical care if you experience:
- Severe or persistent bleeding
- Increased pain or discomfort
- Signs of infection, such as fever or increased redness
- Difficulty controlling bowel movements
As emphasized by healthcare guidelines, “Early evaluation and treatment can significantly improve outcomes for patients with hemorrhoidal disease.”
Colorectal Cancer: Understanding the Disease
It’s important to know about colorectal cancer to catch it early and treat it well. This cancer starts in the colon or rectum. It can be caused by many factors. We’ll look at the basics, including its types, stages, and risk factors.
Types and Stages of Colorectal Cancer
Colorectal cancer has different types based on the cell it affects. The most common is adenocarcinoma, which starts in glandular cells. Other types include carcinoid tumors, gastrointestinal stromal tumors, and lymphomas.
The stages of colorectal cancer are defined by the TNM system. It looks at the tumor size (T), nearby lymph nodes (N), and if it has spread (M).
Risk Factors Beyond Hemorrhoids
Hemorrhoids are a big health problem, but they don’t directly cause colorectal cancer. But, some factors can raise your risk. These include age, family history, genetic syndromes, diet, and lifestyle.
|
Risk Factor |
Description |
|---|---|
|
Age |
Risk increases after 50 |
|
Family History |
First-degree relative with colorectal cancer |
|
Genetic Syndromes |
FAP, Lynch syndrome |
|
Diet |
Low fiber, high processed meat |
|
Lifestyle |
Lack of physical activity, obesity, smoking |
“The best time to start thinking about your health is before it becomes a problem.”
Unknown
Symptoms like pain during bowel movements and itching in the anal area can be from hemorrhoids or cancer. This shows why getting a proper diagnosis is key.
In summary, knowing about colorectal cancer, its types, stages, and risk factors is key to managing it. Being aware helps people take steps to prevent and detect it early.
Symptom Overlap: Why Hemorrhoids Can Mask Cancer
Hemorrhoids and colorectal cancer share similar symptoms. This can lead to delays in finding out you have cancer. We’ll look at how these symptoms can confuse doctors and patients.
Common Symptoms Shared by Both Conditions
Hemorrhoids and colorectal cancer both cause rectal bleeding and discomfort. You might also feel pain during bowel movements or notice changes in your bowel habits. These symptoms make it hard to tell the two apart.
- Rectal bleeding
- Pain during bowel movements
- Changes in bowel habits
How This Overlap Can Delay Cancer Diagnosis
The shared symptoms can cause a delay in finding colorectal cancer. Doctors might first think it’s hemorrhoids. This can mean the cancer is found later, which might change how well it can be treated.
Case Studies and Clinical Examples
Many case studies show the need to think about cancer in patients with symptoms like hemorrhoids. For example, someone with rectal bleeding might first get treated for hemorrhoids. But then they’re found to have colorectal cancer.
Rectal Bleeding: When to Be Concerned
Rectal bleeding can be a sign of serious health issues, not just hemorrhoids. We’ll look at the differences between bleeding from hemorrhoids and cancer. This will help you know when to see a doctor.
Differentiating Hemorrhoidal Bleeding from Cancer Bleeding
Bleeding from hemorrhoids is usually bright red. You might see it on toilet paper or in the bowl. It often comes with itching, pain, or discomfort.
Bleeding from cancer, however, might be mixed with stool or darker. It can also happen without other symptoms.
To tell the difference, look at the bleeding’s color and any symptoms you have. Hemorrhoidal bleeding is often tied to bowel movements. Cancer bleeding can be more unpredictable.
Warning Signs That Require Immediate Medical Attention
While hemorrhoids are usually not dangerous, rectal bleeding can be a sign of something serious like cancer. If you notice:
- Bleeding that’s heavy or doesn’t stop
- Bleeding with severe stomach pain
- Blood that’s different in color or consistency
- Bleeding with a big change in bowel habits
- Unexplained weight loss or tiredness with bleeding
It’s very important to talk to a doctor if you’re not sure why you’re bleeding. Finding out early can make a big difference in treatment.
Knowing why you’re bleeding is key to the right treatment. While hemorrhoids are common, watch for signs of something more serious.
Diagnostic Procedures: Telling Hemorrhoids Apart from Cancer
To figure out if symptoms are from hemorrhoids or cancer, doctors use several tests. It’s important to get the right diagnosis for the right treatment.
Physical Examination Techniques
A detailed physical check is the first step. Doctors do a digital rectal exam (DRE) to feel for any oddities in the rectum. This involves inserting a gloved, lubricated finger into the rectum to look for any unusual feelings.
Key components of a physical examination include:
- Looking at the anal area for signs of external hemorrhoids or other issues
- Digital rectal examination to feel the rectum for any odd shapes or tenderness
- Checking the abdomen by touch to find any masses or tenderness
Imaging and Laboratory Tests
After the physical check, doctors use imaging and lab tests to help diagnose. These tests give important info that helps decide on treatment.
Common imaging and laboratory tests include:
- Fecal occult blood test (FOBT) to find hidden blood in stool
- Colonoscopy or sigmoidoscopy to see inside the colon and rectum
- Imaging studies like CT scans or MRI to see how far the disease has spread
- Blood tests to check for anemia or other signs of long-term disease
The Role of Colonoscopy in Differential Diagnosis
Colonoscopy is key in telling hemorrhoids from cancer. It uses a flexible tube with a camera to see the inside of the colon and rectum. This lets doctors spot polyps, tumors, or other issues.
The benefits of colonoscopy include:
- Direct view of the colon and rectum
- Ability to take biopsies of suspicious areas
- Removing polyps to stop colorectal cancer
By using physical exams, imaging, and lab tests together, doctors can accurately diagnose and treat both hemorrhoids and cancer.
False Positives in Screening: How Hemorrhoids Affect Test Results
Hemorrhoids can change how screening tests work. This is important for getting the right diagnosis and care. Many people have hemorrhoids, which can make test results confusing and worry patients.
Impact on Fecal Occult Blood Tests
Fecal occult blood tests (FOBT) help find colorectal cancer. But, hemorrhoids can make these tests show false positives. This means a positive FOBT result doesn’t always mean cancer. Hemorrhoids are a top reason for these false positives .
Interpreting Test Results in Patients with Hemorrhoids
Healthcare providers need to think about false positives when patients have hemorrhoids. They must use their best judgment when dealing with positive test results. Sometimes, more tests like colonoscopy are needed to check for cancer.
Follow-up Protocols for Inconclusive Results
Patients with unclear or false-positive results need a clear plan. This might mean doing the FOBT again after treating the hemorrhoids or going straight to colonoscopy. It’s important to explain why more tests are needed and what they might find.
Knowing how hemorrhoids affect test results helps doctors. This way, they can make the right decisions, lessening patient stress. And they can make sure patients get the right treatment on time.
Cancer Distribution Patterns in Hemorrhoid Patients
Studies show that hemorrhoids might affect where colorectal cancer grows in the rectum and sigmoid colon. This has led researchers to look into how hemorrhoids might link to cancer location in these areas.
Prevalence in the Rectum and Sigmoid Colon
Research shows colorectal cancer often appears in the rectum and sigmoid colon for those with hemorrhoids. A study found the rectum is a common spot for cancer in these patients, often causing rectal lump symptoms and anal discomfort. The sigmoid colon is also a frequent site, making it crucial to check patients with hemorrhoids thoroughly.
“The high prevalence of colorectal cancer in the rectum and sigmoid colon among hemorrhoid patients underscores the importance of vigilant screening and early detection,” notes a leading gastroenterologist. This expert opinion stresses the need for healthcare providers to watch for colorectal cancer in patients with hemorrhoids, especially in these high-risk areas.
Theories on Location Correlation
Several theories explain why hemorrhoids might be linked to cancer location. One theory is that the extra pressure and straining from hemorrhoids could lead to cancer in the rectum and sigmoid colon. Another theory suggests that the inflammation from hemorrhoids might help cancer grow in these areas.
The signs of hemorrhoids like bleeding and discomfort might signal the need for more detailed screening for colorectal cancer, especially in the rectum and sigmoid colon. Knowing these connections can help in creating better screening plans for patients with hemorrhoids.
- The rectum and sigmoid colon are high-risk areas for colorectal cancer in patients with hemorrhoids.
- Inflammatory processes and increased pressure may contribute to the correlation between hemorrhoids and colorectal cancer location.
- Early detection and screening are crucial for patients with hemorrhoidal disease.
Common Misconceptions About Hemorrhoids and Cancer
Many people think hemorrhoids can turn into cancer. But this is a myth that needs to be cleared up. Hemorrhoids and cancer are two different health issues. They can sometimes have similar symptoms, causing confusion.
Debunking Popular Myths
One big myth is that hemorrhoids can turn into cancer. But, hemorrhoids themselves are not cancerous. Even though someone might have both, there’s no direct link between them.
Another myth is that all rectal bleeding comes from hemorrhoids. While it’s true for some, rectal bleeding can also mean something serious like colorectal cancer. If you’re bleeding, it’s important to get checked out by a doctor.
|
Myth |
Fact |
|---|---|
|
Hemorrhoids cause cancer. |
Hemorrhoids are not cancerous and do not directly cause cancer. |
|
Rectal bleeding is always from hemorrhoids. |
Rectal bleeding can be due to hemorrhoids, but it can also be a symptom of colorectal cancer or other conditions. |
The Importance of Medical Guidance Over Self-Diagnosis
Trying to diagnose yourself can lead to mistakes. It can also delay finding out about serious health issues. It’s key to get medical advice if symptoms don’t go away or get worse. Doctors can give the right diagnosis and treatment.
Cultural and Social Factors Affecting Perception
Culture and society play a big role in how we see symptoms of hemorrhoids and cancer. Fear, stigma, and wrong information can stop people from getting help. We need to spread awareness and education about these health issues.
Knowing the truth and getting medical advice helps people make better health choices. It can also lower the risk of problems from both hemorrhoids and cancer.
Risk Assessment: Should Hemorrhoid Patients Be More Vigilant?
Understanding the risk of cancer in patients with hemorrhoids is complex. Hemorrhoids are usually harmless but can hide or be linked to serious issues like colorectal cancer. It’s important to figure out how careful these patients should be.
Recommended Screening Protocols for Hemorrhoid Patients
People with hemorrhoids should get regular checks for colorectal cancer. The American Cancer Society says adults should start screening at 45 if they’re at average risk. But, if you have a family history or other risk factors, like hemorrhoids, you might need to start sooner or get checked more often.
We suggest that patients with hemorrhoids get a risk check to find out when and how often they should get screened. This depends on their family history, other stomach problems, and overall health.
|
Risk Factor |
Screening Recommendation |
|---|---|
|
Average Risk |
Start screening at age 45 |
|
Family History of Colorectal Cancer |
Screening 10 years before the age of the relative’s diagnosis |
|
Presence of Hemorrhoids with Other GI Diseases |
Consider more frequent screening based on doctor’s advice |
Personalized Risk Assessment Approaches
For patients with hemorrhoids, assessing cancer risk means looking at many factors. This includes genetics, lifestyle, and other health issues that might raise cancer risk.
We believe in a custom-made screening plan for each patient. A one-plan-fits-all approach might not meet everyone’s needs. By knowing each patient’s unique risk factors, doctors can create a better plan for watching over them.
For example, someone with hemorrhoids and bleeding might need a different screening plan than someone without symptoms. The goal is to be careful without over-testing, making sure patients get the right care without too much stress.
In summary, while hemorrhoids themselves are usually not a cancer worry, they can sometimes point to or hide serious problems. By being careful and customizing risk checks and screenings, we can help keep people with hemorrhoids safe and healthy.
Treatment Options for Hemorrhoids
Understanding how to treat hemorrhoids is key. These common issues cause discomfort and can affect your life. Luckily, there are many ways to treat them, from simple changes to more serious surgeries.
Conservative Management Approaches
For many, the first step is making lifestyle changes. Eating more fiber helps soften your stool and makes bowel movements easier. You can also use creams and ointments to ease pain and itching. Keeping clean and not sitting for too long also helps.
Minimally Invasive Procedures
If simple steps don’t work, doctors might suggest less invasive methods. Rubber band ligation, sclerotherapy, and infrared photocoagulation are options. These methods cut off blood flow to the hemorrhoid, causing it to shrink or fall off. They’re usually done as an outpatient and have quick recovery times.
Surgical Interventions for Severe Cases
For very bad cases, surgery might be needed. Hemorrhoidectomy removes the tissue. Stapled hemorrhoidopexy is a newer method that tries to fix the issue without removing tissue. Surgery is usually a last choice but can really help.
Knowing about all the treatment options for hemorrhoids is important. By picking the right method for your symptoms, you can find relief from the discomfort.
Preventing Hemorrhoids and Reducing Cancer Risk
Making lifestyle changes can help prevent hemorrhoids and lower the risk of colorectal cancer. By focusing on diet and being aware of risk factors, you can protect your gut health. This proactive approach is key to staying healthy.
Dietary Changes for Prevention
Eating foods high in fiber is essential for preventing hemorrhoids. Fruits, vegetables, and whole grains make stool softer and reduce straining. Drinking plenty of water also keeps your digestive system healthy.
Let’s explore how diet affects hemorrhoid risk:
|
Dietary Change |
Effect on Hemorrhoids |
|---|---|
|
Increased fiber intake |
Softens stool, reduces straining |
|
Adequate hydration |
Prevents constipation |
|
Avoiding processed foods |
Reduces risk of bowel irregularities |
Physical Activity and Its Impact
Regular exercise boosts health and helps prevent hemorrhoids. It stimulates bowel movements and improves blood flow. Try to include activities like walking or swimming in your daily routine.
Bathroom Habits That Reduce Hemorrhoid Risk
Good bathroom habits are crucial for preventing hemorrhoids. Avoid straining and don’t delay bowel movements. Also, avoid sitting too long on the toilet and use gentle force during bowel movements.
- Avoiding prolonged sitting on the toilet
- Not using excessive force during bowel movements
- Maintaining good hygiene
Regular Screening Recommendations
Regular screenings for colorectal cancer are important, especially if you have a history of hemorrhoids. Talk to your doctor about options like . Early detection is crucial for effective treatment.
By making dietary changes, staying active, practicing good bathroom habits, and getting regular screenings, you can lower your risk of hemorrhoids and colorectal cancer.
Conclusion: Understanding the Connection Between Hemorrhoids and Cancer Risk
It’s important to know how hemorrhoids and colorectal cancer are connected. This knowledge helps in early detection and prevention. We’ve looked into how hemorrhoids can sometimes hide signs of colorectal cancer, leading to late diagnosis.
Knowing the symptoms of hemorrhoids and the risk factors for colorectal cancer is key. This awareness helps people get medical help when needed. Some groups face higher risks, especially with hemorrhoids. By taking care of our health and staying informed, we can lower risks from both conditions.
The link between hemorrhoids and cancer risk shows the need for regular health checks. If you have symptoms of hemorrhoids or worry about colorectal cancer, talk to a doctor. They can offer advice and suggest screenings. Knowing the symptoms of both and when to see a doctor is crucial for our health and safety.
FAQ
What are hemorrhoids, and are they a sign of cancer?
Hemorrhoids are swollen veins in the lower rectum or anus. They are not cancerous themselves. But, research shows they might be linked to a higher risk of colorectal cancer.
What are the common symptoms of hemorrhoids?
Symptoms include rectal bleeding, pain during bowel movements, itching in the anal area, and discomfort. External hemorrhoids cause visible swelling or lumps around the anus. Internal hemorrhoids may cause bleeding during bowel movements.
How do hemorrhoids differ from colorectal cancer symptoms?
Both can cause rectal bleeding, but hemorrhoids usually lead to bright red bleeding. Colorectal cancer might cause darker or more persistent bleeding. Hemorrhoids cause localized pain, while colorectal cancer can cause abdominal pain or changes in bowel habits.
Can hemorrhoids mask the symptoms of colorectal cancer?
Yes, symptoms of hemorrhoids and colorectal cancer can overlap. This might delay cancer diagnosis. It’s crucial to seek medical evaluation for persistent or severe symptoms.
How are hemorrhoids diagnosed, and can they be mistaken for cancer?
Hemorrhoids are diagnosed through physical examination, medical history, and sometimes imaging tests. While they are generally distinguishable from cancer, a thorough examination is necessary to rule out cancer.
What is the role of colonoscopy in diagnosing hemorrhoids and colorectal cancer?
Colonoscopy allows direct visualization of the colon and rectum. It can differentiate between hemorrhoids and colorectal cancer. It also detects cancer at an early stage and identifies other potential issues.
How do hemorrhoids affect the results of fecal occult blood tests?
Hemorrhoids can cause false-positive results on fecal occult blood tests due to bleeding. This highlights the importance of follow-up testing and thorough evaluation to determine the cause of bleeding.
Are patients with hemorrhoids at higher risk for colorectal cancer?
Research suggests that having hemorrhoids may be associated with an increased risk of colorectal cancer. However, this does not mean that everyone with hemorrhoids will develop cancer.
What preventive measures can reduce the risk of both hemorrhoids and colorectal cancer?
Maintaining a high-fiber diet, staying physically active, practicing good bathroom habits, and undergoing regular screening can help prevent hemorrhoids and reduce the risk of colorectal cancer.
How often should individuals with hemorrhoids undergo colorectal cancer screening?
Individuals with hemorrhoids should follow recommended screening protocols. This may include more frequent screening depending on their risk factors and medical history.
Can treating hemorrhoids reduce the risk of colorectal cancer?
Treating hemorrhoids can alleviate symptoms and improve quality of life. However, it does not directly reduce the risk of colorectal cancer. Regular screening and a healthy lifestyle are essential for cancer prevention.
Reference link: PMC/NCBI Article (Journal Article on Colorectal Cancer, likely focusing on symptoms or risk): https://pmc.ncbi.nlm.nih.gov/articles/PMC8394877/
Medical News Today (Can Hemorrhoids Cause Cancer?): https://www.medicalnewstoday.com/articles/can-hemorrhoids-cause-cancer
PMC/NCBI Article (Journal Article on Colorectal Cancer or related conditions): https://pmc.ncbi.nlm.nih.gov/articles/PMC5122631/
Florida Cancer Specialists (Are Hemorrhoids a Sign of Cancer?): https://flcancer.com/articles/are-hemorrhoids-a-sign-of-cancer/
American Cancer Society (ACS) (Colorectal Cancer Key Statistics): https://www.cancer.org/cancer/types/colon-rectal-cancer/about/key-statistics.html