
Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that mainly affects the spine and sacroiliac joints. But, new research shows it also has big effects on the heart. People with AS might be up to 60% more likely to get heart disease. Often, heart problems start without any clear signs.
At Liv Hospital, we know how important it is to tackle heart risks linked to AS. We use a team approach that combines rheumatology and advanced heart screening. This helps us find and treat heart disease early on.
It’s key to understand how AS impacts heart health. We look into how AS affects the heart, including the higher risk of heart disease and complications. Our goal is to give our patients the best care possible.
Key Takeaways
- Increased risk of heart disease in patients with ankylosing spondylitis.
- Cardiac complications can develop silently before symptoms emerge.
- Integrated care combining rheumatology and cardiology is essential.
- Early detection and management of heart disease are critical.
- Liv Hospital offers complete care for AS patients with heart risks.
Understanding Ankylosing Spondylitis and Heart Complications

Ankylosing spondylitis (AS) is a chronic disease that affects the spine and heart health. It causes inflammation in the spine, sacroiliac joints, and other areas. This leads to pain and stiffness.
What is Ankylosing Spondylitis?
Ankylosing spondylitis is a type of arthritis that mainly affects the spine. It can also affect other joints. The inflammation in the spinal joints can cause severe pain and discomfort.
In some cases, this inflammation can cause new bone to form on the spine. This can make the vertebrae fuse together. This fusion can lead to a loss of spinal mobility and flexibility.
Prevalence of Cardiac Manifestations
Cardiac problems occur in about 2-10 percent of AS patients. These include aortitis, aortic valve disease, and heart rhythm issues. Research from 2019 shows that AS patients are 1.44 times more likely to have a heart attack and 1.37 times more likely to have a stroke. Sometimes, heart problems start before AS is diagnosed.
The increased risk of heart problems in AS patients highlights the need for close monitoring of heart health.
Age-Related Risk Factors
The risk of heart problems in AS patients can increase with age. As people with AS get older, the effects of chronic inflammation and other risk factors can grow. Regular monitoring and management of cardiovascular risk factors are key to reducing this risk. This includes controlling blood pressure, managing cholesterol levels, and avoiding smoking.
Understanding the connection between AS and heart health is vital for effective care. By recognizing cardiac complications and addressing age-related risks, healthcare providers can help reduce the impact of AS on patients’ lives.
The Impact of Ankylosing Spondylitis and Heart Disease

It’s important to know how ankylosing spondylitis (AS) affects the heart. This is key for keeping the heart healthy. AS’s inflammation can harm the aorta and heart, causing heart problems.
Inflammation and Cardiac Damage
AS’s inflammation can make heart disease worse. Chronic inflammation is a big problem in AS. It plays a big role in heart damage.
We’ll look at how inflammation hurts the heart. We’ll also talk about ways to lessen these effects.
Aortitis and Aortic Valve Disease
Aortitis, or inflammation of the aorta, is a big problem in AS. It can cause aortic valve disease. This includes aortic regurgitation, where blood leaks back into the heart.
- Aortitis can cause fibrosis and dilation of the aortic root.
- Aortic valve disease may result in significant morbidity if not properly managed.
- Regular monitoring is essential for early detection and treatment.
Conduction Abnormalities and Heart Rhythm Disorders
AS can mess with the heart’s electrical system. This leads to conduction abnormalities and heart rhythm disorders. These can be mild or severe and might need medical help.
| Conduction Abnormality | Description | Potential Impact |
| AV Block | Delay or blockage of electrical signals between the atria and ventricles. | Can lead to bradycardia or heart failure if severe. |
| Bundle Branch Block | Delay or blockage of electrical signals along the bundle branches. | May indicate underlying cardiac disease. |
Cardiomyopathy Development
Cardiomyopathy, or heart muscle disease, is another AS complication. The chronic inflammation from AS can cause cardiomyopathy. This makes it hard for the heart to pump blood.
We need to think about the genetic link between AS and heart failure. We also need to consider how hypertension and ischemic stroke affect the heart.
Conclusion: Managing Cardiac Health with Ankylosing Spondylitis
Managing heart health is key for those with ankylosing spondylitis (AS). We’ve talked about how AS can harm the heart. This includes inflammation, damage, and problems with heart rhythm and structure.
To manage AS and heart health, a full plan is needed. This includes controlling diabetes, blood pressure, and cholesterol. A healthy lifestyle is also important, like not smoking, staying at a good weight, and exercising often. Using TNF inhibitors can also help.
Knowing the heart disease risk with AS helps people take care of their hearts. Early detection and treatment of heart problems are vital. This way, the risks of AS on the heart can be lessened. Taking care of the heart is a big part of treating AS.
FAQ
What is the relationship between ankylosing spondylitis and heart disease?
Ankylosing spondylitis (AS) is linked to an increased risk of cardiovascular disease due to chronic systemic inflammation, which can accelerate atherosclerosis and affect heart structures.
How does inflammation in AS affect the heart?
Chronic inflammation in AS can damage blood vessels and heart tissues, leading to fibrosis, valve thickening, conduction abnormalities, and a higher risk of atherosclerotic heart disease.
What are the cardiac manifestations associated with AS?
Common cardiac issues include aortic root dilation, aortic regurgitation, conduction abnormalities like heart block, and rarely, cardiomyopathy or ischemic heart disease.
Can AS cause chest pain or tightness?
Yes, AS-related inflammation of the aorta or heart valves can cause chest pain or tightness, which should be evaluated promptly as it may signal cardiac involvement.
How does age affect the risk of cardiac complications in AS patients?
Older AS patients have a higher risk of cardiovascular complications due to cumulative inflammation, age-related vascular changes, and longer disease duration.
What are the symptoms of heart problems in AS patients?
Symptoms can include chest pain, shortness of breath, palpitations, fatigue, dizziness, or swelling in the legs, depending on the type of cardiac involvement.
How can AS patients manage their cardiac health?
Management includes controlling systemic inflammation with medications, regular cardiovascular check-ups, maintaining a heart-healthy lifestyle, and monitoring for hypertension or lipid abnormalities.
Are there any specific heart conditions that AS patients are at risk for?
AS patients are particularly at risk for aortic regurgitation, conduction abnormalities, and accelerated coronary artery disease.
Can cervical spondylosis affect the heart?
Cervical spondylosis itself does not directly affect the heart, though severe cases can rarely influence autonomic nerve function, but it is generally not considered a cardiac risk factor.
What is the role of a rheumatologist in managing cardiac health in AS patients?
Rheumatologists monitor systemic inflammation, adjust medications to reduce cardiovascular risk, coordinate with cardiologists, and guide lifestyle modifications to protect heart health.
References
National Center for Biotechnology Information. Evidence-Based Medical Insight. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC10497445/