Last Updated on November 24, 2025 by
Severe congenital anomalies happen during fetal development. They often cause serious health problems. These issues can lead to high death rates in newborns and lifelong disabilities.

At Liv Hospital, we focus on top-notch healthcare for these conditions. We use the newest medical tools and methods to help our patients. Our goal is to give complete care that meets the complex needs of those born with severe defects. We combine medical skill with kindness and understanding.
Congenital defects are a big health problem worldwide, affecting millions of babies. These defects happen during pregnancy and can be structural or functional. It’s important to know how common they are and their impact to help improve healthcare.

Congenital heart defects are very common, with about 12.3 per 1,000 births in North America. Around the world, these defects cause about 240,000 newborn deaths in the first 28 days each year. Congenital heart defects are among the most common and severe, with many cases reported globally.
We at our institution are committed to advanced medical care for those with these conditions. We aim to improve the lives of those born with congenital defects.
The death rates for congenital defects are high, with many newborns dying in the first 28 days. Survivors often face chronic health issues, developmental delays, and need ongoing medical care.
We aim to lower these death rates and lessen the long-term effects. We do this through early detection, advanced treatments, and support services. By understanding the global impact of congenital defects, we can improve healthcare for those affected worldwide.
Understanding severe congenital heart defects is key to helping families. These defects are very serious and need quick, expert care.
At our institution, we face the challenges of severe congenital heart defects head-on. Conditions like hypoplastic left heart syndrome and transposition of the great arteries are very serious. They need early diagnosis and treatment.
Hypoplastic left heart syndrome (HLHS) is a serious heart defect. The left side of the heart is not fully developed. It often requires surgery or a heart transplant.
Our team is dedicated to giving top-notch care to babies with HLHS. We use the newest in cardiac surgery and treatment. We aim to support families every step of the way.
Transposition of the great arteries (TGA) is another serious heart defect. The main arteries that carry blood out of the heart are reversed. It needs quick treatment to avoid serious health issues.
We use the latest tools and strategies to treat TGA. Our team works with families to create a care plan. We focus on the best outcomes for each child.
Congenital heart defects are a big cause of infant deaths. In the U.S., they caused 23% of infant deaths from birth defects in 2021. This shows how important research and better treatments are.
We at our institution are committed to studying congenital heart defects. We aim to improve care and outcomes. By using the latest medical knowledge, we can help children and families a lot.
Neural tube defects are severe congenital anomalies. They affect the brain and spine development. These defects happen early in pregnancy and can greatly impact a person’s life.
At Liv Hospital, we focus on caring for those with neural tube defects. Our team uses the latest medical techniques. We aim to meet each patient’s unique needs.
Anencephaly is a severe neural tube defect. It means a major part of the brain, skull, and scalp is missing. This condition is often found before birth and can be very serious.
Key aspects of anencephaly include:
Spina bifida is a neural tube defect that affects the spine. Severe cases can cause serious neurological problems. They need immediate medical care.
Our approach to treating severe spina bifida involves:
Encephalocele is a rare neural tube defect. It involves brain tissue herniating through a skull defect. Other neural defects also exist, each with its own challenges and treatment plans.
We are dedicated to providing caring and detailed care for those with these conditions. We work closely with families to meet their specific needs and situations.
It’s key to understand fatal chromosomal abnormalities for the right medical care. These genetic issues can be very serious and limit life. They need careful management and support.
At Liv Hospital, we focus on giving full care to those with these conditions. Our team works with families to meet their needs. We use the newest medical methods and treatments.
Trisomy 13, or Patau Syndrome, causes severe brain and body problems. People with it often don’t live past their first year.
This condition is caused by an extra chromosome 13. This extra genetic material leads to the serious health issues seen in Patau Syndrome.
Trisomy 18, or Edwards Syndrome, is another serious condition. It causes big delays in development and serious health problems. Most with Trisomy 18 don’t make it past infancy.
Trisomy 18 is identified by an extra chromosome 18. It brings big health challenges, needing detailed medical care.
Other chromosomal issues can be fatal. These highlight the need for genetic counseling and prenatal tests. They help manage risks and conditions well.
At Liv Hospital, we aim to give top-notch healthcare. We offer full support and guidance to patients and families. Our team is here to help those affected by these conditions, providing the care and kindness they need.
Congenital structural malformations are serious conditions that can affect an infant’s survival and health. These malformations are present at birth and can involve different parts of the body. At Liv Hospital, we focus on providing top-notch care for these complex conditions. We use the latest in surgical techniques and treatment.
A congenital diaphragmatic hernia is a birth defect where there’s a hole in the diaphragm. This hole lets organs from the abdomen move into the chest. This can press on the lungs and affect their growth. We offer detailed care for infants with this condition, including surgery and post-operative care.
Key aspects of our treatment for congenital diaphragmatic hernia include:
Severe gastrointestinal defects, like esophageal or intestinal atresia, need quick medical help. These defects can mess up the digestive system and might need surgery. Our team is skilled in handling these complex cases, providing both surgery and support.
Some of the gastrointestinal defects we treat include:
Renal agenesis is when one or both kidneys don’t develop in the fetus. When both kidneys are missing, it’s linked to the Potter sequence. This condition has physical abnormalities due to kidney failure and less amniotic fluid. We offer detailed care and support for families with these diagnoses, including counseling and managing complications.
Our approach includes:
Severe congenital anomalies need detailed and specialized medical care. At Liv Hospital, we aim to offer top-notch healthcare for these issues. We use the newest medical advancements and treatment methods.
Congenital anomalies are defects that happen during fetal development. Our team is here to provide caring and supportive care. We work closely with families to meet their specific needs.
We keep improving how we detect and treat congenital anomalies. Our goal is to give exceptional care and better results for those affected. Our commitment to using the latest academic protocols ensures our patients get the best treatment for complex malformations.
Congenital anomalies are problems that happen during a baby’s growth in the womb. They can cause serious health issues.
The worst congenital defects include heart problems, brain and spine issues, and genetic problems. Also, severe birth defects like diaphragmatic hernia and major gut problems are very serious.
Heart defects at birth are very common. About 12.3 per 1,000 babies in North America are born with them.
Hypoplastic left heart syndrome is a serious heart defect. The left side of the heart is not fully developed. It needs quick and special medical care.
Neural tube defects affect the brain and spine. They include anencephaly and severe spina bifida. These are types of congenital anomalies.
Trisomy 13 and trisomy 18 are genetic problems. They can cause severe and life-threatening issues.
Congenital diaphragmatic hernia is a serious problem. It’s when there’s a hole in the diaphragm. This lets organs move into the chest.
Congenital anomalies can be very harmful to newborns. They can cause a lot of sickness and death. About 240,000 newborns die in the first 28 days every year worldwide.
Liv Hospital offers top-notch care for congenital anomalies. We use the latest medical technology and treatments. We also provide support and guidance every step of the way.
Rissmann, A., et al. (2023). Causes of death in children with congenital anomalies up to 10 years of age: a multi-registry cohort study. BMJ Paediatrics Open, 7(1), e001617. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10367017/
World Health Organization (WHO). (2023, February 26). Congenital disorders. WHO. https://www.who.int/news-room/fact-sheets/detail/birth-defects
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