Cellular rejuvenation is the process through which aged or damaged cells regain their function, returning to a more youthful and healthy state. The goal is to reverse cellular aging, restoring cells' vitality and functionality. Recent advances highlight the importance of stem cells derived from newborn umbilical cord tissue as a significant scientific breakthrough. Exosomes, crucial for tissue repair, have shown impressive results in slowing the aging process and supporting cell renewal.
What is Cellular Rejuvenation?
Cellular rejuvenation is the process of restoring aged or damaged cells so they function as if they were young and healthy. The primary goal is to reverse cellular aging and revive cells' natural abilities. Over time, our cells lose their capacity to divide, become damaged, and are less able to perform essential functions”effects we recognize as signs of aging. Cellular rejuvenation uses targeted interventions to reverse these processes, transforming or renewing old or impaired cells into ones that are youthful, healthy, and functional again.
The Cellular Rejuvenation Process
Cellular rejuvenation relies on several key mechanisms, including telomere elongation, DNA repair and renewal, epigenetic modifications, stimulation of mitosis and cell division, maintenance of proteostasis, and mitophagy. Extending telomeres enables cells to divide more frequently, while DNA repair and renewal maintain the integrity of genetic material. Epigenetic modifications reverse age-related shifts in gene expression, and stimulating mitosis and cell division helps generate youthful, functional cells. Proteostasis keeps cellular proteins working properly, and mitophagy removes and renews damaged cell components, all of which enhance overall cell health and function.
Strong Anti-Aging Effect
Questions such as "Will aging ever stop?, "What is the secret to a long and healthy life?, and "Can we remain forever young? are increasingly common. People everywhere, regardless of gender, are eager to pause the aging process and preserve a youthful, healthy body, mind, and spirit. However, as we get older, the signs of aging become apparent both physically and mentally, and the body's ability to repair tissue slows down. For the past 20 years, exosomes derived from cellular therapies have demonstrated powerful anti-aging effects. Used in treatments ranging from skin rejuvenation and wound healing to spinal cord injury, exosomes are now seen as a promising key to youthfulness.
What is Cellular Aging?
Most diseases do not develop overnight; instead, cellular degradation happens gradually over months or even years, often without immediately impairing the affected organ's function. To help prevent future illnesses, it's important to maintain cellular health by following a healthy lifestyle, consuming proper nutrition, and considering appropriate supplements.
- The World Health Organization categorizes ages as follows: 45-59 years as middle age, 60-74 years as elderly, 75-89 years as senility, and 90 years and older as advanced old age. Biological aging happens as gradual damage builds up in cells and tissues throughout the body.
- Unlike chronological age”which is simply your age in years”biological aging depends on factors beyond your birthdate. Cellular aging involves DNA damage, telomere shortening, and cellular stress. Stem cell renewal naturally helps maintain youthfulness by replacing old or damaged cells with new, healthy ones. This ongoing renewal process keeps the body vibrant and youthful, slows aging, and supports overall health..
What Do Exosomes Do in the Body?
Exosomes are natural vesicles, measuring 50-200 nanometers, that are released by cells into the surrounding environment. They serve as a critical communication network within the body, facilitating the exchange of signals and materials between cells. Exosomes play key roles in transporting substances, activating the immune system, and, most importantly, promoting the healing of damaged tissues.
Effects on Skin Rejuvenation
Exosomes are used to treat age-related skin concerns such as wrinkles, pigmentation, and dullness. Once applied, they activate in targeted areas to stimulate collagen and elastin production and repair the skin's damaged protein structures. Exosomes display strong anti-aging properties, helping to rejuvenate tissue, strengthen the skin, restore lost elasticity and firmness, and support cellular regeneration to recover features lost with aging.
How Are Exosomes Produced?
The production of exosomes is a complex and sensitive process requiring specialized laboratory conditions. Mesenchymal stem cells from the umbilical cord are cultured in cGMP (current Good Manufacturing Practices) laboratories. Once the cells reach a sufficient number, they are subjected to stress through various methods to produce exosomes. The resulting exosomes undergo purification processes to become the final product and are stored as a sterile suspension in a cold chain.
The effects and immune responses should be monitored individually and applied only in reputable centers. Exosomes produced in LivMedCell Regenerative Medicine Stem Cell Center's cGMP-approved laboratories are tested through 10 different quality and characterization tests before application.
Areas of Application
- Acute Lung Injury
- Skin Rejuvenation
- Pigmentation Disorders
- Graft-versus-Host Disease (GvHD)
- Hair Loss
- Spinal Cord Injury
- Duchenne Muscular Dystrophy
- Immune Modulation (T and B Cell Regulation)
- Wound Healing
- Photoaging
- Atopic Dermatitis (AD)
- Osteoarthritis (OA)
Advantages of the Treatment
- Exosomes target specific cells using specialized signaling and biomolecules.
- Their fine membrane enables easy transport to various tissues and organs.
- They accelerate tissue repair and promote faster healing.
- Due to their small size (50 to 200 nanometers), exosomes can easily cross the blood-brain barrier.
Cellular Rejuvenation Program at Liv Hospital
The "HEALTHY REJUVENATION Longevity Program at Liv Hospital is designed to promote physical, mental, and emotional vitality. Its goal is to slow the aging process, enhance quality of life, and extend lifespan. To help prevent disease, the program offers personalized therapies based on comprehensive blood tests, tailoring replenishment treatments to each patient's individual needs.
Cellular Rejuvenation Package
- Comprehensive health check-up
- Exosome therapy
- 1“3 intravenous sessions (administered every 5 days over a 15-day period)
- Manual therapy treatments
- Customized dietary programs
- Accommodation in Istanbul, including a Bosphorus tour and a visit to the Basilica Cistern
* Liv Hospital Editorial Board has contributed to the publication of this content .
* Contents of this page is for informational purposes only. Please consult your doctor for diagnosis and treatment. The content of this page does not include information on medicinal health care at Liv Hospital .
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Frequently Asked Questions
Individuals interested in cellular rejuvenation treatments frequently have questions about what to expect during the procedure and its outcomes.
Lifestyle Changes for Cellular Rejuvenation
In addition to medical treatments, adopting healthy lifestyle habits can significantly support cellular rejuvenation. Making positive changes can help your cells remain youthful and healthy for longer. Consider these lifestyle strategies to promote cellular health:
- Balanced and Nutritious Diet: Eating plenty of fresh fruits, vegetables, whole grains, healthy fats (such as olive oil and avocado), and lean protein sources (like fish and legumes) provides essential antioxidants, vitamins, and minerals to reduce cellular damage and support rejuvenation.
- Regular Exercise: Engaging in cardio, strength training, and stretching improves cell health, boosts metabolism, and helps slow the aging process.
- Adequate Sleep: Getting 7“9 hours of quality sleep each night is vital for cellular repair and renewal.
- Stress Management: Practices such as meditation, deep breathing, yoga, or other relaxation techniques can lower stress levels and help prevent accelerated cellular aging.
- Avoid Smoking and Excessive Alcohol: Limiting or eliminating smoking and heavy alcohol use reduces cellular damage and supports healthy aging.
- Adequate Water Intake: Aim to drink about 8 glasses of water daily to maintain cell health and help the body eliminate toxins.
- Mental and Social Activity: Keeping your mind engaged with activities like puzzles, learning new skills, and maintaining social connections can enhance brain health and slow cognitive aging.
- Health Check-ups and Preventive Care: Regular medical check-ups and early screening are important for overall health and promote cellular rejuvenation.