
Colonoscopy is a key tool in stopping rectal cancer. With colorectal cancer on the rise, the American Cancer Society predicts 154,270 new cases and 52,900 deaths in 2025 in the U.S. It’s clear that we need effective screening methods.
Screening helps find colorectal cancers early, when they’re easier to treat. The American Cancer Society notes a drop in colon or rectal cancer diagnoses. This is mainly due to more screenings and lifestyle changes. For more stats, check out the on colorectal cancer.
Key Takeaways
- Colonoscopy can detect and remove harmful polyps, reducing the risk of colorectal cancer.
- The American Cancer Society estimates 154,270 new cases of colon and rectal cancer in 2025.
- Early detection through screening significantly improves treatment outcomes.
- Lifestyle changes and screening are key factors in reducing colorectal cancer incidence.
- Colorectal cancer is a leading cause of cancer death, stressing the need for prevention.
The Growing Threat of Colorectal Cancer in America

Colorectal cancer is a big problem in the U.S. The numbers are scary and show we need to know more and screen more.
2025 Projections: 154,270 New Cases and 52,900 Deaths
Experts predict a lot of lives will be lost to colorectal cancer in 2025. The American Cancer Society says there will be 154,270 new cases. Sadly, 52,900 people will die from it. These numbers show how serious colorectal cancer is.
Why Colorectal Cancer Remains the Second Leading Cause of Cancer Death
Even with new tech and screening, colorectal cancer is the second biggest killer. Many cases are found too late. Early detection is key to saving lives.
It is essential to emphasize the importance of colon cancer screening. Knowing the risks and acting early can help prevent this disease.
What Exactly Is a Colonoscopy?

A colonoscopy is a medical test that lets doctors see inside the colon and rectum. It’s key for finding and removing polyps that could turn into cancer. This helps prevent colorectal cancer.
The Step-by-Step Procedure Explained
The test starts with sedation to relax the patient. The patient lies on their side. Then, a flexible tube with a camera and light, called a colonoscope, is inserted into the rectum.
The colonoscope moves through the colon, showing the doctor what’s inside on a monitor. Air is added to the colon to make it easier to see.
Equipment and Technology Used During Examination
Today’s colonoscopy tools have high-definition cameras and new imaging tech. This includes narrow-band imaging to see the colon’s lining better.
The colonoscope also has a channel for biopsies or removing polyps during the test.
What Doctors Look For During a Colonoscopy
Doctors check for polyps, inflammation, or bleeding in the colon and rectum. They also search for cancer signs like tumors or ulcers.
|
Finding |
Description |
Action |
|---|---|---|
|
Polyp |
A growth on the inner lining of the colon or rectum |
Removal during colonoscopy or biopsy |
|
Inflammation |
Redness or swelling of the colon or rectum |
Biopsy or further testing |
|
Bleeding |
Blood in the colon or rectum |
Cautionary measures or treatment |
Knowing what a colonoscopy is helps patients prepare. It shows how important it is for their gut health.
How Colonoscopies Prevent Rectal Cancer
Colonoscopies help find and remove polyps that could turn into cancer. This is key in catching and treating cancer early. It’s a big step in stopping cancer before it starts.
The Polyp-to-Cancer Pathway
Most colorectal cancers start from polyps in the colon or rectum. These polyps can grow into cancer over years. Colonoscopies let doctors take out these polyps before they become cancer.
By removing these polyps, colonoscopies stop cancer from forming. This is a major reason why screenings are so important.
Early Detection and Removal of Precancerous Growths
Finding cancer early is key to stopping it. Colonoscopies let doctors see inside the colon and rectum. They can spot and remove polyps that might turn into cancer.
Colonoscopies do more than just prevent cancer. They also help find other problems in the gut, like diverticulosis and inflammatory bowel disease.
Scientific Evidence of Cancer Prevention Through Screening
Many studies show colonoscopies really work in stopping colorectal cancer. By taking out polyps early, they greatly lower the risk of getting cancer. This is backed by lots of research.
Studies prove colonoscopies are a powerful tool in cancer prevention. Regular screenings can cut down cancer cases and deaths a lot.
The Effectiveness of Colonoscopies in Cancer Prevention
Colonoscopies are a top choice for stopping colorectal cancer. They help find and remove polyps before they turn into cancer. This makes them very effective in preventing the disease.
Research Studies and Statistical Evidence
Many studies prove colonoscopies work well against colorectal cancer. They show that screenings can cut the risk of getting this cancer by 40-50%. This is because they catch and remove polyps early.
Statistical evidence also backs up the benefits of colonoscopies. Places with more screenings have fewer cases of colorectal cancer. This shows how important regular screenings are.
Reduction in Colorectal Cancer Incidence and Mortality
Colonoscopies have a big impact on cancer rates. They find cancer early and remove polyps that could become cancer. This helps lower both the number of new cases and deaths from cancer.
Regular screenings lead to fewer deaths from colorectal cancer. This proves how effective colonoscopies are in fighting cancer.
Major Cancer Organizations’ Endorsements
Big names like the American Cancer Society and the U.S. Preventive Services Task Force support colonoscopies. They say adults should start screenings at 45. This is key for catching cancer early.
These groups’ support shows how important colonoscopies are for our health. By following colonoscopy guidelines, we can lower our risk of colorectal cancer a lot.
Colonoscopy vs. Alternative Screening Methods
When it comes to finding colorectal cancer early, we need to look at colonoscopy and other options. Each has its own strengths and might be better for different people.
Colonoscopy is very good at finding cancer. But, other methods might be better for some. Let’s see what these alternatives are like.
Fecal Immunochemical Tests (FIT) and Stool DNA Tests
FIT and stool DNA tests are easy to use and don’t hurt. They check for hidden blood or DNA changes in your stool. They’re great for those who don’t want a more invasive test.
FIT is very good at finding cancer and is suggested for yearly checks. Stool DNA tests can spot blood and genetic signs of cancer or polyps too.
Virtual Colonoscopy: Benefits and Limitations
Virtual colonoscopy uses CT scans to see the colon. It’s less scary than regular colonoscopy and doesn’t need sedation.
But, it’s not perfect. It might miss small polyps or flat growths. If it finds polyps, you might need a regular colonoscopy to have them removed.
Flexible Sigmoidoscopy and Its Restricted View
Flexible sigmoidoscopy looks at the lower colon with a camera on a tube. It’s less invasive than colonoscopy but only checks a part of the colon.
This means it might miss growths or cancer in the upper colon. So, it’s not as thorough as colonoscopy.
In short, colonoscopy is key for cancer screening, but other methods are good too. Knowing what each can do helps people choose the best for their health.
Updated Screening Guidelines: Starting at Age 45
The age for colonoscopy screening has been lowered to 45. This change is due to more colorectal cancer cases in younger people. It’s a step towards catching cancer early and preventing it.
Reasons Behind the Lowered Screening Age
The age change from 50 to 45 is based on new data. The says it’s key for catching cancer early. More people in their 40s are getting diagnosed with colorectal cancer.
Screening Frequency Recommendations
People at average risk should start screening at 45 and keep going until 75. The timing of screenings varies by the test type. For example, colonoscopies are needed every 10 years if results are normal.
But, those with a family history or other risk factors might need more tests. It’s best to talk to a doctor about your screening schedule. They can help figure out what’s right for you.
Risk Factors Requiring Earlier or More Frequent Screening
Some risk factors mean you might need to screen earlier or more often. These include:
- A family history of colorectal cancer or polyps
- A personal history of colorectal cancer or certain genetic syndromes
- A history of inflammatory bowel disease
If you have these risk factors, talk to your doctor about your screening options. They can help find the best plan for you.
Knowing the new guidelines and your own risk factors helps us fight colorectal cancer together.
The Alarming Rise of Colorectal Cancer in Younger Adults
Recent studies show a worrying trend: colorectal cancer is increasing in younger adults. This change challenges the old idea that the disease mainly affects older people.
Changing Demographics of Colorectal Cancer
Colorectal cancer’s demographics are changing. Young adults, often in their 20s, 30s, or 40s, are getting diagnosed more often. Data shows that the number of cases in younger adults is growing. Many cases are found when the cancer is already advanced.
Potential Causes Behind the Increase in Young-Onset Cases
Several factors might be causing more young people to get colorectal cancer. Changes in diet, lifestyle, and environmental factors are thought to play a part. Genetic predispositions and other health conditions also might contribute.
- Dietary Factors: Eating too much processed food and not enough fiber might raise the risk.
- Lifestyle Factors: Being inactive and being overweight are also seen as risk factors.
- Genetic Predispositions: Having a family history or certain genetic syndromes can increase the risk.
Why Early Detection Is Critical for Younger Patients
Early detection is key for treating colorectal cancer effectively. For younger patients, finding cancer early can greatly improve their life and chances of survival. Screening, like colonoscopies, can spot and remove precancerous polyps before they turn cancerous.
|
Age Group |
Recommended Screening |
Benefits of Early Detection |
|---|---|---|
|
45 and above |
Regular colonoscopy |
Removal of precancerous polyps, early treatment |
|
Younger adults with risk factors |
Earlier screening as recommended by a healthcare provider |
Improved survival rates, reduced risk of advanced cancer |
We need to adapt to the changing face of colorectal cancer. By understanding the risks and taking action, we can lower the disease’s impact on younger adults.
Are Colonoscopies Safe? Addressing Common Concerns
Colonoscopies are mostly safe, but there are risks and complications to know about. It’s important to understand the risks, sedation options, and what happens after the procedure.
Understanding the Actual Risk of Complications
Research shows colonoscopy complications are rare but can happen. The risk of serious issues like perforation or bleeding is less than 1%. Certain factors, like age or health conditions, can raise this risk.
A study in the Journal of Clinical Gastroenterology found a 0.35% rate of major complications in over 20,000 colonoscopies. This highlights the need to talk about your specific risks with your doctor.
Sedation Options and Pain Management
Sedation makes colonoscopies more comfortable. There are different sedation levels, from minimal to deep sedation, and sometimes general anesthesia. The right sedation depends on your health, anxiety, and the procedure’s complexity.
- Minimal Sedation: You stay awake and can follow commands.
- Moderate Sedation: You’re drowsy but can respond to commands or touch.
- Deep Sedation: You’re not easily woken but can respond to pain.
Good pain management is key for a successful colonoscopy. Sedation helps reduce discomfort during the procedure. Any discomfort after is usually short-lived.
Recovery Time and Post-Procedure Effects
Recovery from a colonoscopy is usually quick, with most people back to normal in a day. But, sedation effects can last hours, so have someone drive you home.
Minor side effects like bloating or mild cramps are common but short-lived. Serious issues like severe pain or heavy bleeding are rare but need immediate medical attention.
“The key to a safe and successful colonoscopy lies in understanding the risks and taking steps to minimize them. By choosing a qualified healthcare provider and following pre- and post-procedure instructions carefully, patients can significantly reduce their risk of complications.”
By addressing common concerns and understanding safety measures, patients can feel more confident about this screening.
Preparing for Your Colonoscopy: What to Expect
Knowing what to expect during a colonoscopy can help reduce anxiety. We’re here to guide you through each step. This way, you’ll feel informed and ready for your colonoscopy.
The Bowel Preparation Process
Bowel preparation is key for a clear view during the colonoscopy. It involves a clear liquid diet and laxatives. This helps clean your bowel.
You’ll start by eating a clear liquid diet before your colonoscopy. This diet includes:
- Clear broths
- Plain gelatin
- Clear juices (such as apple or white grape)
- Black coffee or tea (without cream or sugar)
You’ll also take laxatives to clean your bowel. These can be powders, tablets, or liquids. It’s important to follow your healthcare provider’s instructions carefully for effective bowel preparation.
Dietary Restrictions Before the Procedure
Dietary restrictions are important for colonoscopy preparation. They help ensure your colon is clean for the exam. You’ll usually be told to avoid solid foods for at least 24 hours before.
|
Food Type |
Allowed |
Not Allowed |
|---|---|---|
|
Liquids |
Clear broths, clear juices |
Milk, creamy soups |
|
Foods |
Plain gelatin, popsicles |
Solid foods, nuts, seeds |
Tips for Making Preparation More Comfortable
Preparing for a colonoscopy can be tough, but there are ways to make it easier. Drinking plenty of clear liquids is key. Here are some colonoscopy tips to help:
- Prepare your medications in advance and take them as directed.
- Use a straw when drinking laxatives to minimize contact with your teeth.
- Stay near a bathroom during the bowel preparation process.
- Bring a book or other entertainment to distract you during downtime.
The Screening Gap: Why Only 61.4% of Eligible Americans Get Tested
Colonoscopies are key in preventing colorectal cancer. Yet, only 61.4% of eligible Americans get screened. This is short of the goal of 72.8% set by the Centers for Disease Control and Prevention.
Barriers to Reaching the National Target
Several factors lead to low screening rates. We need to tackle these barriers to boost colonoscopy rates.
- Lack of awareness about colorectal cancer and the importance of screening
- Fear of the procedure or its preparation
- Limited access to healthcare services
- Cultural and socioeconomic factors influencing health behaviors
Common Reasons People Avoid Colonoscopies
Knowing why people shy away from colonoscopies is key. Some common reasons include:
|
Reason |
Percentage |
|---|---|
|
Fear of pain or discomfort |
40% |
|
Embarrassment about the procedure |
25% |
|
Lack of awareness about the procedure |
20% |
|
Cost concerns |
15% |
Strategies to Increase Screening Rates
To close the screening gap, we need a variety of strategies. Some effective methods include:
- Public awareness campaigns to educate people about the importance of colonoscopy screening
- Improving access to screening services, focusing on underserved communities
- Patient education and counseling to ease fears and clear up misconceptions
- Implementing reminder systems to encourage timely screening
By tackling these barriers and using these strategies, we can increase screening rates. This will help reduce colorectal cancer cases.
Understanding Colonoscopy Results and Follow-Up Care
Colonoscopy results give you insights into your colon and rectum’s health. These results can greatly affect your care and health path.
Interpreting Different Types of Findings
Your colonoscopy results can show several things. You might see normal results, adenomatous polyps, or cancerous lesions. Normal results mean no issues were found. Adenomatous polyps are growths that could lead to cancer but can be removed. Cancerous lesions are growths that could be dangerous.
What Happens When Polyps Are Found
If polyps are found, they are usually removed for testing. Removing polyps, like adenomatous ones, helps prevent cancer. The biopsy will show if the polyps are benign or if they could be cancerous. Your doctor will then plan your next steps.
Getting news about polyps can be scary. But finding and removing polyps is key to stopping cancer. Your healthcare team will help you and support you every step of the way.
Recommended Surveillance Intervals Based on Results
The time until your next colonoscopy depends on your current results. If everything looks good, you might not need another for 10 years. But if polyps are found, your next colonoscopy will be sooner. For example, if you have adenomatous polyps, you might need a follow-up in 3 to 5 years.
Following the recommended schedule is important for catching problems early. We’re here to help you through every step of your care. Understanding your results and following your care plan are key to keeping your colon and rectum healthy.
Cost and Insurance Considerations for Colonoscopies
It’s important for patients to know about the cost and insurance for colonoscopies. The cost can be a big worry, but knowing what insurance covers can help. This knowledge can ease some of the financial stress.
Insurance Coverage Under the Affordable Care Act
The Affordable Care Act (ACA) makes sure colonoscopies are covered by insurance. This is for people at average risk and meet certain age and frequency guidelines. It aims to make preventive care more accessible by lowering costs. But, it’s key to check your insurance plan details as they can differ.
For example, if polyps are removed during a colonoscopy, it might not be covered as a preventive service. This could change what your insurance pays for. It’s best to talk to your insurance about what’s covered and what might cost extra.
Out-of-Pocket Expenses to Anticipate
Even with the ACA, patients might face extra costs under certain conditions. For instance, if a biopsy is done or if more procedures are needed, there could be extra charges. Also, costs for the facility, doctor, and pathology can add up.
To avoid surprise bills, patients should:
- Check their insurance coverage before the procedure.
- Ask about any extra costs for the colonoscopy.
- Know the billing process and what charges to expect.
Resources for Uninsured or Underinsured Patients
For those without insurance or with poor coverage, there are ways to get affordable colonoscopies. Community health centers, non-profit groups, and some hospitals offer help. They might have financial aid or fees based on income. Patients can also look at for affordable screening options.
We know cost is a big factor in health choices. By understanding insurance and looking for help, patients can make better decisions. Our goal is to help everyone get the screenings they need, no matter their financial situation.
High-Risk Groups: When Standard Guidelines Aren’t Enough
Not everyone faces the same risk of colorectal cancer. Some groups, because of their family history, genetic makeup, or health issues, are at higher risk. For these people, following the usual screening guidelines might not be enough to prevent colorectal cancer.
Family History of Colorectal Cancer or Polyps
Having a family history of colorectal cancer or polyps raises your risk. If a first-degree relative, like a parent or sibling, had colorectal cancer, you’re at higher risk. Early screening is key to catch problems before they grow into cancer.
If you have a family history, talk to your doctor about when to start screening. They can help figure out the best schedule for you.
Genetic Syndromes That Increase Cancer Risk
Genetic syndromes like Familial Adenomatous Polyposis (FAP) and Lynch Syndrome greatly increase cancer risk. FAP causes many polyps in the colon and rectum, starting in the teens. Lynch Syndrome raises the risk of colorectal and other cancers.
Genetic testing can spot these syndromes early. This allows for early monitoring and treatment. We stress the need for genetic counseling for families with these conditions to understand their risks and options.
Inflammatory Bowel Disease and Cancer Surveillance
People with inflammatory bowel disease (IBD) face a higher risk of colorectal cancer. The risk grows with longer IBD duration, family history of colorectal cancer, and extensive colitis.
Regular colonoscopies are advised for IBD patients to watch for dysplasia and cancer. Following a surveillance programcan lead to better outcomes by catching problems early.
We help IBD patients create a personalized surveillance plan. This ensures they get the care they need to manage their risk effectively.
Liv Hospital’s Approach to Colonoscopy and Colorectal Cancer Prevention
Liv Hospital leads in preventing colorectal cancer. We use the latest technology and protocols. Our goal is to provide top-notch healthcare through our colonoscopy and patient care services.
State-of-the-Art Protocols and Technology
We use the newest colonoscopy technology for quality care. Our advanced protocols help find and stop colorectal cancer early. Some of these technologies include:
- High-definition colonoscopy for clear views
- Narrow-band imaging for better polyp detection
- Advanced polypectomy for safe removal of growths
Patient-First Ethos and Ethical Care
At Liv Hospital, we put our patients first. We aim to make colonoscopy as comfortable and stress-free as possible. We do this by:
- Keeping patients informed and educated
- Offering sedation based on each patient’s needs
- Creating a supportive environment that values patient dignity
Continuous Quality Improvement Initiatives
We always look to improve our quality. We update our protocols based on new research and best practices. Our efforts include:
- Training and professional growth for our staff
- Joining international quality improvement programs
- Using patient feedback to improve our services
By using the latest technology, focusing on patient care, and striving for quality, Liv Hospital aims to make a big difference in preventing and detecting colorectal cancer early.
The Future of Colorectal Cancer Screening and Prevention
Colorectal cancer screening is on the verge of a big change. New technologies and methods are being developed. These advancements are making screening more effective and less invasive.
Emerging Technologies and Less Invasive Options
New screening methods are being explored. These include advanced imaging and biomarkers to find cancer early. For example, blood-based screening tests can spot cancer-related genetic material in the blood.
Artificial intelligence (AI) and machine learning (ML) are also being used. They help analyze data and images from colonoscopies. This makes finding problems faster and more accurate than before.
Advances in Colonoscopy Techniques
Colonoscopy is a key screening tool, and it’s getting better. New technologies like high-definition imaging and narrow-band imaging help spot polyps and cancer early. Also, disposable colonoscopy devices make the procedure safer for patients.
|
Technology |
Description |
Benefits |
|---|---|---|
|
High-Definition Imaging |
Enhanced visualization during colonoscopy |
Improved detection of polyps and early cancer |
|
Narrow-Band Imaging |
Specific wavelength illumination for better tissue characterization |
Enhanced differentiation between benign and malignant tissues |
|
Disposable Colonoscopy Devices |
Single-use devices for colonoscopy |
Reduced risk of infection, improved patient safety |
The Promise of Blood-Based Screening Tests
Blood-based tests are a big step forward in detecting colorectal cancer. They look for biomarkers in the blood linked to cancer. This could lead to earlier detection and easier screening.
Multi-cancer early detection tests are also being developed. They can spot several cancers, including colorectal cancer, from one blood sample. This could change how we screen for cancer, making it simpler and more accessible.
Conclusion: Taking Action Against a Preventable Cancer
Colorectal cancer is a disease we can prevent. Colonoscopy screening plays a key role in stopping it. By understanding its importance and taking action, we can lower the number of cases.
Liv Hospital is all about top-notch healthcare. We focus on how colonoscopy helps prevent colorectal cancer. Our advanced methods and technology help find and remove early signs of cancer, making prevention possible.
Colonoscopy is a powerful tool against colorectal cancer. With the screening age now 45, it’s vital to get checked. This way, we can fight the growing threat of colorectal cancer together.
At Liv Hospital, we support our patients every step of the way. We offer detailed care and advice on preventing colorectal cancer. We urge everyone to talk to their doctor about when to get screened.
FAQ
What is a colonoscopy and how does it prevent rectal cancer?
A colonoscopy lets doctors see inside the colon and rectum. They look for polyps, cancer, and other issues. It stops rectal cancer by finding and removing polyps before they turn cancerous.
Are colonoscopies safe?
Yes, colonoscopies are safe when done by skilled doctors. Though rare, risks like bleeding or perforation can happen.
What are the benefits of colonoscopy screening?
Colonoscopy screening finds colorectal cancer early, when it’s easier to treat. It also removes polyps that could become cancer. This lowers the risk of getting colorectal cancer and dying from it.
How often should I get a colonoscopy?
How often you need a colonoscopy depends on your risk factors. For most, it’s every 10 years starting at 45. Your doctor will tell you if you need it more often.
What are the risks of colonoscopy?
Colonoscopies are mostly safe. But, there are risks like bleeding, perforation, and reactions to sedation. These are rare, though.
Can I get a colonoscopy if I have a family history of colorectal cancer?
Yes, a family history of colorectal cancer might mean you need to get screened earlier or more often. Your doctor will decide based on your risk.
How do I prepare for a colonoscopy?
To prepare for a colonoscopy, you’ll need to clean out your colon with a bowel prep. You’ll also follow dietary restrictions and other instructions from your doctor.
What happens if polyps are found during a colonoscopy?
If polyps are found, they’re usually removed and biopsied. How often you need to come back for another colonoscopy depends on the polyps’ type, size, and number.
Is colonoscopy screening covered by insurance?
Yes, insurance usually covers colonoscopy screening without extra costs for those at average risk, starting at 45. This is thanks to the Affordable Care Act.
What are the alternatives to colonoscopy screening?
Other screening options include fecal immunochemical tests (FIT), stool DNA tests, virtual colonoscopy, and flexible sigmoidoscopy. But, colonoscopy is the best way to screen for colorectal cancer.
Can colonoscopy detect other conditions beside colorectal cancer?
Yes, colonoscopy can find other issues like inflammatory bowel disease, diverticulosis, and angiodysplasia, in addition to cancer and polyps.
How long does it take to recover from a colonoscopy?
Recovery from a colonoscopy is usually quick, with most people feeling back to normal in a day. But, sedation effects can last longer, and some might feel bloated or uncomfortable.
References:
- Centers for Disease Control and Prevention (CDC). (2025). Trends in colorectal cancer incidence among younger adults in the United States. Preventing Chronic Disease, 22(Issue 25_0175). Retrieved from https://www.cdc.gov/pcd/issues/2025/25_0175.htm
- RWJBarnabas Health. (2025, March). 45 is the new 50 for colorectal cancer screening. Retrieved from https://www.rwjbh.org/blog/2025/march/45-is-the-new-50-for-colorectal-cancer-screening/
- Colorectal Cancer Alliance. (n.d.). Facts & statistics. Retrieved from https://colorectalcancer.org/basics/facts-and-statistics
- National Colorectal Cancer Roundtable (NCCRT). (n.d.). 80% in every community. Retrieved from https://nccrt.org/our-impact/80-in-every-community/
- American Cancer Society. (n.d.). Key statistics for colorectal cancer. Retrieved from https://www.cancer.org/cancer/types/colon-rectal-cancer/about/key-statistics.html
- Siegel, R. L., Miller, K. D., Fedewa, S. A., Ahnen, D. J., Meester, R. G., Barzi, A., & Jemal, A. (2017). Colorectal cancer statistics, 2017. CA: A Cancer Journal for Clinicians, 67(3), 177–193. https://doi.org/10.3322/caac.21395 (PMC article) Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495412/
- Arnold, M., Sierra, M. S., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2017). Global patterns and trends in colorectal cancer incidence and mortality. The Lancet, 390(10107), 846–859. https://doi.org/10.1016/S0140-6736(12)61649-4