
Many people wonder about Extracorporeal Membrane Oxygenation (ECMO) and its link to open heart surgery. It’s important to know that ECMO is not a surgery. Instead, it’s a critical care support system.
ECMO helps when a patient’s heart or lungs can’t work right. It provides the needed oxygen and blood flow. This therapy is key in cardiac surgery for some patients (0.4% to 3.7%).
With more heart and lung transplants, the need for ECMO grows. It’s essential for patients and families to understand ECMO’s role. This knowledge helps them navigate complex cardiac care.
Key Takeaways
- ECMO is a life-support therapy, not a surgical procedure.
- It’s used when a patient’s heart or lungs are failing.
- ECMO supports patients after major cardiac surgery.
- The need for ECMO is rising with increasing heart and lung transplants.
- ECMO is used in a small percentage of cardiac surgery patients.
What Is ECMO and How Does It Work?

Extracorporeal Membrane Oxygenation, or ECMO, is a lifesaving treatment for severe heart or lung failure. It works by taking some blood from the body to an ECMO machine. There, the blood gets oxygen and gets rid of carbon dioxide before returning to the patient.
Definition of Extracorporeal Membrane Oxygenation
ECMO is a system that temporarily takes over the heart and lungs’ functions. It’s for patients with severe but possibly reversible heart or lung failure. This system lets the heart and lungs rest and recover while the patient is supported.
The Core Components of an ECMO System
The ECMO system has several key parts that work together. These include:
- A cannula or access device to divert blood from the patient
- A pump to propel the blood through the circuit
- An oxygenator, often referred to as an artificial lung, where gas exchange occurs
- A heat exchanger to maintain the patient’s blood temperature
- Monitoring systems to track the patient’s condition and the ECMO circuit’s performance
The setup can change based on whether the patient needs VA ECMO for the heart or VV ECMO for the lungs.
|
Component |
Function |
|---|---|
|
Cannula |
Access device for diverting blood |
|
Pump |
Propels blood through the ECMO circuit |
|
Oxygenator |
Facilitates gas exchange (oxygen in, CO2 out) |
|
Heat Exchanger |
Maintains patient’s blood temperature |
Temporary Life Support vs. Surgical Intervention
Many people think ECMO is like open-heart surgery. But it’s actually a temporary life-support measure, not a surgery. It helps patients recover or get further treatment.
ECMO can be used with surgery, but its main goal is to support the patient’s vital functions. This allows the heart and lungs to recover.
ECMO vs. Open Heart Surgery: Key Differences

ECMO and open heart surgery are two different ways to treat heart problems. Open heart surgery directly fixes the heart. ECMO, on the other hand, helps the heart work better by supporting it.
Defining Traditional Open Heart Procedures
Open heart surgery means opening the chest to work on the heart. It includes fixing arteries, transplanting hearts, and replacing valves. This surgery is big and takes a lot of time to recover from.
For a long time, open heart surgery was key for treating serious heart issues. But, it’s risky, mainly for those who are already sick or have other health problems.
How ECMO Functions as Support Instead of Surgery
ECMO, or Extracorporeal Membrane Oxygenation, is a therapy for when the heart or lungs fail. It uses cannulae to move blood to a machine outside the body. This machine makes the blood oxygen-rich and pumps it back in.
ECMO is not a fix for the heart like surgery is. It’s a way to help the heart and lungs rest and get better. It’s used in many critical care situations, like when the heart or lungs are severely failing.
When Both Interventions Work Together
ECMO and open heart surgery can be used together. For example, ECMO helps patients who had heart surgery but are struggling afterward. This shows how ECMO and surgery can work together to treat serious heart issues.
|
Aspect |
ECMO |
Open Heart Surgery |
|---|---|---|
|
Purpose |
Supportive care for heart/lung failure |
Surgical repair or replacement of heart structures |
|
Nature of Intervention |
Non-surgical, cannulation-based |
Surgical, involving opening the chest |
|
Recovery Time |
Varies, often shorter than open heart surgery |
Typically longer due to surgical trauma |
|
Usage Scenario |
Critical care, cardiac/respiratory failure |
Complex heart diseases requiring surgical intervention |
It’s important to know the differences between ECMO and open heart surgery. This helps doctors make the best choices for their patients. By understanding when to use each, doctors can give the best care possible.
Types of ECMO Support Systems
ECMO is versatile, with different setups for various patient needs. It helps with heart failure and severe breathing problems. Each setup is designed for specific situations.
Veno-Arterial (VA) ECMO for Cardiac Support
Veno-Arterial (VA) ECMO helps patients with severe heart failure. It uses both a vein and an artery. This way, the ECMO can help the heart pump.
VA ECMO is great for those waiting for a heart transplant or needing help after heart surgery.
The benefits of VA ECMO are:
- It directly supports the heart by increasing its output.
- It can help both the heart and lungs if they fail together.
- It can help patients wait for a heart transplant or recover.
Veno-Venous (VV) ECMO for Respiratory Support
Veno-Venous (VV) ECMO helps patients with severe breathing problems. It uses two veins to oxygenate blood before returning it to the body. VV ECMO is best for severe lung failure, like ARDS, when usual breathing methods don’t work.
|
Feature |
VA ECMO |
VV ECMO |
|---|---|---|
|
Cannulation Sites |
Vein and Artery |
Two Veins |
|
Primary Support |
Cardiac |
Respiratory |
|
Clinical Use |
Heart Failure, Post-cardiotomy Shock |
ARDS, Severe Respiratory Failure |
Hybrid Configurations and Their Applications
In complex cases, hybrid ECMO setups are used. They mix VA and VV ECMO or add more sites for better support. These setups meet the unique needs of each patient, supporting both heart and lungs.
Hybrid ECMO is key when patients have heart and lung failure. It lets doctors tailor care for better results.
The ECMO Machine: Technology That Mimics Heart-Lung Function
Extracorporeal Membrane Oxygenation (ECMO) technology has changed critical care. It mimics heart-lung function. This system is key for patients needing heart or lung support.
The ECMO machine is a complex device. It temporarily takes over the heart and lungs’ functions. This lets these organs rest and recover.
The Oxygenator: Creating the Artificial Lung
The oxygenator is a key part of the ECMO machine. It acts as an artificial lung. It exchanges oxygen and carbon dioxide in the blood outside the body.
Oxygenator Functionality:
- Removes carbon dioxide from the blood
- Adds oxygen to the blood
- Maintains optimal blood gas levels
Pumps, Circuits, and Blood Flow Management
The ECMO circuit has a pump that moves blood. This ensures blood keeps flowing. The pump’s speed and flow rate are adjusted to meet the patient’s needs.
|
Component |
Function |
|---|---|
|
Pump |
Propels blood through the ECMO circuit |
|
Oxygenator |
Exchanges oxygen and carbon dioxide |
|
Heat Exchanger |
Regulates blood temperature |
Monitoring Systems and Safety Features
The ECMO machine has advanced monitoring and safety features. These ensure patient safety. They include:
- Pressure sensors to monitor circuit pressure
- Blood gas analyzers for real-time monitoring
- Alarm systems for detecting circuit issues or patient distress
These features help healthcare providers quickly respond to any changes. This ensures the best care and reduces risks.
ECMO Cannulation: The Access Procedure Explained
Understanding ECMO cannulation is key to grasping this life-saving therapy. It’s the method to get into a patient’s blood vessels for Extracorporeal Membrane Oxygenation (ECMO) support.
Central vs. Peripheral Cannulation Approaches
There are two ways to do ECMO cannulation: central or peripheral. Central cannulation goes straight to the heart, usually through the chest. It’s used when other methods won’t work or in certain heart surgeries. Peripheral cannulation uses veins in the legs or neck. It’s less invasive.
Choosing between central and peripheral depends on the patient’s health and why ECMO is needed. Peripheral cannulation is often preferred because it’s less risky.
Step-by-Step Cannulation Process
The ECMO cannulation process has key steps:
- Preparation: The patient is checked, the site is prepared, and all tools are ready.
- Access: The chosen spot is reached, often with ultrasound to avoid problems.
- Cannula Insertion: The cannula is put in the vessel, and its position is checked.
- Securing the Cannula: The cannula is fixed to stay in place.
- Initiation of ECMO: ECMO starts, and the patient’s reaction is watched closely.
Surgical Considerations During ECMO Initiation
When starting ECMO, several surgical points are important. These include managing blood thinners, avoiding blood vessel damage, and watching for any issues with the cannula.
A team effort is vital for ECMO cannulation. Surgeons, doctors, and other experts work together to give the best care.
Primary Indications for ECMO Therapy
In intensive care units around the world, ECMO is a key support for patients with severe heart or lung problems. It’s used when usual treatments don’t work well enough.
Cardiac Failure Scenarios Requiring Support
ECMO is vital for those with severe heart failure. This includes cardiogenic shock, severe myocarditis, or heart failure after surgery. It helps keep blood flowing and organs working.
ECMO helps in several ways:
- Support during acute cardiac decompensation
- Bridge to recovery or further interventions like heart transplantation
- Stabilization of patients awaiting surgical intervention
Respiratory Failure and ARDS Management
For those with severe lung failure, like ARDS, ECMO is a lifesaver. It takes over lung work, letting lungs rest and recover while keeping oxygen levels up.
|
Condition |
ECMO Configuration |
Primary Benefit |
|---|---|---|
|
Severe ARDS |
Veno-Venous (VV) ECMO |
Lung rest and recovery |
|
Cardiogenic Shock |
Veno-Arterial (VA) ECMO |
Cardiac support and circulatory assistance |
Post-Cardiotomy Support Following Heart Surgery
ECMO is also used after heart surgery, when patients can’t get off the heart-lung machine or have heart failure. It’s key for helping them recover.
Starting ECMO after surgery depends on several things:
- Hemodynamic instability
- Inability to wean from cardiopulmonary bypass
- Severe cardiac dysfunction post-surgery
ECMO Contraindications and Limitations
Using ECMO requires careful thought about its limits and when it’s not a good choice. It’s a complex treatment that needs a detailed look at the patient’s health and possible risks.
Absolute Contraindications to Consider
Some conditions make ECMO too risky or pointless. These include:
- Severe irreversible brain damage: Patients with serious and permanent brain injury can’t use ECMO.
- Advanced cancer or other terminal conditions: ECMO is not usually suggested for those with late-stage cancer or other serious illnesses.
- Severe aortic regurgitation: This issue can make ECMO less effective because of blood flowing back into the heart.
A leading expert says, “If there are absolute contraindications, it’s important to rethink if ECMO is right for the patient.” This shows how key it is to choose patients carefully.
Relative Contraindications and Risk Factors
Some conditions make ECMO riskier but don’t rule it out. These include:
- Age and comorbidities: Older patients or those with many health issues might face more risks with ECMO.
- Bleeding risks and anticoagulation challenges: Patients at high risk of bleeding or who can’t safely take blood thinners might struggle with ECMO.
- Prolonged mechanical ventilation: Patients on a ventilator for a long time might have a harder time with ECMO.
A study found that “selecting and managing patients carefully is key to good ECMO results.” This shows the importance of weighing risks and benefits.
The Critical Risk-Benefit Assessment Process
Starting ECMO means looking at the good and bad sides. This involves a team of doctors, including cardiologists and surgeons, to make the right call.
“The risk-benefit check should think about the patient’s health, chance of getting better, and if ECMO can really help,” as guidelines say. This careful thinking is vital for using ECMO wisely.
In short, knowing when ECMO is not right is key. By looking at all the facts and weighing risks and benefits, doctors can help patients the best they can.
Post-Cardiotomy ECMO: Support After Open Heart Surgery
ECMO therapy is key for patients after heart surgery who struggle with breathing or heart issues. It’s used for those who face serious problems after surgery. This is called post-cardiotomy ECMO.
Incidence Rates: Understanding the Statistic
Research shows that about 0.4% to 3.7% of heart surgery patients need ECMO. This shows how different patients and surgeries can be. A study found that the need for ECMO can change based on the surgery and the patient’s health.
Check outa study on ECMO outcomes for more details.
Mortality Rates and Survival Challenges
Even though ECMO can save lives, it has high death rates. The patients’ health and the surgery’s success play big roles. We need to think about these when we talk about ECMO’s success.
Management Strategies for Optimal Outcomes
To help more patients survive, we need a team effort. This includes picking the right patients, starting ECMO on time, and managing it well. It’s also important to adjust ECMO settings, handle blood thinners, and prevent problems.
By using these methods, we can help more patients and lower death rates from post-cardiotomy ECMO.
Understanding ECMO Survival Rates
ECMO therapy has shown promising results in improving survival rates for patients with severe cardiac or respiratory failure. It’s essential to understand the current statistics, challenges, and factors that influence patient outcomes.
Current Survival Statistics and Trends
Recent studies have provided valuable insights into ECMO survival rates. According torecent research, the survival rates for ECMO patients have been steadily improving. This is due to advancements in technology and clinical practices.
To better understand the current survival statistics, let’s examine the data:
|
ECMO Type |
Survival Rate |
In-Hospital Mortality |
|---|---|---|
|
Veno-Arterial (VA) ECMO |
33-40% |
60-67% |
|
Veno-Venous (VV) ECMO |
50-60% |
40-50% |
The 60-67% In-Hospital Mortality Challenge
In-hospital mortality for post-cardiotomy ECMO patients averages 60–67%. This presents a significant challenge. A study notes, “The high mortality rate associated with ECMO therapy highlights the need for careful patient selection and management strategies”
This high mortality rate shows the complexity of ECMO therapy. It emphasizes the need for:
- Careful patient selection
- Advanced management strategies
- Continuous monitoring and improvement of ECMO practices
Factors That Influence Patient Outcomes
Several factors influence ECMO survival rates, including:
- Underlying Condition: The primary reason for ECMO initiation significantly impacts survival rates.
- Type of ECMO: Veno-Arterial (VA) and Veno-Venous (VV) ECMO have different survival rates due to their distinct applications.
- Clinical Management: The expertise of the ECMO team and the quality of care provided play critical roles in patient outcomes.
By understanding these factors and continually improving ECMO practices, we can work towards better survival rates for patients undergoing this life-supporting therapy.
Common Complications of ECMO Therapy
Extracorporeal Membrane Oxygenation (ECMO) therapy comes with risks. It can cause mechanical and patient-related complications. It’s important for healthcare providers to know about these issues to manage them well.
Mechanical and Circuit-Related Complications
ECMO therapy uses complex machinery and circuits. These can malfunction or cause problems. Some mechanical issues include:
- Pump failure: Though rare, it can be very serious and needs quick action.
- Oxygenator failure: The oxygenator is key. Failure can mean poor gas exchange.
- Circuit thrombosis: Thrombosis in the circuit can cause embolic events and circuit failure.
Patient-Related Complications and Risks
Patients on ECMO face various complications. These are due to their condition and the therapy’s invasive nature. Common complications include:
- Bleeding: The anticoagulation needed for ECMO increases bleeding risk, which can be deadly.
- Infection: The invasive ECMO cannulation and long therapy duration raise infection risk.
- Renal failure: ECMO patients are at risk for acute kidney injury, possibly needing renal replacement therapy.
Strategies for Preventing and Managing Complications
To reduce ECMO therapy risks, healthcare providers use several strategies:
- Close monitoring: Watching the ECMO circuit and patient closely helps catch problems early.
- Anticoagulation management: Managing anticoagulation therapy is key to avoid both thrombosis and bleeding.
- Prophylactic measures: Preventing infection is vital, with strict sterile technique and regular cannula site care.
Understanding ECMO therapy complications and using prevention and management strategies can improve patient outcomes.
The Multidisciplinary ECMO Team
A well-coordinated ECMO team is key for top-notch patient care. ECMO therapy’s complexity calls for teamwork. It involves many healthcare pros with specific roles.
Key Team Members and Their Specialized Roles
The ECMO team is made up of different professionals, including:
- ECMO Specialists: Doctors skilled in ECMO management and fixing issues.
- Perfusionists: Experts who run and keep the ECMO circuit working.
- Nurses: They’re trained in ECMO care and watch over patients closely.
- Respiratory Therapists: They handle patient breathing and oxygen needs.
- Surgeons: They help with putting in the ECMO cannula and do surgeries.
Each team member has their own area of expertise. This ensures ECMO patients get all-around care.
Training Requirements and Certification Standards
ECMO team members get thorough training and certifications. These programs teach:
- How to manage and fix the ECMO circuit.
- How to check on patients and monitor them.
- What to do in emergencies and crisis situations.
Keeping certifications up means ongoing education and practice. This keeps the team current with ECMO methods.
Coordination in High-Stakes Scenarios
Good teamwork is vital, more so in urgent situations like:
- Circuit failures or problems.
- Patients getting worse or having a heart attack.
Through regular training and practice, we get better at quick and effective action. This helps us give our patients the best care possible.
“The success of ECMO therapy is not just about the technology; it’s about the people behind it – a dedicated team working together to save lives.”
— ECMO Specialist
ECMO in Transplantation Medicine
ECMO is a key life-support therapy in transplantation medicine. It acts as a bridge for patients waiting for heart and lung transplants. This technology is vital for patients with severe heart or lung failure, keeping them stable until a donor organ is found.
Bridge to Heart and Lung Transplantation
ECMO acts as a bridge to transplantation by supporting patients waiting for heart and lung transplants. It’s very important for those on the transplant list but facing a long wait due to organ shortages.
- Stabilizes critically ill patients
- Supports patients through the evaluation process for transplantation
- Maintains organ function until a transplant can be performed
Management Challenges During Waiting Periods
Managing patients on ECMO during the transplant wait is challenging. Issues include:
- Preventing complications like bleeding or infection
- Keeping the ECMO circuit working well and providing enough support
- Monitoring and managing the patient’s overall health
Overcoming these challenges needs a multidisciplinary approach. This involves cardiologists, surgeons, intensivists, and more.
Success Rates and Patient Selection Criteria
The success of ECMO as a bridge to transplantation depends on choosing the right patients. Important factors include:
- The patient’s underlying condition and chance of recovery
- The likelihood of successful transplantation
- Any reasons why ECMO might not be suitable
Research shows ECMO can be effective in bridging to transplantation. Survival rates vary based on the patient and their situation.
Recent Advancements in ECMO Technology
Extracorporeal Membrane Oxygenation (ECMO) technology has seen big changes. These changes have made cardiac and respiratory support better. Now, ECMO therapy is more effective and helps patients more.
Innovations Improving Patient Outcomes
New ECMO tech has improved patient care. It controls blood flow and oxygen better. For example, new oxygenators work better, cutting down on complications.
Also, advanced monitoring systems track patient health and ECMO performance in real-time. This helps doctors act fast if something goes wrong, keeping patients safer.
Key Innovations:
- Advanced oxygenators for improved gas exchange
- Real-time monitoring systems for enhanced patient safety
- More precise control over blood flow and oxygenation
Miniaturization and Enhanced Portability
ECMO tech is getting smaller and more portable. This makes it easier to use in different places, like intensive care units and during transport.
Smaller ECMO systems need less blood and have lower priming volumes. This makes setup easier and cuts down on bleeding risks.
|
Feature |
Traditional ECMO |
Miniaturized ECMO |
|---|---|---|
|
Size and Portability |
Larger, less portable |
Compact, highly portable |
|
Priming Volume |
Higher |
Lower |
|
Bleeding Risk |
Higher due to larger circuit |
Lower due to reduced circuit size |
Future Directions in ECMO Development
ECMO tech is getting even better. We’ll see more ways to help patients and make ECMO therapy better. Future plans include using artificial intelligence and making ECMO circuits more friendly to the body.
“The future of ECMO lies in its ability to adapt to the needs of individual patients, leveraging technology to provide personalized care.” -ECMO Specialist
These new steps will make ECMO therapy even more effective. It will also help more patients.
Global Trends in ECMO Utilization
Worldwide, ECMO use has grown a lot. This shows its key role in treating severe heart and lung problems. It’s becoming more known as a lifesaver in critical care.
The Significant Year-on-Year Increase in ECMO Cases
ECMO use has jumped by 75% each year. This shows its bigger role in healthcare. It’s due to better technology, clearer guidelines, and more trust in its benefits.
This increase isn’t just because more people need ECMO. It also shows it’s becoming a common treatment for many serious conditions. So, hospitals around the world are getting ready to handle more ECMO cases.
Regional Variations in ECMO Accessibility
Even with more ECMO use, access varies by region. This is because of different healthcare setups, money issues, and who’s trained to use it.
|
Region |
ECMO Centers per Million Population |
Key Challenges |
|---|---|---|
|
North America |
5-7 |
Cost, Training, Equipment Maintenance |
|
Europe |
4-6 |
Regulatory Frameworks, Funding |
|
Asia-Pacific |
2-4 |
Infrastructure, Awareness, Training |
Economic and Resource Considerations
ECMO therapy is expensive. It costs a lot for the machines, staff, and care after treatment. Managing these costs is key, mainly in places with tight budgets.
To manage ECMO well, you need to plan money and train staff. Also, making ECMO protocols better can help patients and cut down on problems.
Liv Hospital’s Approach to ECMO Excellence
Liv Hospital is dedicated to ECMO excellence. We use the latest technology and a team approach. This ensures our patients get the best care possible.
World-Class Protocols and Academic Standards
Our ECMO program follows rigorous academic standards and evidence-based practices. We keep up with international guidelines and update our protocols regularly. This ensures our patients get safe and effective care.
We maintain high academic standards to encourage learning and improvement. Our team gets regular training to stay updated on ECMO care.
Multidisciplinary Services and Patient Outcomes
At Liv Hospital, we believe in a multidisciplinary approach for ECMO care. Our team includes experts from cardiology, intensive care, and cardiovascular surgery. This teamwork helps us meet our patients’ complex needs and improve outcomes.
We offer a range of support services, like psychological counseling and rehabilitation programs. These services help patients throughout their ECMO journey, from start to finish.
Vision for Advanced Cardiac Support
Liv Hospital is committed to advancing ECMO therapy and improving patient outcomes. We invest in innovative technologies and techniques. Our goal is to lead in ECMO care, providing the latest treatments for complex cardiac conditions.
We aim to make a big difference in our patients’ lives and those of their families. Our drive for excellence and innovation pushes us to keep improving and expanding our services.
Conclusion: The Future of ECMO in Cardiac Care
Extracorporeal Membrane Oxygenation (ECMO) has become a key therapy in cardiac care. It is used more often in different heart conditions. This shows its growing role in medicine.
ECMO’s future looks bright with new tech and more uses. We’re seeing smaller, more portable ECMO systems. These changes could lead to better care and more access for patients.
ECMO will be even more important in heart care soon. It will help with complex cases like support after heart surgery and as a bridge to heart transplants. As healthcare evolves, so will the need for ECMO.
At Liv Hospital, we’re all about top-notch heart care. We use the newest ECMO tech and methods. Our team works hard to support patients from around the world who need advanced treatments.
FAQ
What is ECMO and how does it work?
ECMO, or Extracorporeal Membrane Oxygenation, is a therapy that helps the heart and lungs rest. It pumps blood outside the body to add oxygen and remove carbon dioxide. Then, it returns the blood to the body.
Is ECMO the same as open heart surgery?
No, ECMO and open heart surgery are not the same. ECMO is a supportive therapy used before, during, or after surgery. Open heart surgery, on the other hand, involves opening the chest to work on the heart.
What are the different types of ECMO?
There are two main types of ECMO. Veno-Arterial (VA) ECMO supports both the heart and lungs. Veno-Venous (VV) ECMO mainly supports the lungs. Hybrid configurations can also be used based on the patient’s needs.
What is the ECMO cannulation process?
The ECMO cannulation process involves putting tubes into the blood vessels. This diverts blood to the ECMO machine. The method used depends on the patient’s condition and the ECMO type.
What are the primary indications for ECMO therapy?
ECMO is used for cardiac and respiratory failure, and after heart surgery. It also acts as a bridge to heart or lung transplant.
What are the contraindications for ECMO?
ECMO is not suitable for severe neurological damage or irreversible multi-organ failure. It’s also not recommended for advanced age, significant health issues, or long-term ventilation before ECMO.
What are the common complications associated with ECMO?
ECMO can lead to mechanical issues like pump failure or circuit clotting. Patient-related complications include bleeding, infection, and limb ischemia. Preventive and management strategies are key to reduce these risks.
What is the survival rate for patients on ECMO?
Survival rates for ECMO patients vary. They depend on the underlying condition and the reason for ECMO. Studies show in-hospital mortality rates between 60-67%.
How is ECMO used in transplantation medicine?
ECMO supports patients waiting for heart or lung transplant. It helps manage challenges during the waiting period. This can improve transplant outcomes.
What advancements have been made in ECMO technology?
ECMO technology has seen advancements. These include miniaturization and portability of machines, as well as better oxygenators and circuit designs. These improvements aim to enhance patient outcomes.
How is ECMO utilized globally?
ECMO use has increased globally, with a 75% rise in cases each year. Accessibility and economic factors vary by region, affecting ECMO adoption worldwide.
References
National Center for Biotechnology Information. Evidence-Based Medical Insight. Retrieved from https://pmc.ncbi.nlm.nih.gov/articles/PMC8451085/