Last Updated on November 26, 2025 by Bilal Hasdemir

If you’re dealing with neck pain from a herniated or slipped disc, you might have thought about epidural steroid shots. This option is a minimally invasive way to find relief.
At Liv Hospital, we focus on making sure you know all about these injections. Our team is here to give you detailed information and help you understand this treatment.
Epidural steroid injections (ESI injection in neck) put corticosteroid medication around a pinched nerve. This is done in the epidural space. It’s used to treat back pain from a herniated disc or cervical radiculopathy.
Key Takeaways
- Epidural steroid injections can help with neck pain from herniated discs.
- Guidelines suggest not getting more than three or four injections a year per spinal level.
- The treatment involves placing corticosteroid medication around a pinched nerve.
- It’s a minimally invasive option for managing pain from herniated discs.
- It’s important to educate patients about the safety and effectiveness of epidural steroid shots.
What Are ESI Injections for Cervical Herniated Discs?

Epidural Steroid Injections (ESIs) are a key treatment for cervical herniated discs. They help reduce pain and discomfort from cervical radiculopathy. This condition happens when nerves in the neck get compressed or irritated.
The Purpose of Epidural Steroid Injections
ESIs aim to cut down inflammation around nerve roots. Steroids are injected into the epidural space around the spinal cord. This helps lessen swelling and irritation that cause pain.
Doctors say ESIs are a valuable treatment for cervical radiculopathy. They offer significant pain relief and improve quality of life.
Cervical Radiculopathy and Disc Herniation
Cervical radiculopathy happens when a herniated disc in the neck presses or irritates a nerve root. This leads to pain, numbness, or weakness in the arm. It can make daily activities hard.
ESIs are great for managing cervical radiculopathy symptoms. They target the inflammation source.
How ESIs Target Nerve Inflammation
ESIs deliver corticosteroids directly to the epidural space. This brings the anti-inflammatory medication close to the affected nerve roots. It reduces nerve inflammation, easing pain and discomfort.
“The localized delivery of steroids via ESIs allows for potent anti-inflammatory effects with minimal systemic side effects,” says a doctor. This shows how effective ESIs are.
Most guidelines suggest not having more than three or four ESIs a year per spinal level. This ensures ESIs are used safely and effectively for cervical radiculopathy and disc herniation. Understanding ESIs helps patients make better care choices.
Types of ESI Injection in Neck Procedures

It’s important to know about the different ESI injections for neck pain. There are two main methods: the transforaminal and interlaminar approaches.
Transforaminal Approach
The transforaminal method injects steroid medication into the neural foramen. This is where the nerve root exits the spinal canal. It targets the affected nerve precisely, which can lead to better pain relief. This method is great for those with specific nerve root irritation.
Interlaminar Approach
The interlaminar method injects steroid medication into the epidural space. It goes through the space between two vertebrae. This is used for more general pain or when the exact nerve root is unclear. It’s good for patients with pain at multiple levels.
Differences in Technique and Application
Choosing between these methods depends on several factors. These include the patient’s condition, pain location and severity, and the doctor’s expertise. Knowing these differences helps pick the right treatment.
Let’s compare these methods:
| Characteristics | Transforaminal Approach | Interlaminar Approach |
| Injection Site | Directly into the neural foramen | Into the epidural space through the interlaminar space |
| Precision | High precision targeting specific nerve roots | Less precise, broader coverage |
| Indications | Ideal for specific nerve root irritation | Suitable for generalized pain or multiple level disc involvement |
Understanding ESI injections helps doctors tailor treatments for each patient. This can lead to better pain management.
Recommended Frequency Guidelines for Cervical ESIs
Cervical epidural steroid injections (ESIs) are key in treating cervical radiculopathy. But how often can they be given? The right frequency is important to manage pain well and avoid risks. We’ll look at the guidelines and what healthcare providers consider when deciding how often to give cervical ESIs.
Standard 3-4 Injections Per Year Guideline
Most guidelines say to limit ESIs to three or four per year per spinal level. This is because too many injections can cause side effects. We follow these guidelines to ensure our patients get the best treatment with the least risk.
After each injection, we wait at least two weeks, sometimes up to a month, before deciding on more injections. This wait lets us see if the treatment worked and plan the next steps.
Special Cases for Up to 6 Injections
In some cases, doctors might give up to six injections per year. This is for patients who have greatly improved with previous injections and where the benefits are greater than the risks. We carefully look at each patient’s situation to decide the best treatment plan.
“The decision to proceed with additional injections should be based on a thorough assessment of the patient’s condition and response to previous treatments.”as emphasized in pain management guidelines and clinical practice recommendations.
Single Spinal Level vs. Multiple Level Considerations
The number of spinal levels treated also affects how often ESIs are given. Patients with multiple level disc herniations might need more injections. We tailor our treatment plans based on each patient’s unique situation.
| Spinal Levels | Recommended Injections Per Year | Assessment Period |
| Single Level | 3-4 | 2 weeks to 1 month |
| Multiple Levels | Up to 6 (in special cases) | 2 weeks to 1 month |
By following these guidelines, we can offer our patients safe and effective treatments for cervical radiculopathy.
Optimal Timing Between Neck ESI Treatments
Knowing when to have ESI treatments is key for treating cervical herniated discs. At our place, we stick to what science says to help our patients the most.
The Two-Week Minimum Waiting Period
We say wait at least two weeks before getting more ESI shots. This lets the first treatment work fully and helps us see how it’s doing.
Key benefits of this approach include:
- Allowing the steroid to take full effect
- Reducing the risk of over-treatment
- Enabling a more accurate assessment of treatment efficacy
One-Month Assessment Window
Even though we wait two weeks, we really check how ESI treatments are working in one month. This lets us see if pain, movement, and overall health have gotten better.
When we look at how well treatments are working, we think about:
- Pain relief and symptom reduction
- How well you can move and function
- Any side effects or problems
Research on Peak Effectiveness Timing
Research shows ESI treatments work best one to three months after getting them. This helps us plan when to do more shots to help our patients the most.
By planning when to do ESI treatments, we make them more effective and safer. We aim to give our patients the best results, balancing relief and safety in their care.
Evaluating ESI Effectiveness Before Additional Injections
To make sure we’re giving the best care, we check how well ESIs work. We look at how they reduce inflammation and ease symptoms from cervical disc herniation. This involves a detailed look at several factors.
Pain Relief Assessment Methods
Checking if pain relief works is key. We use tools like the Visual Analog Scale (VAS) or the Numeric Rating Scale (NRS) to measure pain changes. These tools show us how much pain relief ESIs bring.
- Patient-reported outcomes: Patients tell us about their pain, helping us see if the treatment works.
- Pain diary: A pain diary tracks pain changes over time, giving us insight into treatment success.
Functional Improvement Indicators
We also look at how well a patient can function. This means checking if they can do daily tasks without pain. We look at:
- Range of motion: We measure how well the neck and surrounding areas move.
- Muscle strength: We check the strength of neck and upper limb muscles.
- Daily activity performance: We see if patients can do everyday tasks without pain or discomfort.
When to Consider Alternative Treatments
If ESIs don’t help enough, we look at other options. This might include:
- Physical therapy: A special exercise program to boost mobility and strength.
- Minimally invasive procedures: Options like radiofrequency ablation or spinal cord stimulation might be considered.
- Surgical intervention: Sometimes, surgery is needed to fix the root cause of symptoms.
By carefully checking ESI results and thinking about each patient’s needs, we create a treatment plan that works best. This helps improve their quality of life.
Long-Term Safety Considerations for Repeated ESIs
Repeated ESIs can help patients with cervical radiculopathy a lot. But, it’s important to know the long-term effects. We need to weigh the good and bad sides of epidural steroid injections.
Cumulative Steroid Exposure Risks
Using steroids over and over again is a big worry. Steroids can affect the whole body. They might mess with the adrenal glands, cause osteoporosis, or make infections more likely.
Tissue and Bone Density Concerns
Using steroids too much can weaken tissues and bones. It might even cause osteoporosis or fractures. We watch patients who get many ESIs closely to avoid these problems.
| Potential Risks | Description | Mitigation Strategies |
| Osteoporosis | Weakening of bones due to steroid use | Bone density monitoring, calcium supplements |
| Tissue Weakening | Potential for tissue degradation with repeated injections | Careful injection technique, limited number of injections |
| Adrenal Suppression | Suppression of adrenal function due to cumulative steroid exposure | Monitoring adrenal function, tapering steroid doses |
Adrenal Function Impact
The adrenal glands make important hormones. Too much steroid use can hurt their work. We check how well the adrenal glands are working in patients getting many ESIs.
Current Research on Long-Term Effects
Research is key to knowing how ESIs affect us over time. Studies look at how steroids affect our bodies.
As we learn more, we can give better care. We aim to find the right balance between the benefits and risks of ESIs.
Patient-Specific Factors Affecting ESI Frequency
Many factors influence how often someone with cervical disc herniation needs ESIs. At our institution, we know every patient is different. So, we tailor the ESI frequency to meet each person’s unique needs.
Age and Overall Health Considerations
A patient’s age and health are key in deciding ESI frequency. Older patients or those with health issues might need a careful approach to ESIs. We make sure treatment is safe and effective for them.
For example, older adults might have conditions like diabetes or osteoporosis. These can affect how often they need ESIs. Our healthcare team carefully looks at each patient’s health to make the best decisions.
Severity of Disc Herniation
The severity of the disc herniation also plays a big role. Patients with severe herniations might need more frequent injections. Those with milder cases might need fewer.
| Severity of Herniation | Typical ESI Frequency |
| Mild | 1-2 injections per year |
| Moderate | 2-3 injections per year |
| Severe | 3-4 injections per year |
Response to Previous Injections
How a patient responds to previous ESIs is very important. If they get a lot of relief and function better, we might stick with the same plan.
“The effectiveness of ESIs in managing cervical radiculopathy is well-documented, and a patient’s response to previous injections is a strong indicator of future success.”
Journal of Pain Research
Concurrent Treatments and Medications
Other treatments and medications can also change how often ESIs are needed. For example, those doing physical therapy or taking certain meds might need to adjust their ESI schedule.
Our healthcare team looks at the whole treatment plan when figuring out ESI frequency. This way, we make sure our patients get the best care possible.
Insurance and Cost Considerations for Multiple ESIs
Insurance and cost are key when thinking about getting multiple ESI injections for cervical herniated discs. It’s important for patients to know these details to make good choices about their treatment.
There are many insurance and cost factors to consider for multiple ESI injections. These include what’s covered, if you need approval first, and what documents you’ll need to show.
Typical Coverage Limitations
How much insurance covers for ESI injections can vary. Some plans might cover up to three injections a year. Others might have stricter limits.
- Annual limits: Some insurance plans have yearly limits on ESI injections.
- Medical necessity: You’ll need to show that you really need the injections. This might mean showing what treatments you’ve tried before.
Prior Authorization Requirements
Getting approval from your insurance before getting ESI injections is common. This means you need to get okayed by your insurance before you can get the treatment.
To get through the approval process well:
- Review insurance policy: Know what your insurance policy says about getting approval.
- Gather necessary documentation: Make sure you have all the medical records and documents ready for your approval request.
- Follow up: Keep an eye on your approval request to make sure it gets approved on time.
Documentation Needed for Additional Injections
For those needing more than one ESI injection, keeping good medical records is key. You’ll need to have:
- Treatment history: A full record of any ESI injections you’ve had before, including when and how they went.
- Symptom documentation: Keep track of your symptoms and how they affect your daily life.
- Response to treatment: Keep records of how well you’ve responded to the injections you’ve had so far.
Understanding insurance and cost can help patients get the ESI injections they need. We’re here to help patients understand their insurance and make sure they get the care they need.
Conclusion: Balancing Relief and Safety with Neck ESI Treatments
ESI injections in the neck can help those with herniated discs. Knowing how often to get them and what types are best is key. This knowledge helps patients choose the right care for themselves.
We want our patients to be well-informed. This way, they get treatments that fit their specific needs. We aim for effective pain relief without risking their safety.
Our team is committed to caring for each patient personally. We strive to find the right balance between relief and safety with neck ESI treatments. This approach helps our patients live better lives.
FAQ
How often can you get epidural steroid injections in the neck for a herniated disc?
You can usually get epidural steroid injections (ESIs) in the neck up to three or four times a year. But, sometimes, you might get up to six injections. This depends on your condition and how well you respond to the treatment.
What are the different types of ESI injections that can be used for cervical herniated discs?
There are two main types of ESI injections for the neck. The transforaminal method targets the nerve root affected by the herniated disc. The interlaminar method injects steroids into the space between the vertebrae.
How long should you wait between ESI treatments?
It’s best to wait at least two weeks between ESI treatments. This lets us see how well the previous injection worked. It also helps avoid risks from too much steroid use.
How is the effectiveness of ESI injections evaluated?
We check how well ESI injections work by looking at pain relief and how well you can function. Our doctors use special tools and their own judgment to decide if more injections are needed or if you should try something else.
What are the possible risks of getting ESI injections more than once?
Getting ESI injections too often can harm your tissues, bones, and adrenal glands. Our team watches over you closely and follows the best practices to keep these risks low.
Can insurance cover multiple ESI injections?
Insurance coverage for ESI injections can vary. It depends on your insurance company and policy. Our team helps you understand what your insurance covers, including any limits or requirements for more injections.
How do patient-specific factors influence the frequency of ESI injections?
We consider your age, health, and how severe your disc herniation is when deciding on ESI injections. Our doctors tailor the treatment plan to fit your unique needs and situation.
Are there alternative treatments to ESI injections for herniated discs?
Yes, there are other treatments for herniated discs. These include physical therapy, pain medicines, and surgery. Our doctors will talk to you about these options and choose the best one for you.
References
- Yoon, S. M., Kim, J.-W., & Lee, D.-J. (2023). A systematic review and meta-analysis: efficacy of cervical epidural steroid injection for cervical radicular pain. Pain Physician. https://pubmed.ncbi.nlm.nih.gov/36608007/
- Ben Yamin, R., Singh, V., Parr, A. T., Conn, A., Diwan, S., & Abdi, S. (2009). Systematic review of the effectiveness of cervical interlaminar epidural injections in the management of chronic neck pain. Pain Physician, 12, 137-157. https://painphysicianjournal.com/current/pdf?article=MTE3NQ%3D%3D&journal=47