Last Updated on November 26, 2025 by Bilal Hasdemir

At Liv Hospital, we know how tough chronic back and neck painPain After Resection Surgery: What to Expect can be. That’s why we offer epidural corticosteroid injections. They help by putting anti-inflammatory medicine right where it’s needed.
After getting an epidural steroid injection, you might wonder when the pain will ease up. The time it takes for pain relief can vary. Some people start feeling better in just a few days, while others might take a bit longer.
We’ll walk you through what to expect during your recovery. This includes what happens right after the procedure and any possible side effects. We want to help you get ready and understand what to expect.
Key Takeaways
- Epidural corticosteroid injections deliver anti-inflammatory medication directly to the epidural space.
- The timeline for pain relief varies among individuals.
- Understanding the recovery process can help manage expectations.
- Liv Hospital provides complete guidance throughout your treatment journey.
- Recovery experiences can differ significantly from one person to another.
Types of Epidural Steroid Injections

There are many types of epidural steroid injections. Each is made for different parts of the spine and for different pain types. The right injection depends on where and why you’re in pain, and your health situation.
Cervical Epidural Injections
Cervical injections are for the neck. They help with pain from herniated discs, spinal stenosis, or nerve issues. The steroids go into the space around the spinal cord in the neck, giving targeted relief.
Thoracic Epidural Injections
Thoracic injections are for the mid-back. They’re used for pain in the thoracic spine. Though not as common, they can help with mid-back disc issues or stenosis.
Lumbar Epidural Steroid Injections
Lumbar injections are for the lower back. They’re great for sciatica, disc problems, and stenosis. Steroids in the epidural space around the lower spine can cut down inflammation and pain.
Caudal Epidural Injections
Caudal injections go into the caudal space, accessed through the sacral hiatus. They’re for chronic pain in the lower back and legs. They can help with disc issues, stenosis, and nerve problems.
A study found, “Epidural steroid injections have become a cornerstone in the management of radicular pain” (emphasis added). The different epidural injections offer tailored treatments. They help with pain and improve life quality.
The Timeline for ESI Pain Relief

Many patients wonder when they’ll feel relief after an epidural steroid injection. The time it takes for pain relief can vary. But, most people start feeling better within a few days.
The steroid in the injection needs time to work. It reduces inflammation and eases nerve pressure. We’ll look at how long it takes for pain relief to kick in. We’ll also talk about what can affect how fast you feel better.
Initial Response Period (3-7 Days)
The first signs of relief from an epidural steroid injection usually show up in 3 to 7 days. During this time, the steroid starts to work. It lessens inflammation and eases nerve pressure. People may notice their symptoms getting better, like less pain and more mobility.
Full Effect Timeline (Up to 2 Weeks)
While some people feel better in the first week, it can take up to 2 weeks for the full effect. This delay is because it takes time for the steroid to fully reduce inflammation and swelling around the nerves.
Factors Affecting Response Time
Several things can affect how fast you feel pain relief after an ESI. These include:
- The severity of the condition being treated
- The location of the injection (cervical, thoracic, lumbar, or caudal)
- The patient’s overall health and response to steroid medication
- Previous treatments or interventions the patient has undergone
Knowing these factors can help both patients and healthcare providers. It helps set realistic expectations and make better treatment choices.
| Factor | Impact on Response Time |
| Severity of Condition | More severe conditions may take longer to respond |
| Injection Location | Cervical injections may have a faster response than lumbar |
| Patient’s Overall Health | Healthier patients may respond more quickly |
Understanding the typical timeline for pain relief after an epidural steroid injection helps. It also helps know what can affect how fast you feel better. This way, patients can prepare better for treatment and manage their expectations.
Success Rates and Effectiveness of ESIs
Looking at the success rates of ESIs helps patients decide on their treatment. Epidural Steroid Injections are used to manage pain from different spinal issues. How well ESIs work can depend on the condition and the patient.
General Success Statistics
Research shows over half of patients see improvement after an ESI. The success rate is over 50%, but it can change based on the condition and the patient.
Some important stats on ESI success include:
- More than 50% of patients feel a lot of pain relief
- A big number of patients see better function
- Some patients might even have all their symptoms go away
Condition-Specific Outcomes
The success of ESIs can differ a lot based on the condition. For example:
- Herniated Discs: ESIs can help with pain and swelling from herniated discs.
- Spinal Stenosis: ESIs can help some patients with spinal stenosis, but the relief can vary.
- Degenerative Disc Disease: ESIs might give temporary relief for some with degenerative disc disease.
When ESIs May Not Provide Relief
Even though ESIs work for many, they might not help everyone. This includes:
- When the underlying condition doesn’t respond to steroid injections
- When there’s a lot of scar tissue or unusual anatomy
- For patients with certain health issues that make steroids risky
Knowing these points helps both patients and doctors make better choices about using ESIs.
Duration of Pain Relief from Epidural Injections
Knowing how long pain relief from epidural steroid injections lasts is key. The time can vary a lot, based on several factors. These include the condition being treated and how the patient reacts to the injection.
Typical Relief Periods
Pain relief from these injections can last from a few weeks to months. Some people might feel relief for a shorter time, while others for longer. This difference comes from how each person reacts to the steroid and their specific condition.
Variations in Duration Based on Condition
The type of condition being treated affects how long relief lasts. For example, those with herniated discs or spinal stenosis might see relief for different lengths of time. We’ll look at these differences in more detail.
| Condition | Typical Duration of Relief |
| Herniated Discs | 2-6 months |
| Spinal Stenosis | 3-12 months |
| Degenerative Disc Disease | 1-3 months |
Signs That Relief Is Diminishing
When the effect of the injection fades, symptoms can come back. It’s important to watch your pain levels and tell your doctor if they change. Signs that relief is fading include more pain, less mobility, or symptoms coming back.
Long-term Outcomes and Expectations
Some people get long-lasting pain relief from these injections, but others might need more treatments. It’s important to have realistic hopes and work with your doctor to plan for long-term pain management. Things that affect long-term results include the condition, overall health, and how well the first treatment worked.
Preparing for Your Epidural Steroid Injection
To get the most out of your epidural steroid injection, you need to prepare well. Preparing for this procedure involves several steps. These steps make sure the process is safe and works well.
Medical Evaluations and Tests
You’ll go through medical checks and tests before the injection. These might include looking at your medical history, a physical check-up, and some tests like blood work or imaging. It’s important to tell your healthcare provider about any medicines you’re taking and any allergies.
Medication Adjustments Before the Procedure
Your doctor might ask you to change or stop some medicines before the injection. This is often the case with blood thinners, as they can make bleeding more likely. Always do what your doctor tells you to do with your medicines to avoid risks.
Fasting Requirements
You might need to fast before the procedure, but this is not always the case. It depends on the type of sedation or if there’s a chance of complications. Your healthcare provider will tell you if you need to fast.
What to Bring on Procedure Day
On the day of your epidural steroid injection, bring any important medical records and a list of your medicines. It’s also a good idea to have a friend or family member with you. Wearing comfortable clothes and being ready can make things easier.
By following these steps, you can make sure your epidural steroid injection works well. This helps you recover better and manage your pain more effectively.
The ESI Procedure: What to Expect
Knowing what happens during an ESI procedure helps patients feel more at ease. An epidural steroid injection is often used to treat chronic pain in the spine.
Before the Injection
Before the epidural steroid injection, you’ll get a detailed medical check-up. This includes looking at your health history, current meds, and any allergies. You might also need some tests to see if the procedure is right for you.
On the day of the procedure, you’ll need to arrive ready. This means:
- Having someone with you, as you might not be able to drive right away
- Coming with clean, dry skin where the injection will be given
- Being ready to share your medical history and current health
During the Procedure
When you get the steroid injection into spine, you’ll be positioned correctly. This depends on the type of injection you’re getting. The area will be cleaned and numbed with a local anesthetic to make you more comfortable.
The actual injection is guided by fluoroscopy to place the steroid and anesthetic correctly. This part is quick, lasting just a few minutes.
| Procedure Step | Description |
| Preparation | Positioning, cleaning, and numbing the injection site |
| Injection | Using fluoroscopic guidance to inject the steroid and anesthetic mixture |
| Post-Injection | Monitoring for immediate reactions or side effects |
Immediate Post-Procedure Experience
After the epidural cortisone injection, you’ll be watched for any immediate side effects. You might feel some soreness at the injection site, but it’s usually short-lived.
It’s key to follow your healthcare provider’s post-procedure instructions. This might include:
- Avoiding hard activities for a while
- Watching for signs of infection or other issues
- Keeping up with follow-up appointments
Understanding the ESI procedure helps patients prepare for the treatment and recovery.
ESI Injection Recovery: The Complete Process
Knowing what to expect after an epidural steroid injection can help. It’s about understanding the different stages of recovery. This includes resting first and then slowly getting back to normal.
First 24 Hours After Injection
Right after the ESI, rest for at least 24 hours. This time is important for the steroid to work and to avoid side effects. Try to avoid hard work, lifting heavy things, and bending during this period.
Days 2-7 of Recovery
Once the first 24 hours are over, you can start doing more. But, listen to your body and don’t do too much too soon. Most people can do light things in a few days. But, avoid hard work or exercise for a week.
Gradual Return to Activities
Going back to normal slowly is important for a good recovery. It helps see if the ESI worked and keeps you safe. Don’t rush back to your usual life too fast.
When to Resume Normal Activities
How long it takes to get back to normal varies. It depends on your health, job, and what you’re treating. Usually, people can get back to normal in a week to ten days. But, always listen to your doctor’s advice.
To make the recovery process clearer, here’s a summary table:
| Recovery Stage | Recommended Activities | Activities to Avoid |
| First 24 Hours | Rest, light stretching | Strenuous activities, heavy lifting, bending |
| Days 2-7 | Gradual increase in light activities | Heavy physical labor, strenuous exercise |
| After Day 7 | Return to normal activities as advised by your healthcare provider | Activities that cause significant pain or discomfort |
By sticking to this recovery plan, you can get the most out of your ESI. It helps you feel better and live better.
Common Side Effects of Epidural Steroid Injections
Epidural steroid injections are generally safe but can have side effects. Knowing these can help patients prepare and know when to get medical help.
Temporary Side Effects
Most people feel some temporary side effects after an epidural steroid injection. These can include:
- Mild discomfort or soreness at the injection site
- Temporary numbness or tingling
- Mild headaches
- Facial flushing
These temporary side effects usually go away in a few days.
Steroid-Related Side Effects
The steroid in ESIs can cause more side effects, mainly with repeated use. These may include:
- Weight gain due to increased appetite
- Insomnia or sleep disturbances
- Mood changes, such as irritability or anxiety
- Fluid retention
Talking to your healthcare provider about these steroid-related side effects is important.
Rare but Serious Complications
Though rare, serious complications can happen with epidural steroid injections. These may include:
- Infection at the injection site
- Nerve damage or irritation
- Allergic reactions to the steroid or local anesthetic
- Bleeding complications, specially in patients on anticoagulant medications
It’s key to know these risks and get help right away if severe symptoms happen.
Understanding the side effects of epidural steroid injections helps patients make better choices. If you have concerns or questions, always talk to your healthcare provider.
When to Contact Your Doctor After an ESI
Knowing the signs of complications after an ESI is key for quick medical help. After getting an epidural steroid injection, watch how your body reacts. Know when to call your doctor.
Warning Signs of Complications
ESIs are usually safe, but some complications can happen. If you notice any of these symptoms, call your doctor right away:
- Severe or worsening pain at the injection site or spreading to other areas
- Signs of infection, like fever, redness, swelling, or discharge at the injection site
- Numbness or weakness in the legs or arms that doesn’t get better or gets worse
- Bowel or bladder issues, like losing control or trouble starting
- Allergic reactions, such as rash, itching, or trouble breathing
Follow-up Appointment Expectations
A follow-up visit is usually set after an ESI to check how it’s working and watch for problems. At this visit, your doctor will:
- Look at your pain levels and see how much relief you’re getting
- Check for any signs of complications or side effects
- Talk about more treatment if needed
Documenting Your Response to Treatment
Keeping a record of your symptoms and how you’re feeling after an ESI helps a lot. This can include:
- Tracking your pain levels with a pain diary
- Noting any changes in your symptoms or overall health
- Recording any side effects or complications
Being proactive and informed helps you get the best care after an ESI. This way, you can recover better.
Conclusion: Managing Expectations for Your ESI Recovery
Managing your expectations is key to a good epidural steroid injection (ESI) recovery. Knowing about the procedure, recovery, and possible side effects helps a lot. This way, patients can handle their treatment better.
Studies show ESI greatly improves pain, disability, and life quality for 24 months. A study on the National Center for Biotechnology Information website proves ESI’s effectiveness in chronic pain management. For more details, check out this resource.
Being well-informed and ready helps patients get the most out of their recovery. It’s about knowing when pain relief starts, possible side effects, and the need for follow-up care.
ESI recovery needs patience, understanding, and good care. By following the advice in this article, patients can have a smooth and successful recovery.
FAQ
What is an epidural steroid injection?
An epidural steroid injection is a procedure that uses corticosteroids to reduce inflammation. It’s done in the epidural space around the spinal cord to relieve pain.
How long does it take for an epidural steroid injection to work?
Most people feel relief within 3-7 days after the injection. The full effect is usually seen in about 2 weeks.
What are the different types of epidural steroid injections?
There are several types, like cervical, thoracic, lumbar, and caudal injections. Each targets a different part of the spine.
What is the success rate of epidural steroid injections?
The success rate is over 50%. But, it can vary based on the condition and individual factors.
How long does pain relief from epidural injections last?
Pain relief can last weeks to months. Some people may experience relief for longer periods.
What are the common side effects of epidural steroid injections?
Side effects include temporary pain at the site and steroid-related issues like weight gain. Rare but serious complications include infection or nerve damage.
How should I prepare for an epidural steroid injection?
You’ll need medical evaluations and tests. Adjust your medications and follow fasting instructions. Bring necessary items on the day of the procedure.
What can I expect during and after the ESI procedure?
You’ll be positioned on an X-ray table and receive local anesthesia. The injection is then administered. Afterward, you may feel some discomfort and will be monitored before being discharged.
When should I contact my doctor after an ESI?
Contact your doctor if you experience severe pain, numbness, or weakness. Also, if you have concerns about your recovery or response to treatment.
Can I resume normal activities after an ESI?
Yes, but follow your doctor’s guidelines. Avoid heavy lifting, bending, or strenuous activities for a while.
What are the signs that relief from epidural steroid injection is diminishing?
Signs include a gradual return of pain, decreased mobility, or increased discomfort. If you notice these, consult your doctor about further treatment.
Are there any long-term outcomes or expectations after ESI?
Long-term outcomes vary. Many people experience sustained relief, while others may need additional treatments or alternative therapies.
References
- Benyamin, R. M., Manchikanti, L., Parr, A. T., Singh, V., Falco, F. J., Buenaventura, R., & Simopoulos, T. T. (2012). The effectiveness of lumbar interlaminar epidural injections in managing chronic low back and lower extremity pain. Pain Physician, 15(4), E363-E404. https://pubmed.ncbi.nlm.nih.gov/22828692/