Last Updated on November 4, 2025 by mcelik

Nearly 1 in 5 adults in the United States deal with chronic pain. Many turn to diclofenac sodium topical gel for relief. But, Voltaren gel isn’t for everyone.

Diclofenac sodium topical gel is generally safe when used right. But, it can lead to serious side effects. These include heart attack, stroke, and bleeding in the stomach or intestines in some people.

It’s important to know who should not use it. People with heart problems or stomach issues might be at a higher risk.

Key Takeaways

• Diclofenac sodium topical gel can cause serious cardiovascular and gastrointestinal side effects.
• Individuals with a history of heart issues or GI bleeding should consult a doctor before use.
• Understanding the risks and proper usage is essential for safe treatment.
• Always follow the recommended dosage to minimize possible side effects.
• Consult a healthcare professional if you have concerns about using Voltaren gel.

Understanding Voltaren Gel and Its Active Ingredient

Voltaren gel, with diclofenac sodium, is a top choice for pain relief. Knowing its active ingredient and how it works is key to its benefits and risks.

What is Diclofenac Sodium?

Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID). It’s used to ease pain and reduce swelling. As Voltaren gel’s active ingredient, it’s absorbed through the skin to target pain areas.

Diclofenac sodium works by stopping the body’s production of prostaglandins. These substances cause pain and swelling. This makes it great for treating pain from arthritis and other inflammatory conditions.

How Voltaren Gel Works for Pain Relief

Voltaren gel applies diclofenac sodium directly to the pain site. This method offers localized relief without the side effects of oral NSAIDs. It’s a top pick for many because it targets pain and swelling effectively.

The gel’s design makes it easy to apply and quickly absorbed. This ensures the active ingredient gets to the pain source fast.

FDA Approval and Available Formulations

Voltaren gel has FDA approval for treating certain pains, like osteoarthritis. It comes in various strengths and forms. This lets doctors choose the best treatment for each patient.

It’s important for patients to follow the dosage and application guidelines for safety and effectiveness. The different forms available make it suitable for various pain levels and swelling.

Medical Conditions That Contraindicate Voltaren Gel Use

Some medical conditions make it risky to use Voltaren gel. This product, with diclofenac sodium, helps with pain. But, it’s not for everyone, mainly those with certain health issues.

Heart Disease and Cardiovascular Risks

Heart disease patients should be careful with Voltaren gel. Diclofenac, the main ingredient, can raise heart attack and stroke risks. Always talk to a doctor before using Voltaren gel if you have heart disease.

Kidney Disease and Renal Impairment

Those with kidney problems should be careful with Voltaren gel. NSAIDs, like diclofenac, can harm kidney function. It’s important to watch kidney function if you already have kidney issues.

History of Gastrointestinal Bleeding or Ulcers

Having had stomach bleeding or ulcers is a big no for Voltaren gel. NSAIDs, including diclofenac, can cause stomach problems. Don’t use Voltaren gel if you’ve had stomach bleeding or ulcers.

Asthma and Allergic Reactions to NSAIDs

People with asthma or NSAID allergies should be careful. Voltaren gel can make asthma worse. If you’re allergic to NSAIDs or aspirin, stay away from Voltaren gel.

Talking to a healthcare provider about your health before using Voltaren gel is key. This ensures it’s safe for you.

Pregnancy, Breastfeeding, and Voltaren Gel Safety

Women who are pregnant or breastfeeding should know about Voltaren gel’s safety. The main ingredient, diclofenac, is an NSAID. It can be risky during these times.

Risks During Different Trimesters of Pregnancy

Using Voltaren gel in the third trimester can be risky. Diclofenac can cause premature closure of the ductus arteriosus, a vital blood vessel in the fetus.

The risks change with each trimester: – In the first and second trimesters, the risk is lower, but caution is needed. – In the third trimester, the risks are higher, and other pain relief options are better.

Breastfeeding Considerations

Even though little diclofenac gets into breast milk, breastfeeding mothers should talk to their healthcare provider before using Voltaren gel. The effects on the baby, though rare, are something to think about.

Consideration	Details
Diclofenac in Breast Milk	Low levels detected, but caution advised
Healthcare Provider Consultation	Recommended before using Voltaren gel
Potential Infant Effects	Rare, but possible; monitoring advised

Fertility Concerns with NSAID Use

NSAIDs, like diclofenac in Voltaren gel, can affect fertility in women. Women trying to get pregnant or having trouble conceiving should talk to their healthcare provider about NSAID use.

NSAIDs can impact fertility in several ways: – They can affect ovulation. – They might delay ovulation. – It’s key to discuss other pain relief options with a healthcare provider.

Age-Related Restrictions for Voltaren Gel

It’s important to know about age limits for Voltaren gel. Age can affect how well this medicine works for pain.

Safety Concerns for Children and Adolescents

Voltaren gel is not for kids under 18. There’s not enough research on its safety and how well it works in young people. Kids and teens might be at risk because their bodies are changing and they might process drugs differently.

Caution is advised for teens near 18. A doctor needs to check if it’s safe for them.

Special Considerations for Elderly Patients

Older adults need special care with Voltaren gel. Their skin and health can change with age. Doctors might adjust how much they use and how to apply it to avoid bad side effects.

“Elderly patients are more susceptible to the systemic effects of NSAIDs, including Voltaren gel, due to decreased renal function and other age-related changes.”

Increased Risks in Adults Over 65

People over 65 face higher risks with Voltaren gel. They might get heart problems or stomach issues. It’s key for them to stick to the right dose and see their doctor regularly.

• Watch for heart problems like chest pain or trouble breathing.
• Look out for stomach issues like belly pain or dark stools.
• Tell your doctor about any skin problems or other side effects.

Knowing these age limits and taking the right steps can help people use Voltaren gel safely. Always talk to a doctor first.

Drug Interactions: Medications to Avoid While Using Voltaren Gel

It’s important to know which medications can interact with Voltaren Gel. This topical NSAID can mix with other drugs, leading to serious health issues.

Interactions with Blood Thinners and Anticoagulants

Using Voltaren Gel with blood thinners or anticoagulants can raise the risk of bleeding. Medications like warfarin are known to have such interactions. It’s vital to watch your condition closely if you’re using these together.

Combining with Other NSAIDs or Pain Relievers

Using Voltaren Gel with other NSAIDs or pain relievers can increase side effects. This includes stomach problems and kidney issues. Avoid using multiple NSAIDs unless a healthcare professional advises you to.

Effects on Blood Pressure Medications

Voltaren Gel may not work well with blood pressure medications. This is a big concern for people with high blood pressure.

Other Significant Drug Interactions

Other drugs that can interact with Voltaren Gel include certain antidepressants and diuretics. Always tell your healthcare provider about all your medications to avoid interactions.

Medication Type	Potential Interaction	Precaution
Blood Thinners/Anticoagulants	Increased risk of bleeding	Monitor closely, adjust dosage if necessary
Other NSAIDs/Pain Relievers	Enhanced risk of side effects	Avoid concurrent use unless advised by a healthcare professional
Blood Pressure Medications	Reduced effectiveness	Monitor blood pressure regularly

Knowing about these interactions helps you use Voltaren Gel safely. Always talk to your healthcare provider if you have concerns about drug interactions.

Common Side Effects of Voltaren Gel

Voltaren gel may cause side effects in some people. It’s usually safe, but knowing the possible side effects is important.

Skin Reactions and Dermatological Concerns

One common side effect is skin reactions where you apply Voltaren gel. You might see redness, itching, or dryness. In rare cases, you could get rashes or blistering.

It’s key to watch how your skin reacts. Stop using Voltaren gel if you have a bad reaction.

To avoid skin problems, follow the directions for using Voltaren gel. Don’t apply it to sensitive areas or under tight dressings without a doctor’s advice.

Systemic Side Effects

Even though Voltaren gel is applied to the skin, it can be absorbed into the blood. This can lead to side effects like stomach issues or heart problems.

Be aware of these risks, even more so if you have health issues that NSAIDs might make worse.

When Side Effects Require Medical Attention

Most side effects from Voltaren gel are mild and go away quickly. But, some need medical help. If you have severe skin reactions, serious stomach problems, or heart issues, get help right away.

If side effects don’t get better or get worse, talk to a doctor about keeping up with Voltaren gel.

Proper Application and Dosage Guidelines for Voltaren Gel

Knowing how to use Voltaren gel right is key for safe pain relief. It helps the active ingredient, diclofenac sodium, work best. This way, you get the most benefits with fewer side effects.

Recommended Application Techniques

To use Voltaren gel correctly, follow these steps:

• Wash and dry your hands before application.
• Apply a thin layer of gel to the affected area.
• Gently massage the gel into the skin until it’s fully absorbed.
• Wash your hands again after application, unless they are the treated area.

Tip: Avoid applying Voltaren gel to open wounds or irritated skin.

Dosage Limitations and Frequency

The right amount of Voltaren gel depends on the area size. Use 2-4 grams for the affected area, four times a day. But, don’t use more than 32 grams a day.

Area Size	Recommended Dose	Frequency
Small Area	2 grams	4 times a day
Medium Area	3 grams	4 times a day
Large Area	4 grams	4 times a day

Areas Where Voltaren Gel Should Not Be Applied

Voltaren gel should not be applied to:

• Open wounds or broken skin.
• Areas with skin irritation or infection.
• The eyes, mouth, or mucous membranes.
• Areas with a history of allergic reactions to NSAIDs.

Duration of Treatment Considerations

How long you use Voltaren gel should be decided by a doctor. Usually, it’s for up to two weeks. If your pain doesn’t go away, talk to your doctor for advice.

Long-Term Use Concerns and Possible Complications

It’s important to know the risks of using Voltaren gel for a long time. Voltaren gel helps with pain, but using it for a long time can cause problems.

Cardiovascular Risks with Extended Use

Using Voltaren gel for a long time may raise the chance of heart problems. This includes heart attacks and strokes. People with heart disease or at risk for it should be careful.

Cardiovascular Risks to Consider:

• Heart attack
• Stroke
• High blood pressure
• Heart failure

Gastrointestinal and Kidney Effects Over Time

Long-term Voltaren gel use can also harm the stomach and kidneys. Stomach problems like ulcers and bleeding can happen. Kidney damage is another risk due to how the drug affects the kidneys.

Potential Complication	Description
Gastrointestinal Ulcers	Long-term NSAID use can cause stomach ulcers and bleeding.
Kidney Damage	Diclofenac can affect kidney function, potentially leading to kidney damage.

Maximum Recommended Treatment Duration

A doctor should decide how long to use Voltaren gel. This depends on your health and how bad your pain is. Try to use it for as short a time as possible.

Following the right dosage and application is key to avoid long-term problems.

It’s vital to have regular check-ups with your doctor if you’re using Voltaren gel for a long time. They can watch for heart, stomach, and kidney issues.

Alternative Pain Relief Options for Those Who Cannot Use Voltaren Gel

There are many other ways to manage pain if Voltaren gel isn’t an option. People might choose these alternatives because of side effects, personal reasons, or other health issues.

Non-NSAID Topical Treatments

For those who can’t use NSAIDs like Voltaren gel, there are other topical treatments. These include:

• Topical capsaicin creams, which reduce pain signals to the brain.
• Arnica gel or cream, made from the arnica plant, for its anti-inflammatory effects.
• Topical creams or gels with menthol or eucalyptus, which cool the skin to ease pain.

Non-Pharmacological Pain Management Approaches

There are also non-medical ways to manage pain. These include:

1. Physical therapy, which uses exercises and techniques to improve mobility and reduce pain.
2. Acupuncture, an ancient method that uses thin needles to stimulate healing points on the body.
3. Cognitive-behavioral therapy (CBT), a psychological method that helps change how one perceives and responds to pain.

When to Consider Oral Medications Instead

In some cases, oral medications are needed for pain relief. Options include:

Oral Medication	Description	Considerations
Acetaminophen	A pain reliever that is not an NSAID, suitable for those who cannot take NSAIDs.	Should be used with caution in individuals with liver disease.
Oral NSAIDs	Similar to Voltaren gel but in oral form, for systemic pain relief.	May have gastrointestinal side effects; use under medical supervision.
Prescription pain medications	Stronger pain relievers for severe pain, including opioids or other prescription drugs.	Should be used under strict medical guidance due to the risk of dependency and side effects.

Always talk to a healthcare professional before changing your pain relief plan, including starting oral medications.

Conclusion: Making Informed Decisions About Voltaren Gel

It’s important to know the risks and benefits of Voltaren gel before using it. Certain health conditions, age limits, and drug interactions can affect its safety.

Always talk to a healthcare provider before starting treatment with Voltaren gel. They can help figure out if it’s right for you. They’ll look at your health history and what medicines you’re taking.

Being aware of the risks helps you use Voltaren gel safely. This way, you can get the most out of it without facing too many problems.

FAQ

References

1. Brunton, L., Hilal-Dandan, R., & Knollmann, B. C. (Eds.). (2023). Diclofenac. In Goodman & Gilman’s: The Pharmacological Basis of Therapeutics (14th ed.). McGraw Hill. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK557879/