
Bone cancer is a rare form of cancer that originates in the bones. Unlike cancer that has spread to the bones from other organs, primary bone cancer begins within the bone itself. It can develop in any bone in the body but is most commonly found in the long bones of the arms and legs. There are different types of bone cancer, with osteosarcoma, chondrosarcoma, and Ewing sarcoma being among the most common.
Bone Cancer Staging:

Bone cancer staging assesses how far the cancer has spread and informs the treatment plan. Staging considers the size of the tumor, whether it has invaded nearby tissues or lymph nodes, and if it has metastasized to other parts of the body.
Signs of Bone Cancer:
Common signs of bone cancer include persistent bone pain, swelling in the affected area, and, in advanced stages, an increased risk of fractures. These symptoms usually worsen over time and may also be accompanied by fatigue and unintended weight loss.
When to See a Doctor:
If you have ongoing bone pain, unexplained swelling, or other worrisome symptoms, consult a healthcare provider as soon as possible. Early diagnosis and treatment greatly increase the chances of successful outcomes.
Causes of Bone Cancer:
The exact cause of bone cancer is not fully understood. However, genetic factors, previous radiation therapy, and certain bone conditions may increase the risk. Ongoing research continues to investigate what leads to the development of bone cancer.
Types of Bone Cancer:
Bone cancer can develop from different types of bone cells, resulting in several distinct forms. Osteosarcoma arises from cells that form new bone, chondrosarcoma starts in cartilage-producing cells, and Ewing sarcoma usually affects both bone and surrounding soft tissue.
Bone Cancer Treatment:

Bone cancer treatment usually combines surgery, chemotherapy, and radiation therapy to achieve the best outcome. The specific approach depends on the cancer's type, stage, and location.
Surgery:Surgery is usually the main treatment for bone cancer. The primary aim is to remove the tumor while preserving as much healthy bone and function as possible. Limb-sparing procedures are often an option, but in some cases, amputation may be necessary to fully eliminate the cancer.
Chemotherapy: Chemotherapy uses medications to destroy or slow the growth of cancer cells. It can be given before surgery to shrink the tumor, after surgery to target any remaining cancer cells, or on its own for advanced cases of bone cancer.
Radiation Therapy: Radiation therapy uses high-energy beams to destroy cancer cells. It is often combined with surgery to lower the risk of the cancer returning, or used as palliative care to relieve pain and symptoms in advanced cases.
Targeted Therapy: Targeted therapy drugs focus on specific molecules or pathways that help cancer grow. These treatments are typically used when standard options are ineffective or as part of clinical trials.
Immunotherapy: Immunotherapy works by boosting the body's own immune system to fight cancer. While this approach has shown promise in several cancers, its effectiveness in treating bone cancer is still being studied through clinical trials.
Clinical Trials: Clinical trials provide access to innovative treatments and therapies that are not yet widely available. Participating in a clinical trial can help improve outcomes and expand future treatment options for people with bone cancer.
Anyone diagnosed with bone cancer should work closely with a specialized medical team to develop a treatment plan tailored to their unique needs and diagnosis.
Bone Cancer Survival Rate:
Bone cancer survival rates depend on factors such as the cancer type, stage at diagnosis, and the patient's overall health. Early detection and prompt, appropriate treatment greatly improve the chances of a positive outcome. In general, the five-year survival rate for bone cancer is about 70%.
Treatment for bone cancer can cause side effects, including fatigue, nausea, hair loss, and a higher risk of infection. The severity and type of side effects vary based on the treatment approach and individual patient factors. Healthcare providers work closely with patients to manage these effects and ensure the best possible care during treatment
* Liv Hospital Editorial Board has contributed to the publication of this content .
* Contents of this page is for informational purposes only. Please consult your doctor for diagnosis and treatment. The content of this page does not include information on medicinal health care at Liv Hospital .
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Frequently Asked Questions
Where Does Bone Cancer Usually Start:
Bone cancer most often begins in the extremities, such as the arms and legs, but it can also develop in other bones like the pelvis or spine. It originates in bone cells and can affect individuals of any age.
Who Is at Risk for Bone Cancer:
The exact risk factors for bone cancer are not fully known. However, factors that may increase risk include a family history of bone cancer, certain genetic conditions, previous radiation therapy, and bone diseases such as Paget's disease.
Can a Benign Bone Tumor Become Cancerous:
Most benign bone tumors do not become cancerous. However, in rare cases, some benign tumors can undergo malignant transformation and develop into bone cancer. Regular monitoring and medical evaluation of benign bone tumors are essential to detect any potential changes.