Hematology focuses on diseases of the blood, bone marrow, and lymphatic system. Learn about the diagnosis and treatment of anemia, leukemia, and lymphoma.
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Polycythemia Vera is a chronic malignancy, meaning that “recovery” is defined not by a cure, but by the achievement of stable disease control and the preservation of quality of life. The clinical course can span decades, requiring a lifelong partnership between the patient and the hematologist. Follow up care at Liv Hospital is focused on vigilant surveillance for disease progression, the management of long term treatment side effects, and the proactive handling of vascular health.
While many patients remain in the chronic phase for life, the disease has a natural tendency to evolve.
Over 15 to 20 years, roughly 15 to 20 percent of patients progress to myelofibrosis.
Transformation to Acute Myeloid Leukemia (AML) is the most feared complication.
Since thrombosis is the leading cause of death, cardiovascular health is paramount.
Long term use of cytoreductive agents requires specific monitoring.
The diagnosis of a chronic leukemia can be psychologically burdensome.
Pregnancy in PV is considered high risk due to the increased chance of miscarriage, placental thrombosis, and maternal clots.
Management: Ideally, pregnancy is planned. Hydroxyurea must be stopped months in advance due to teratogenicity. Interferon is the drug of choice for count control during pregnancy. Low dose aspirin and prophylactic low molecular weight heparin are often used to protect the pregnancy.
Choosing Liv Hospital for the management of Polycythemia Vera means placing your trust in a center that understands the complexity of Myeloproliferative Neoplasms. We do not simply treat high blood numbers; we manage the intricate physiology of the hematopoietic system. Our Hematology Department is equipped with state of the art molecular diagnostic capabilities, allowing for precise quantification of JAK2 allele burden to track disease depth. We offer a full spectrum of therapeutic options, from our dedicated therapeutic phlebotomy suite designed for patient comfort to access to the latest targeted therapies like Ruxolitinib and Ropeginterferon. Our multidisciplinary team includes cardiologists to manage vascular risk, dermatologists to monitor skin health, and high risk obstetricians for family planning. We are dedicated to transforming Polycythemia Vera from a life threatening diagnosis into a manageable chronic condition, empowering you to live a full and active life.
Send us all your questions or requests, and our expert team will assist you.
In the beginning, visits may be weekly to stabilize counts. Once stable, visits are typically every 3 to 6 months to monitor blood counts and check the spleen.
This is a measurement of how much of the JAK2 mutation is in your blood. Tracking this over time can tell doctors if the disease is expanding or shrinking in response to treatment.
Yes, phlebotomy is designed to cause iron deficiency to slow down red cell production. You should not take iron supplements unless directed by your hematologist, as this will counteract the treatment.
These are red blood cells that look like teardrops under a microscope. Seeing them suggests that the bone marrow is becoming scarred (fibrosis), making it hard for cells to get out.
Transplant is the only cure, but it carries high risks. It is usually reserved for younger patients whose disease has progressed to aggressive myelofibrosis or leukemia.
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Hematology
Hematology
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