Dermatology focuses on the health of the skin, hair, and nails. Learn about the diagnosis and treatment of acne, eczema, skin cancer, and cosmetic procedures.
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Diagnosis and evaluation of melanoma focus on identifying malignant changes as early as possible, determining the depth and extent of the lesion, and distinguishing melanoma from benign pigmented skin findings. Because melanoma can vary widely in appearance and may mimic harmless moles or other skin lesions, careful and structured evaluation is essential. Dermatologic assessment aims to confirm the diagnosis accurately while minimizing delay, as early-stage melanoma behaves very differently from advanced disease.
Evaluation does not rely on a single observation but rather on a combination of visual assessment, pattern recognition, and, when indicated, tissue examination.
Dermatology is the branch of medicine and surgery dedicated to the diagnosis, treatment, and prevention of diseases affecting the skin, hair, nails, and mucous membranes. As the skin is the largest and most visible organ of the human body, it serves as the first line of defense against injury and bacteria, as well as a window into the body’s overall health. A Dermatologist is a specialist physician trained to manage over 3,000 different conditions, ranging from cosmetic concerns like wrinkles to life-threatening diseases like melanoma.





Visual inspection is the first and most important step.
During examination, the dermatologist evaluates the lesion’s
• Size and shape
• Border definition
• Color uniformity or variation
• Surface features such as ulceration or bleeding
• Symmetry compared to surrounding moles
Special attention is paid to lesions that differ noticeably from others on the body, often described as the “ugly duckling” pattern.
History of change is a critical diagnostic clue.
Melanoma is often identified by its evolution rather than its appearance at a single point in time. Evaluation includes asking whether the lesion has
• Grown in size
• Changed in color or shape
• Become raised after being flat
• Developed new symptoms such as itching or bleeding
A documented change increases suspicion even if the lesion is small.
Enhanced visualization improves diagnostic accuracy.
Dermoscopy is a non-invasive technique that allows magnified examination of subsurface skin structures not visible to the naked eye. This tool helps identify patterns suggestive of melanoma and differentiate malignant lesions from benign moles.
Dermoscopy supports
• Earlier detection
• Reduced unnecessary biopsies
• Better assessment of lesion structure
It is widely used in dermatologic evaluation of pigmented lesions.
Tissue evaluation confirms the diagnosis.
A biopsy is performed when a lesion shows features suspicious for melanoma. The goal is to obtain a tissue sample that allows accurate microscopic assessment.
Biopsy is indicated when
• Clinical or dermoscopic features are concerning
• Lesions show significant change
• The diagnosis cannot be confidently excluded
Biopsy provides definitive information that cannot be obtained through visual examination alone.
Microscopic analysis defines melanoma characteristics.
Under the microscope, pathologic evaluation assesses
• Presence of malignant melanocytes
• Depth of invasion into the skin
• Growth pattern and cellular features
These findings are central to confirming melanoma and determining its stage.
The skin reacts to both internal and external factors.
Spec. MD. Esengül Kaya
Dermatology
Assoc. Prof. MD. Ece Altun
Dermatology
Spec. MD. Vahid Ahmadi
Dermatology
Spec. MD. İRFAN QEHREMANOV
Dermatology
Prof. MD. Sevilay Oğuz Kılıç
Dermatology
Spec. MD. Marziyeh Javadpour
Dermatology
Spec. MD. Betül Kızılkan
Dermatology
Spec. MD. Meryem Ayşit
Dermatology
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Advanced cases require broader assessment.
When melanoma shows features suggesting advanced disease, evaluation may include assessment of nearby lymph nodes or other areas of the body. This step is guided by clinical findings and staging considerations rather than performed routinely for all cases.
Accurate diagnosis avoids unnecessary intervention.
Many benign moles can appear irregular or dark. Evaluation focuses on identifying patterns consistent with benign growth versus malignant transformation, using clinical experience and diagnostic tools to reduce uncertainty.
Early and accurate diagnosis of melanoma allows timely intervention and significantly influences outcomes. Dermatologic evaluation emphasizes vigilance, structured assessment, and appropriate use of diagnostic tools to identify melanoma at the earliest possible stage.
Spec. MD. Betül Kızılkan
Dermatology
Assoc. Prof. MD. Ece Altun
Dermatology
Spec. MD. İRFAN QEHREMANOV
Dermatology
Prof. MD. İlteriş Oğuz
Dermatology
Asst. Prof. MD. Gül Şekerlisoy Tatar
Dermatology
Asst. Prof. MD. Nazlı Caf
Dermatology
Spec. MD. Hatice Kübra Çakı
Dermatology
MD. Gül Şekerlisoy Tatar
Dermatology
It is diagnosed through skin examination and confirmed by biopsy.
It improves accuracy but does not replace biopsy.
When a lesion shows suspicious features or change.
Not always, but significant or concerning changes should be evaluated.
Depth helps determine stage and guides management decisions.
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