Neurology diagnoses and treats disorders of the nervous system, including the brain, spinal cord, and nerves, as well as thought and memory.
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Treating peripheral nerve disorders requires a balance between removing the pathology and preserving function. The stakes are high; removing a tumor often involves sacrificing the nerve fascicles involved, leading to loss of function. Advanced reconstructive techniques and neuromodulation devices like the peripheral nerve stimulator play a massive role in restoring quality of life.
The primary treatment for a malignant peripheral nerve sheath tumor is surgical resection with wide negative margins. This means removing the tumor and a layer of healthy tissue around it to ensure no cancer cells are left behind. Because these tumors grow inside nerves, this often necessitates the removal of the nerve itself.
When a nerve must be cut to remove a tumor or is severed by trauma, surgeons use nerve grafts to bridge the gap. The sural nerve from the leg is commonly used as a donor. Alternatively, nerve transfers can be performed, where a redundant healthy nerve is rewired to power the paralyzed muscles.
For patients left with intractable neuropathic pain after surgery or trauma, a peripheral nerve stimulator can be a game changer. This device involves placing a small electrode next to the damaged nerve. It delivers weak electrical pulses that “distract” the brain, replacing the feeling of pain with a mild tingling sensation or simply blocking the pain signal.
If the cancer spreads, as is common with metastatic melanotic peripheral nerve sheath sarcoma, systemic therapy is required. Standard chemotherapy regimens for sarcomas (like Doxorubicin and Ifosfamide) are used. Unfortunately, these tumors can be resistant to treatment, prompting the search for clinical trials and targeted molecular therapies.
Post operative rehabilitation is critical. If a nerve transfer was performed, the patient must learn to use the “new” nerve to move the “old” muscle. This involves cortical remapping exercises. For pain, desensitization therapy involves exposing the sensitive area to different textures to retrain the brain’s pain response.
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A nerve transfer is a surgery where a working, less important nerve is cut and connected to a more important damaged nerve to restore function, like “plugging it into a new outlet.”
Nerves grow very slowly, about one inch per month. Recovery of muscle function can take many months or even over a year depending on the distance the nerve must grow.
It is very difficult to cure once it has spread (metastasized), but treatment focuses on prolonging life, controlling symptoms, and slowing the growth of the cancer.
The carotid arteries are two vital blood vessels. They supply blood to the brain and head. Many strokes happen because of blockages or ruptures in
l5 Nerve damage in the lower back, especially at the L4-L5 level, can really affect your daily life. The L4-L5 vertebrae are key for supporting
Lower back pain is a big problem worldwide. It often comes from L4 nerve compression. This occurs when the L4 nerve root is compressed. It
Nerve damage is a big problem worldwide, affecting millions. It makes everyday life hard. Surgery can help fix nerve damage from injuries, tumors, and when
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