
The United States stopped routine smallpox vaccination in 1972. This was a big step in the country’s health history. The move came after smallpox was wiped out in the US, thanks to hard work in controlling it.
It’s been a long journey from when the smallpox vaccine was first used by Edward Jenner in 1796. The vaccine was key in fighting smallpox. Its use ended because of successful efforts to stop the disease. The World Health Organization said the world was free of smallpox in 1980. The World Health Assembly then told countries to stop routine smallpox shots.
Key Takeaways
- The US stopped routine smallpox vaccination in 1972.
- The decision was made after the disease was eradicated domestically.
- The smallpox vaccine was first introduced in 1796.
- Global eradication was declared by the World Health Organization in 1980.
- The World Health Assembly recommended ceasing routine smallpox immunization programs.
The History of Smallpox Vaccination in America

The smallpox vaccine has been key in America’s fight against disease. It shows how the country has faced and overcome health challenges. This journey highlights America’s ability to innovate and adapt.
Early Vaccination Efforts in the United States
The smallpox vaccine came to the U.S. in the early 19th century. At first, many were hesitant, but soon saw its benefits. The vaccine’s early use was vital in fighting smallpox outbreaks that had harmed many communities.
The vaccine uses the vaccinia virus, a safer cousin of smallpox. This virus is the heart of the vaccinia vaccine. It helps build immunity against smallpox by exposing people to a milder form of the virus.
Understanding the Vaccinia Virus Vaccine
The vaccinia vaccine is based on the vaccinia virus. It has grown from simple arm-to-arm transfers to modern cell culture vaccines. The smallpox vaccine’s role in preventing this deadly disease is undeniable.
Over time, the vaccinia vaccination process has become more advanced. Today, the vaccine is a cornerstone in smallpox prevention. It sets a precedent for other vaccination efforts.
When Did They Stop Giving the Smallpox Vaccine?

The US stopped using the smallpox vaccine in phases. This was because of global efforts to wipe out smallpox, which were mostly successful.
End of Routine Vaccination in 1972
In 1972, the US stopped vaccinating kids against smallpox. This was because the risk of getting smallpox was low. Also, the vaccine had its own risks.
Cessation for Healthcare Workers in 1976
By 1976, the US also stopped vaccinating healthcare workers against smallpox. The risk of getting smallpox was seen as low. The vaccine’s side effects were thought to be worse than its benefits.
Discontinuation for International Travelers in 1982
In 1982, the US stopped requiring smallpox vaccines for travelers. This change was due to the global fight against smallpox and how the disease was changing.
To show when these changes happened, here’s a table:
| Year | Event | Description |
| 1972 | End of Routine Vaccination | Routine smallpox vaccination for children was discontinued. |
| 1976 | Cessation for Healthcare Workers | Vaccination of healthcare workers against smallpox was stopped. |
| 1982 | Discontinuation for International Travelers | The requirement for smallpox vaccination for international travelers was discontinued. |
The World Health Organization declared smallpox eradicated in 1980. This was a big win for health worldwide. The US stopped smallpox vaccination in phases because of this achievement.
The Eradication of Smallpox
The fight against smallpox is a major win in medical history. It took a global effort with lots of vaccinations and watchful eyes.
The last smallpox case in the US was in 1949. This was a big step in controlling the disease here.
Last US Case in 1949
1949 was a big year for the US. It was when we stopped seeing smallpox naturally. Vaccines played a big role in this success.
Global Eradication Campaign
The World Health Organization (WHO) started the global fight against smallpox in 1958. It lasted until 1977. They used vaccines, watched for the disease, and worked hard to stop it.
Here are some important moments in the fight against smallpox:
| Year | Milestone |
| 1958 | WHO launches global eradication campaign |
| 1949 | Last naturally occurring case in the United States |
| 1977 | Last naturally occurring case worldwide |
| 1980 | WHO declares smallpox eradicated |
WHO Declaration of Eradication in 1980
In 1980, the World Health Organization said smallpox was gone. They checked and checked to make sure there were no more cases.
This victory shows how working together and using vaccines can make a big difference. It’s a lesson for fighting other diseases too.
Conclusion: Smallpox Vaccination Today
We have wiped out smallpox, a disease that once spread fear and death across the globe. Now, we don’t vaccinate everyone against it anymore. The last smallpox case was in 1977, and in 1980, the World Health Organization said it was gone.
Even though we don’t vaccinate everyone, we keep making the smallpox vaccine. We store it for when we might need it again, like for research or to fight off bioterrorism. It’s also helping us fight mpox, a similar virus.
How long the vaccine protects us is something scientists are studying. They think it gives us long-term protection, but they’re not sure how long. So, we don’t vaccinate for smallpox regularly anymore. But, the vaccine is ready if we need it to protect against bioterrorism.
Looking back, we see how big of a difference smallpox vaccination made. It shows us the strength of working together in public health. It also shows us why we need to keep investing in vaccine research.
FAQ
Is there a vaccine for smallpox?
Yes, the smallpox vaccine, also known as the vaccinia vaccine, is used to immunize against smallpox.
Do we stil vaccinate for smallpox?
Routine smallpox vaccination is no longer necessary due to the global eradication of the disease. But the vaccine is kept for future needs.
When did the United States stop vaccinating for smallpox?
The United States stopped routine smallpox vaccination in 1972. Vaccination for healthcare workers ended in 1976. For international travelers, it stopped in 1982.
What is the smallpox vaccine called?
The smallpox vaccine is also known as the vaccinia vaccine. It uses the vaccinia virus to provide immunity against smallpox.
How long does a smallpox vaccine last?
The duration of immunity from the smallpox vaccine varies. But it is generally considered to provide long-term protection.
Is there a vaccination for smallpox?
Yes, the vaccinia vaccine is used to immunize against smallpox. It has been key in controlling and eradicating the disease.
When is smallpox vaccine given?
Smallpox vaccine is no longer given routinely. But it may be given to certain individuals. This includes laboratory workers handling the virus or military personnel.
What year did they stop giving smallpox vaccinations?
Routine smallpox vaccinations were stopped in 1972 in the United States. This marked the end of a long-standing vaccination program.
References
World Health Organization. Evidence-Based Medical Guidance. Retrieved from https://apps.who.int/iris/handle/10665/39485