
Did you know that up to 1 in 3 people in the United States face a risk of kidney disease? Many drugs for pain, heartburn, high blood pressure, and infections can harm your kidney function without warning.
Discover the 17 common medications that can causekidney disease, from antibiotics to blood pressure drugs. Our guide explains the risks and prevention.
At Liv Hospital, we focus on catching problems early and using proven methods to keep your kidney health safe. Some medicines can cut blood flow to your kidneys, cause inflammation, or even lead to chronic kidney disease. This article will list the top 17 medications bad for kidneys and offer tips to protect your kidney health.
Key Takeaways
- Certain medications can cause kidney damage and lead to chronic kidney disease.
- Common over-the-counter drugs can harm your kidneys if not used properly.
- Early detection and prevention are key to protecting your kidney health.
- Some medicines can reduce blood flow to the kidneys or cause inflammation.
- Knowing the risks of certain medications helps you take steps to protect your kidneys.
Understanding Medication-Induced Kidney Disease

It’s important to know how medicines can harm our kidneys. Many drugs can hurt kidney health, causing kidney disease.
How Medications Affect Kidney Function
Some medicines can harm kidney function. For example, NSAIDs like ibuprofen and naproxen can cut off blood to the kidneys. Antibiotics like gentamicin can poison kidney cells. This can cause short-term or long-term kidney damage.
Medicines can harm kidneys in different ways:
- Reducing blood flow to the kidneys
- Causes direct toxicity to kidney cells
- Causing inflammation within the kidneys
- Interfering with the kidneys’ ability to filter waste
Prevalence and Risk Factors
Drug-induced kidney injury is a big problem, making up to 60 percent of cases in some places. Studies show that 20 percent of kidney damage comes from both prescription and over-the-counter drugs. Key risk factors include:
- Dehydration: Not drinking enough water can make the kidneys more vulnerable to damage.
- Dose and duration of treatment: Taking more of a drug or using it for longer can increase the risk of kidney damage.
- Pre-existing kidney disease: People with kidney problems are more likely to suffer from drug-induced kidney damage.
Knowing these risks and how medicines affect kidneys can help prevent kidney disease caused by drugs.
What Medications Cause Kidney Disease: 17 Common Culprits

Some medicines can really hurt your kidneys. It’s important to know which ones are the biggest risks. We’ll look at 17 common medicines that can lead to kidney disease. This will help you understand the dangers of your prescriptions.
Pain Relievers and Anti-Inflammatory Drugs
Pain relievers and anti-inflammatory drugs are very common. But, using NSAIDs (Nonsteroidal Anti-Inflammatory Drugs) like ibuprofen and naproxen for a long time can harm your kidneys. These drugs cut down blood flow to your kidneys, causing damage over time.
Examples of NSAIDs to be cautious with include:
- Ibuprofen (Advil, Motrin)
- Naproxen (Aleve)
- Celecoxib (Celebrex)
Antibiotics and Antimicrobials
Some antibiotics can damage your kidneys. Aminoglycoside antibiotics, like gentamicin, are very risky. They can cause acute kidney injury, a sudden kidney damage episode.
Other antimicrobials, like vancomycin and antiviral medications like tenofovir, can also harm your kidneys.
Blood Pressure and Heart Medications
Medicines for blood pressure and heart issues can affect your kidneys. ACE inhibitors and ARBs (Angiotensin II Receptor Blockers) are usually good for your kidneys. But, they can be a problem if there’s a blockage in your kidney arteries.
Lithium, used for bipolar disorder, can also affect your kidneys. Long-term use can lead to chronic kidney disease.
Acid Reducers and Digestive Medications
Proton Pump Inhibitors (PPIs), used to lower stomach acid, can lead to kidney disease with long-term use. Examples include omeprazole (Prilosec) and esomeprazole (Nexium).
It’s key to know these risks and talk to your doctor about them. This ensures your medications are safe for you.
Conclusion: Protecting Your Kidneys While Taking Medications
Keeping your kidneys healthy is key when you’re on medication for different health issues. It’s important to watch your kidney function, drink plenty of water, and work closely with your doctor. This helps lower the risks some medicines can pose.
To protect your kidneys, try to use NSAIDs less and drink lots of water. Checking your kidney function regularly can spot problems early. This way, you can get help right away. By being proactive and knowing the risks of certain medicines, you can avoid kidney disease caused by them.
Our team is here to support and guide you in your health care journey. By understanding the risks and taking steps to prevent them, you can keep your kidneys safe. We’re committed to helping you manage your medications and kidney health. This ensures you get the best care possible.
FAQ
What are some common medications that can cause kidney damage?
Some medicines, like NSAIDs (ibuprofen, naproxen), antibiotics (gentamicin), and acid reducers (PPIs), can harm kidneys. This is more likely with long-term use.
How do NSAIDs affect kidney function?
NSAIDs can cut blood flow to the kidneys. This can damage kidneys and may lead to chronic kidney disease.
Are antibiotics bad for the kidneys?
Yes, some antibiotics, like gentamicin, can harm kidney cells. This can cause acute kidney injury, more so with long use or high doses.
Can blood pressure medications cause kidney disease?
Blood pressure meds are often good for kidneys. But, some, like ACE inhibitors, can harm kidneys if not watched closely.
What is the impact of acid reducers on kidney health?
Long-term use of acid reducers, like PPIs, can raise the risk of kidney disease. This includes chronic kidney disease and acute injury.
How can I protect my kidneys while taking medications?
To keep your kidneys safe, drink plenty of water, check your kidney function often, and talk to your doctor about your meds.
What role does dehydration play in medication-induced kidney disease?
Dehydration can increase kidney damage risk with certain meds. It reduces blood flow to kidneys and makes the meds more toxic.
Can the dose and duration of treatment affect the risk of kidney damage?
Yes, the dose and how long you take a medication can greatly affect kidney damage risk. Higher doses and longer use increase the risk.
Are there any alternative treatments or safer medication options available?
Depending on your health, there might be safer options or alternatives. Talk to your doctor to find out what’s best for you.
How can I monitor my kidney function while taking medications?
Regular blood tests and urine checks can track your kidney health. Your doctor might also suggest other tests.
What are the symptoms of medication-induced kidney disease?
Symptoms vary but can include changes in urination, swelling, fatigue, and shortness of breath. If you notice anything unusual, see your doctor right away.
Can famotidine cause kidney damage?
Famotidine is usually safe when used as directed. But, long-term use or high doses might harm kidneys. Always follow your doctor’s advice.
What are the risks associated with lithium and kidney health?
Lithium, used for mental health, can damage kidneys, mainly with long-term use. It’s key to regularly check your kidney function.
References:
Government Health Resource. Evidence-Based Medical Guidance. Retrieved from https://www.kidney-international.org/article/S0085-2538(15)55692-0/fulltext