Diagnosing Achalasia requires a Barium Swallow, Endoscopy, & High-Resolution Manometry (HRM). Learn about tests, preparation, and how results classify your condition.

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Achalasia: Diagnosis and Staging

Diagnosing Achalasia is a step-by-step process that confirms the lack of proper muscle function in the esophagus and rules out other diseases. The diagnostic journey starts with basic screening tests and progresses to advanced procedures like manometry, which is essential for accurately classifying the disease and guiding treatment.

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Common Screening Tests for Achalasia

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While there are no routine screening tests for the general public, the following procedures are often the first steps taken when a patient presents with classic symptoms like dysphagia (difficulty swallowing) and regurgitation.

Barium Swallow (Esophagogram)

The Barium Swallow is typically the first imaging test ordered to evaluate the structure and function of the esophagus.

  • Step-by-step Procedure: The patient drinks a thick liquid containing Barium, which coats the lining of the esophagus and shows up clearly on X-ray. The radiologist observes the movement of the Barium as it passes down the esophagus and into the stomach.
  • Understanding Test Results: In a patient with achalasia, the Barium will pool and accumulate in the dilated esophagus due to the tightly closed Lower Esophageal Sphincter (LES). The lower esophagus often takes on a tapered appearance, classically described as a “bird’s beak” or “rat-tail” sign. This test provides a strong visual indication of the disease.

Upper Endoscopy (Esophagogastroduodenoscopy – EGD)

Upper Endoscopy is a vital procedure used to directly examine the lining of the upper gastrointestinal tract.

  • Step-by-step Procedure: A thin, flexible tube equipped with a light and camera (endoscope) is passed through the mouth, down the esophagus, and into the stomach.
  • Understanding Test Results: For achalasia, the endoscopy often shows a dilated, food-filled esophagus and a tightly closed LES that resists opening. Crucially, the EGD’s primary role is to rule out pseudoachalasia, which is achalasia-like symptoms caused by a tumor or mass near the LES. If a tumor is found, it changes the diagnosis and treatment plan entirely.
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Advanced Diagnostic Procedures

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If the initial screening tests suggest achalasia, the diagnosis must be confirmed and classified using High-Resolution Manometry.

High-Resolution Manometry (HRM)

HRM is the gold standard for diagnosing achalasia, as it directly measures the pressure and coordination of the esophageal muscles.

  • Step-by-step Procedure: A thin, pressure-sensing catheter is passed through the nose and into the esophagus. The patient is asked to swallow small amounts of water, and the catheter measures the pressure and timing of muscle contractions and LES relaxation in 3D.
  • Understanding Test Results: The key findings for achalasia are:
    • Elevated Integrated Relaxation Pressure (IRP): Confirms that the LES is failing to relax properly.
    • Aperistalsis: Confirms the complete or near-complete lack of coordinated contractions in the esophageal body.
  • Staging/Classification: HRM is used to stage the disease according to the Chicago Classification, which identifies the three main types (Type I, II, and III). This classification is essential because it predicts which treatments (e.g., Pneumatic Dilation vs. POEM) will be most successful.

How to Prepare for Manometry and Endoscopy

Proper preparation ensures the safety and accuracy of these diagnostic tests.

  • Fasting: For both Endoscopy and Manometry, you must fast (no food or drink) for at least 6 to 8 hours before the procedure.
  • Medications: Your doctor will instruct you to temporarily stop certain medications, especially those that affect muscle movement (like nitrates or calcium channel blockers) or those that increase the risk of bleeding (like blood thinners), as these can skew the manometry results or increase surgical risk during endoscopy.
  • Esophageal Clearing: Because achalasia patients often have retained food, the surgeon may recommend a liquid diet for 24 hours before the EGD, or even a brief period of saline lavage, to ensure the esophagus is clear for the camera.

Understanding Your Test Results

Once both the EGD rules out a tumor, and the HRM confirms aperistalsis and elevated IRP, the diagnosis of achalasia is certain.

  • Final Diagnosis: The diagnosis is made when imaging (bird’s beak sign) and manometry (elevated IRP + aperistalsis) are consistent.
  • Treatment Planning: The HRM results dictate the plan. For instance, Type II achalasia has the best prognosis with any treatment, while Type III (Spastic) often requires the more extensive muscle cut offered by the POEM procedure.
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When Do You Need Esophageal Function Testing?

You need advanced esophageal function testing (HRM) when initial screening tests, like the Barium Swallow, show clear functional problems, but a definitive, classified diagnosis is needed before planning definitive treatment (surgery or dilation). HRM is essential because it is the only test that can distinguish achalasia from other similar motility disorders like Diffuse Esophageal Spasm.

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FREQUENTLY ASKED QUESTIONS

What tests are used to diagnose Achalasia?

The primary diagnostic tests are the Barium Swallow (which shows the characteristic “bird’s beak” narrowing), Upper Endoscopy (EGD) (to rule out tumors), and High-Resolution Manometry (HRM), which is the gold standard for measuring muscle function and classifying the disease type.

You must fast (no food or drink) for at least 6 to 8 hours before both procedures. For Endoscopy, you may be asked to follow a clear liquid diet the day before to clear any retained food from the esophagus.

HRM is generally not painful, but it can be uncomfortable. The main discomfort comes from the sensation of the thin catheter being passed through the nose and throat. The procedure is performed without sedation and lasts about 15 to 30 minutes.

High-Resolution Manometry (HRM) is highly accurate (considered the gold standard), providing objective data on muscle failure and sphincter pressure. The Barium Swallow is also highly accurate when showing the classic “bird’s beak” sign.

You need advanced testing like HRM whenever achalasia is suspected based on symptoms and a screening test (like Barium Swallow). HRM is necessary to confirm the specific physiological failures and to determine the Chicago Classification type of achalasia, which directly guides the most effective treatment choice.

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