Clinical Immunology focuses on the immune system’s health. Learn about the diagnosis and treatment of allergies, autoimmune diseases, and immunodeficiencies.
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The management of Sjögren syndrome requires a strategic, multifaceted approach. Because the disease has no cure, the therapeutic goals at Liv Hospital are threefold: to alleviate symptoms of dryness (symptomatic relief), to suppress the underlying systemic inflammation (disease-modifying therapy), and to detect and treat organ-specific complications early. Treatment plans are highly personalized; a patient with mild sicca symptoms will have a vastly different regimen than a patient with pulmonary fibrosis or vasculitis.
This antimalarial drug is the most common medicine used for Sjögren syndrome. It helps with fatigue, joint pain, and mild skin rashes. It works by changing how the immune system signals. The drug is generally safe, but patients need yearly eye exams to check for rare side effects on the eyes.
For patients with significant organ involvement (e.g., lung disease, kidney disease, severe arthritis), stronger immune suppression is needed.
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Likely no. Since the glands are permanently damaged, replacement therapy is lifelong. However, treatments like punctal plugs can reduce the frequency of drops needed.
Yes, but it has side effects like sweating. It should be used with caution in patients with asthma or certain heart conditions.
Hydroxychloroquine is mainly for joint pain and fatigue. While it treats the underlying autoimmunity, it does not typically reverse established glandular dryness.
They carry risks, including increased susceptibility to infections, but they are powerful tools necessary for saving organs in severe disease.
Standard contacts are difficult due to dryness. Scleral lenses, which are large, fluid-filled hard lenses, are a fantastic option for Sjögren patients as they bathe the cornea in liquid.
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